(Q37763842)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

review article

1 reference

title

Cartilage tumours and bone development: molecular pathology and possible therapeutic targets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Pancras C.W. Hogendoorn

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

author name string

Jay S Wunder

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Benjamin A Alman

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

language of work or name

English

0 references

publication date

10 June 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

481-488

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

Developmental regulation of the growth plate

5 February 2020

cites work

1 reference

Developmental pathways in musculoskeletal neoplasia: involvement of the Indian Hedgehog-parathyroid hormone-related protein pathway

31 March 2020

1 reference

Interaction of Ihh and BMP/Noggin signaling during cartilage differentiation.

31 March 2020

1 reference

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development

31 March 2020

1 reference

HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

31 March 2020

1 reference

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

31 March 2020

1 reference

Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation

31 March 2020

1 reference

Aberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma

31 March 2020

1 reference

A mutant PTH/PTHrP type I receptor in enchondromatosis

31 March 2020

1 reference

PTHR1 mutations associated with Ollier disease result in receptor loss of function

31 March 2020

1 reference

Molecular analysis of the INK4A/INK4A-ARF gene locus in conventional (central) chondrosarcomas and enchondromas: indication of an important gene for tumour progression

31 March 2020

1 reference

31 March 2020

Multiple osteochondromas

1 reference

Multiple osteochondromas: mutation update and description of the multiple osteochondromas mutation database (MOdb).

31 March 2020

1 reference

EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.

31 March 2020

1 reference

The Role of EXT1 in Nonhereditary Osteochondroma: Identification of Homozygous Deletions

31 March 2020

1 reference

A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes.

31 March 2020

1 reference

EXTra hit for mouse osteochondroma.

31 March 2020

1 reference

The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate

31 March 2020

1 reference

Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification

31 March 2020

1 reference

Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas.

31 March 2020

1 reference

Defective chondrocyte proliferation and differentiation in osteochondromas of MHE patients

31 March 2020

1 reference

Regulation of zebrafish skeletogenesis by ext2/dackel and papst1/pinscher

31 March 2020

1 reference

Risk factors for survival and local control in chondrosarcoma of bone

31 March 2020

1 reference

Microvasculature and VEGF expression in cartilaginous tumors

31 March 2020

1 reference

Cartilaginous tumors: fast contrast-enhanced MR imaging

31 March 2020

1 reference

Assessment of interobserver variability and histologic parameters to improve reliability in classification and grading of central cartilaginous tumors

31 March 2020

1 reference

The clinical approach towards chondrosarcoma

31 March 2020

1 reference

The clinical management of chondrosarcoma

31 March 2020

1 reference

Peripheral chondrosarcoma progression is accompanied by decreased Indian Hedgehog signalling.

31 March 2020

1 reference

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

31 March 2020

1 reference

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

31 March 2020

1 reference

Parathyroid hormone-related protein regulates glioma-associated oncogene transcriptional activation: lessons learned from bone development and cartilage neoplasia

31 March 2020

1 reference

Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.

31 March 2020

1 reference

Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study

31 March 2020

1 reference

Loss of heterozygosity and DNA ploidy point to a diverging genetic mechanism in the origin of peripheral and central chondrosarcoma

31 March 2020

1 reference

Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group

31 March 2020

1 reference

Array-comparative genomic hybridization of central chondrosarcoma: identification of ribosomal protein S6 and cyclin-dependent kinase 4 as candidate target genes for genomic aberrations.

31 March 2020

1 reference

Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

31 March 2020

1 reference

Chromosome 9 alterations and trisomy 22 in central chondrosarcoma: a cytogenetic and DNA flow cytometric analysis of chondrosarcoma subtypes

31 March 2020

1 reference

Changes of the p16 gene but not the p53 gene in human chondrosarcoma tissues

31 March 2020

1 reference

Alterations in the regulatory pathway involving p16, pRb and cdk4 in human chondrosarcoma.

31 March 2020

1 reference

Absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas.

31 March 2020

1 reference

Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment.

31 March 2020

1 reference

Tenascin-C promotes cell survival by activation of Akt in human chondrosarcoma cell

31 March 2020

1 reference

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

31 March 2020

1 reference

Activation of the PI3-K/AKT pathway and implications for radioresistance mechanisms in head and neck cancer

31 March 2020

1 reference

PTEN mutation is rare in chondrosarcoma.

31 March 2020

1 reference

Hypoxia induces HIF-1Œ± and VEGF expression in chondrosarcoma cells and chondrocytes

31 March 2020

1 reference

Differential expression of VEGF-A and angiopoietins in cartilage tumors and regulation by interleukin-1beta.

31 March 2020

1 reference

Angiogenic Cytokines in Cartilage Tumors

31 March 2020

2 references

31 March 2020

12 December 2020

Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours

1 reference

Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma

31 March 2020

1 reference

Intrinsic radiation resistance in human chondrosarcoma cells

31 March 2020

1 reference

Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours

31 March 2020

1 reference

cDNA expression profiling of chondrosarcomas: Ollier disease resembles solitary tumours and alteration in genes coding for components of energy metabolism occurs with increasing grade.

31 March 2020

1 reference

Multidrug resistance-1 and p-glycoprotein in human chondrosarcoma cell lines: expression correlates with decreased intracellular doxorubicin and in vitro chemoresistance

31 March 2020

1 reference

Chemotherapy and P-glycoprotein expression in chondrosarcoma

31 March 2020

1 reference

P-glycoprotein expression in cartilaginous tumors

31 March 2020

1 reference

siRNA-based targeting of antiapoptotic genes can reverse chemoresistance in P-glycoprotein expressing chondrosarcoma cells

31 March 2020

1 reference

siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line.

31 March 2020

1 reference

Induction of MDM2-P2 transcripts correlates with stabilized wild-type p53 in betel- and tobacco-related human oral cancer

31 March 2020

1 reference

COX-2 expression in chondrosarcoma: a role for celecoxib treatment?

31 March 2020

1 reference

Usefulness of radiography in differentiating enchondroma from central grade 1 chondrosarcoma

31 March 2020

1 reference

Monoclonal antibody to parathyroid hormone-related protein induces differentiation and apoptosis of chondrosarcoma cells

31 March 2020

1 reference

Estrogen signaling is active in cartilaginous tumors: implications for antiestrogen therapy as treatment option of metastasized or irresectable chondrosarcoma

31 March 2020

1 reference

2-methoxyestradiol induces apoptosis and cell cycle arrest in human chondrosarcoma cells

31 March 2020

1 reference

The effects of histone deacetylase inhibitors on the induction of differentiation in chondrosarcoma cells

31 March 2020

1 reference

Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21.

31 March 2020

1 reference

Alendronate inhibits cell invasion and MMP-2 secretion in human chondrosarcoma cell line

31 March 2020

1 reference

Inhibitory effects of a new bisphosphonate, minodronate, on proliferation and invasion of a variety of malignant bone tumor cells

31 March 2020

1 reference

Consequences of telomerase inhibition by BIBR1532 on proliferation and chemosensitivity of chondrosarcoma cell lines

31 March 2020

1 reference

Trail-induced apoptosis and interaction with cytotoxic agents in soft tissue sarcoma cell lines

31 March 2020

1 reference

CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression

31 March 2020

1 reference

Tyrosine kinase inhibitor SU6668 represses chondrosarcoma growth via antiangiogenesis in vivo

31 March 2020

1 reference

12 December 2020

Reliability of histopathologic and radiologic grading of cartilaginous neoplasms in long bones

1 reference

12 December 2020

Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines.

1 reference

12 December 2020

BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation

1 reference

12 December 2020

Near-haploidy and subsequent polyploidization characterize the progression of peripheral chondrosarcoma.

1 reference

12 December 2020

Chondrosarcoma of bone: an assessment of outcome

1 reference

12 December 2020

The malignant potential of enchondromatosis.

1 reference

12 December 2020

Gains, losses, and amplifications of DNA sequences evaluated by comparative genomic hybridization in chondrosarcomas

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC2869

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20535132%20AND%20SRC:MED&resulttype=core&format=json

release_axt34xg2z5duxpkbroz2exta4u

5 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/axt34xg2z5duxpkbroz2exta4u

24 November 2022

mapped directly with Wikidata item

1 reference