(Q37763407)

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Opioids and anxiety.

scientific article published on 08 June 2010

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4 February 2020

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Opioids and anxiety (English)

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4 February 2020

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E A Rabiner

2

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4 February 2020

D J Nutt

4

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8 June 2010

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4 February 2020

Journal of Psychopharmacology

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1415-1433

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Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated

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Kappa receptors mediate the peripheral aversive effects of opiates.

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Non-medical use, abuse and dependence on prescription opioids among U.S. adults: psychiatric, medical and substance use correlates

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Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression

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Non-selective opioid receptor antagonism of the antidepressant-like effect of venlafaxine in the forced swimming test in mice

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Behavioral phenotype of pre-proenkephalin-deficient mice on diverse congenic backgrounds

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Neurochemical mechanisms of the defensive behavior in the dorsal midbrain

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Defense reaction induced by microinjections of bicuculline into the inferior colliculus

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The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations

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Microinjection of naltrexone into the central, but not the basolateral, amygdala blocks the anxiolytic effects of diazepam in the plus maze

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Interactions between opioid-peptides-containing pathways and GABA(A)-receptors-mediated systems modulate panic-like-induced behaviors elicited by electric and chemical stimulation of the inferior colliculus

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Neuroendocrine correlates of lactate-induced anxiety and their response to chronic alprazolam therapy.

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Alpha 2-adrenergic and opiate receptor blockade. Synergistic effects on anxiety in healthy subjects

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High-dose naloxone infusions in normals. Dose-dependent behavioral, hormonal, and physiological responses

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Carbon dioxide-induced emotion and respiratory symptoms in healthy volunteers.

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Role of opioidergic and GABAergic neurotransmission of the nucleus raphe magnus in the modulation of tonic immobility in guinea pigs

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Plasma beta-endorphin response to lactate infusion.

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Association of beta-endorphin with specific clinical symptoms of depression

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Functional and anatomical localization of mu opioid receptors in the striatum, amygdala, and extended amygdala of the nonhuman primate

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Panic disorder: is the PAG involved?

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Evolution of vertebrate opioid receptors

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Role of endogenous opioid system in the regulation of the stress response.

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21 January 2018

Naloxone attenuates the anxiolytic action of diazepam in man.

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21 January 2018

Possible involvement of opioidergic and serotonergic mechanisms in antinociceptive effect of paroxetine in acute pain

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Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited by electrical and chemical stimulation of the deep layers of the superior colliculus and d

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Increased cerebrospinal fluid levels of endorphin immunoreactivity in panic disorder

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The effects of opioid receptor blockade on experimental panic provocation with CO2.

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Opioids inhibit lateral amygdala pyramidal neurons by enhancing a dendritic potassium current.

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Partial anxiolytic action of morphine sulphate following microinjection into the central nucleus of the amygdala in rats

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Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses

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Compulsivity and obsessionality in opioid addiction

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Multicompartmental analysis of [11C]-carfentanil binding to opiate receptors in humans measured by positron emission tomography.

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Manipulation of opiate activity in the amygdala alters memory processes

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Opiate effects in the amygdala central nucleus on heart rate conditioning in rabbits

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A cerebrospinal fluid study of the pathophysiology of panic disorder associated with alcoholism

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Antimanic, antidepressant, and antipanic effects of opiates: clinical, neuroanatomical, and biochemical evidence

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The involvement of the opioidergic system in the antinociceptive mechanism of action of antidepressant compounds

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Effects of naloxone on experimentally induced ischemic pain and on mood in human subjects

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Endorphins: Naloxone Fails to Alter Experimental Pain or Mood in Humans

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Carbon dioxide inhalation induces dose-dependent and age-related negative affectivity

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Role of the opioidergic system and nitric oxide in the analgesic effect of venlafaxine

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Prodynorphin peptide immunocytochemistry in rhesus monkey brain

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Opioids: first lessons from knockout mice

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GABAergic projection from the ventral tegmental area and substantia nigra to the periaqueductal gray region and the dorsal raphe nucleus

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Evidence for endogenous opioid release in the amygdala during positive emotion

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Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin

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mu-Opioid receptors and limbic responses to aversive emotional stimuli

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Effects of naloxone on patients with panic attacks

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Endogenous opioid peptides: multiple agonists and receptors

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Immunohistochemical localization of the cloned mu opioid receptor in the rat CNS.

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Anatomy of CNS opioid receptors

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Naltrexone-induced panic attacks

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Effects of naloxone on diurnal rhythms in mood and endocrine function: a dose-response study in man.

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The use of the plasma concentration-effect relationship as a tool for the study of the mechanism of action of naloxone effects on mood and endocrine function.

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Effect of 12-hour infusion of naloxone on mood and cognition in normal male volunteers

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Naloxone displacement at opioid receptor sites measured in vivo in the human brain

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21 January 2018

Aversive and antiaversive effects of morphine in the dorsal periaqueductal gray of rats submitted to the elevated plus-maze test

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Effects of microinjections of mu and kappa receptor agonists into the dorsal periaqueductal gray of rats submitted to the plus maze test.

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Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning

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Enkephalin is a competitive antagonist of cholecystokinin in the gastrointestinal tract, as predicted from prior conformational analysis

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Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala

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Sensations Evoked by Stimulation in the Midbrain of Man

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Blockade of mu- and activation of kappa-opioid receptors in the dorsal periaqueductal gray matter produce defensive behavior in rats tested in the elevated plus-maze

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Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of mu(1)- and kappa-opioid receptor blockade on escape behavior induced by electrical stimulation of the inferior colliculus

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Heterogeneous distribution and upregulation of mu, delta and kappa opioid receptors in the amygdala

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Do obsessive-compulsive patients and abstinent heroin addicts share a common psychophysiological mechanism?

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Expression of mu, kappa, and delta opioid receptor messenger RNA in the human CNS: a 33P in situ hybridization study

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21 January 2018

Gamma-aminobutyric acidA (GABAA) receptor modulation of morphine inhibition of norepinephrine release

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21 January 2018

Properties of Opiate-Receptor Binding in Rat Brain

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Autoradiographic distribution of multiple classes of opioid receptor binding sites in human forebrain

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Anxiety and congenital central hypoventilation syndrome.

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Naloxone-reversible analgesic response to combat-related stimuli in posttraumatic stress disorder. A pilot study

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21 January 2018

Enkephalinergic afferents of the centromedial amygdala in the rat.

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21 January 2018

Panic, suffocation false alarms, separation anxiety and endogenous opioids

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21 January 2018

The role of delta opioid receptors in the anxiolytic actions of benzodiazepines

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21 January 2018

Female preproenkephalin-knockout mice display altered emotional responses

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21 January 2018

Interface of physical and emotional stress regulation through the endogenous opioid system and mu-opioid receptors

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21 January 2018

Functional and ultrastructural neuroanatomy of interactive intratectal/tectonigral mesencephalic opioid inhibitory links and nigrotectal GABAergic pathways: involvement of GABAA and mu1-opioid receptors in the modulation of panic-like reactions elic

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Characterization and inhibition of a cholecystokinin-inactivating serine peptidase

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Serum antibody for somatostatin-14 and prodynorphin 209-240 in patients with obsessive-compulsive disorder, schizophrenia, Alzheimer's disease, multiple sclerosis, and advanced HIV infection.

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Separation anxiety as a mediator between acute morphine administration and PTSD symptoms in injured children.

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Relationship between acute morphine and the course of PTSD in children with burns

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The antinociceptive effect of venlafaxine in mice is mediated through opioid and adrenergic mechanisms

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Reinforcement processes in opiate addiction: a homeostatic model

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Relapse to drug-seeking: neural and molecular mechanisms

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An enkephalinergic mechanism involved in amygdaloid suppression of affective defence behavior elicited from the midbrain periaqueductal gray in the cat.

1 reference

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21 January 2018

On the antinociceptive effect of fluoxetine, a selective serotonin reuptake inhibitor

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Paradoxical Effects of Opioid Antagonist Naloxone on SSRI-Induced Analgesia and Tolerance in Mice

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Differential effects on naloxone against the diazepam-induced release of behavior in rats in three aversive situations.

1 reference

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21 January 2018

Anesthetics block morphine-induced increases in serotonin release in rat CNS.

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Implication of endogenous opioid system in the learned helplessness model of depression

1 reference

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Involvement of the opioid system in the anxiolytic effect of diazepam in mice

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Mu opioid receptor gene as a candidate for the study of obsessive compulsive disorder with and without tics

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GABA- and peptide-immunoreactivities co-localize in the rat central extended amygdala

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Plasma β-endorphin, pain thresholds and anxiety levels across the human menstrual cycle

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21 January 2018

The role of amygdalar mu-opioid receptors in anxiety-related responses in two rat models

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Prodynorphin-derived peptides are critical modulators of anxiety and regulate neurochemistry and corticosterone

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Cholecystokinin-8S increases dynorphin B, aspartate and glutamate release in the fronto-parietal cortex of the rat via different receptor subtypes

1 reference

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Modulation of neurotransmitter release by cholecystokinin in the neostriatum and substantia nigra of the rat: regional and receptor specificity

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

A potent and selective endogenous agonist for the mu-opiate receptor

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Serotonin-mediated increases in the extracellular levels of beta-endorphin in the arcuate nucleus and nucleus accumbens: a microdialysis study

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Involvement of opioidergic system of the ventral hippocampus, the nucleus accumbens or the central amygdala in anxiety-related behavior

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Intracerebroventricular effects of histaminergic agents on morphine-induced anxiolysis in the elevated plus-maze in rats

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Withdrawal from acute morphine dependence is accompanied by increased anxiety-like behavior in the elevated plus maze

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Synaptic properties and postsynaptic opioid effects in rat central amygdala neurons

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Evidence for the involvement of the opioid system in the agmatine antidepressant-like effect in the forced swimming test

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Worsening of obsessive–compulsive symptoms under methadone tapering

1 reference

https://api.crossref.org/works/10.1177%2F0269881110367726

21 January 2018

Identifiers

10.1177/0269881110367726

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20530588%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20530588%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

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