(Q37767586)

22 August 2017

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title

Immune cell crosstalk in type 1 diabetes (English)

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22 August 2017

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Agnès Lehuen

1

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22 August 2017

Julien Diana

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2

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22 August 2017

Paola Zaccone

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3

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22 August 2017

Anne Cooke

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4

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22 August 2017

1 July 2010

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Nature Reviews Immunology

22 August 2017

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22 August 2017

10

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22 August 2017

7

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22 August 2017

501-513

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https://scigraph.springernature.com/pub.10.1038/nri2787

22 August 2017

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cites work

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31 March 2020

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31 March 2020

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Physiological β Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Microorganisms and autoimmunity: making the barren field fertile?

31 March 2020

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Type 1 diabetes development requires both CD4+ and CD8+ T cells and can be reversed by non-depleting antibodies targeting both T cell populations.

31 March 2020

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

31 March 2020

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Immune therapy for type 1 diabetes mellitus-what is unique about anti-CD3 antibodies?

31 March 2020

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The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

31 March 2020

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IPEX and FOXP3: clinical and research perspectives

31 March 2020

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

31 March 2020

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Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

31 March 2020

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B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

31 March 2020

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Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

31 March 2020

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Development of type 1 diabetes despite severe hereditary B-cell deficiency

31 March 2020

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B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

31 March 2020

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Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages

31 March 2020

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The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice

31 March 2020

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Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young no

31 March 2020

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Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes

31 March 2020

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Big mac attack: does it play a direct role for monocytes/macrophages in type 1 diabetes?

31 March 2020

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Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1

31 March 2020

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Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes

31 March 2020

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Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

31 March 2020

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Target cell defense prevents the development of diabetes after viral infection.

31 March 2020

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Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity

31 March 2020

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Natural killer cells are required for accelerated type 1 diabetes driven by interferon-beta.

31 March 2020

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Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice.

31 March 2020

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How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets

31 March 2020

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The activating receptor NKp46 is essential for the development of type 1 diabetes.

31 March 2020

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NKG2D blockade prevents autoimmune diabetes in NOD mice

31 March 2020

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Prolongation of Islet Allograft Survival Following in Vitro Culture (24°C) and a Single Injection of ALS

31 March 2020

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Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody

31 March 2020

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Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue

31 March 2020

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Differential contributions of APC subsets to T cell activation in nonobese diabetic mice

31 March 2020

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Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes

31 March 2020

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Innate immunity and intestinal microbiota in the development of Type 1 diabetes

31 March 2020

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Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function

31 March 2020

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Increased generation of dendritic cells from myeloid progenitors in autoimmune-prone nonobese diabetic mice.

31 March 2020

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Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses

31 March 2020

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Induction of type I diabetes by interferon-alpha in transgenic mice

31 March 2020

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Type 1 interferon as an antiinflammatory agent: inhibition of lipopolysaccharide-induced interleukin-1 beta and induction of interleukin-1 receptor antagonist

31 March 2020

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Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice

31 March 2020

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Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment

31 March 2020

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Decreased blood dendritic cell counts in type 1 diabetic children

31 March 2020

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Type 1 diabetes patients have significantly lower frequency of plasmacytoid dendritic cells in the peripheral blood

31 March 2020

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Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 diabetes and enhance islet autoantigen presentation to T-cells through immune complex capture

31 March 2020

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Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

31 March 2020

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Dendritic cell subsets in health and disease.

31 March 2020

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Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4(+)CD25(+) regulatory T-cells

31 March 2020

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Flt3-ligand treatment prevents diabetes in NOD mice

31 March 2020

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Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development

31 March 2020

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Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

31 March 2020

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The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse.

31 March 2020

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A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice

31 March 2020

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Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.

31 March 2020

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NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner.

31 March 2020

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Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex

31 March 2020

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Impairment of NK cell function by NKG2D modulation in NOD mice

31 March 2020

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Altered natural killer cells in type 1 diabetic patients.

31 March 2020

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Regulation of Autoimmune Diabetes by Complete Freund's Adjuvant Is Mediated by NK Cells

31 March 2020

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NK cells promote islet allograft tolerance via a perforin-dependent mechanism

31 March 2020

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Regulation of type 1 diabetes by NKT cells.

31 March 2020

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alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

31 March 2020

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Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

31 March 2020

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Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

31 March 2020

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The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

31 March 2020

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Synthetic glycolipid OCH prevents insulitis and diabetes in NOD mice

31 March 2020

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Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator

31 March 2020

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NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen

31 March 2020

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NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells

31 March 2020

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Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes

31 March 2020

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Prevention of diabetes in nonobese diabetic mice mediated by CD1d-restricted nonclassical NKT cells

31 March 2020

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Slamf1, the NKT cell control gene Nkt1

31 March 2020

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High frequency of valpha24(+) vbeta11(+) T-cells observed in type 1 diabetes

31 March 2020

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Multiple immuno-regulatory defects in type-1 diabetes

31 March 2020

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

31 March 2020

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Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

31 March 2020

1 reference

Virus-induced diabetes mellitus. XVIII. Inhibition by a nondiabetogenic variant of encephalomyocarditis virus

31 March 2020

1 reference

Direct Involvement of Macrophages in Destruction of β-Cells Leading to Development of Diabetes in Virus-Infected Mice

31 March 2020

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Role of nitric oxide in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice

31 March 2020

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Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

31 March 2020

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Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens

31 March 2020

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Cross-reactive rubella virus and glutamic acid decarboxylase (65 and 67) protein determinants recognised by T cells of patients with type I diabetes mellitus

31 March 2020

1 reference

Human pancreatic islet cell specific 38 kilodalton autoantigen identified by cytomegalovirus-induced monoclonal islet cell autoantibody

31 March 2020

1 reference

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

31 March 2020

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Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

31 March 2020

1 reference

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

31 March 2020

1 reference

A dual role for TNF-alpha in type 1 diabetes: islet-specific expression abrogates the ongoing autoimmune process when induced late but not early during pathogenesis

31 March 2020

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Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.

31 March 2020

1 reference

Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

31 March 2020

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Following a diabetogenic T cell from genesis through pathogenesis

31 March 2020

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Chromogranin A is an autoantigen in type 1 diabetes

31 March 2020

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Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets

31 March 2020

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Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection

31 March 2020

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Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes

31 March 2020

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Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells

31 March 2020

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Rotavirus infection of infant and young adult nonobese diabetic mice involves extraintestinal spread and delays diabetes onset

31 March 2020

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Rotavirus infection accelerates type 1 diabetes in mice with established insulitis

31 March 2020

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Diabetes acceleration or prevention by a coxsackievirus B4 infection: critical requirements for both interleukin-4 and gamma interferon

31 March 2020

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The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

31 March 2020

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NKT cells: friend or foe during viral infections?

31 March 2020

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Immunostimulation circumvents diabetes in NOD/Lt mice

31 March 2020

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Limited effect of CpG ODN in preventing type 1 diabetes in NOD mice

31 March 2020

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Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity

31 March 2020

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IDO mediates TLR9-driven protection from experimental autoimmune diabetes.

31 March 2020

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The effect of innate immunity on autoimmune diabetes and the expression of Toll-like receptors on pancreatic islets.

31 March 2020

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Diabetes-prone NOD mice are resistant to Mycobacterium avium and the infection prevents autoimmune disease

31 March 2020

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Mycobacteria precipitate autoimmune rheumatic disease in NOD mice via an adjuvant-like activity

31 March 2020

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Prevention of overt diabetes and insulitis in NOD mice by a single BCG vaccination

31 March 2020

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Prevention of type I diabetes in NOD mice by adjuvant immunotherapy

31 March 2020

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Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice.

31 March 2020

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Salmonella typhimurium infection in nonobese diabetic mice generates immunomodulatory dendritic cells able to prevent type 1 diabetes.

31 March 2020

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Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human islets

31 March 2020

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Induction of innate immune response through TLR2 and dectin 1 prevents type 1 diabetes.

31 March 2020

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Immune modulation by Schistosoma mansoni antigens in NOD mice: effects on both innate and adaptive immune systems

31 March 2020

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Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice.

31 March 2020

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Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non-obese diabetic mice

31 March 2020

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Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes

31 March 2020

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Isolation of a virus from the pancreas of a child with diabetic ketoacidosis

31 March 2020

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Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization

31 March 2020

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Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations

31 March 2020

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Viruses as therapeutic agents. I. Treatment of nonobese insulin-dependent diabetes mice with virus prevents insulin-dependent diabetes mellitus while maintaining general immune competence

31 March 2020

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Suppression of development of diabetes in NOD mice by lactate dehydrogenase virus infection

31 March 2020

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Persistent MHV (mouse hepatitis virus) infection reduces the incidence of diabetes mellitus in non-obese diabetic mice

31 March 2020

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Murine gammaherpesvirus-68 infection alters self-antigen presentation and type 1 diabetes onset in NOD mice

31 March 2020

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A role for CD45RBlow CD38+ T cells and costimulatory pathways of T-cell activation in protection of non-obese diabetic (NOD) mice from diabetes

31 March 2020

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Streptococcal preparation (OK-432) inhibits development of type I diabetes in NOD mice

31 March 2020

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Transforming growth factor-beta and natural killer T-cells are involved in the protective effect of a bacterial extract on type 1 diabetes

31 March 2020

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Inhibition of autoimmune type 1 diabetes by gastrointestinal helminth infection

31 March 2020

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Inhibition of type 1 diabetes in filaria-infected non-obese diabetic mice is associated with a T helper type 2 shift and induction of FoxP3+ regulatory T cells.

31 March 2020

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A factor of inducing IgE from a filarial parasite prevents insulin-dependent diabetes mellitus in nonobese diabetic mice

31 March 2020

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Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice

31 March 2020

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12 December 2020

Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes

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12 December 2020

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

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12 December 2020

Expression of toll-like receptors in the pancreas of recent-onset fulminant type 1 diabetes

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12 December 2020

Genetics of type 1A diabetes

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12 December 2020

Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse

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12 December 2020

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases

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12 December 2020

Prevention of diabetes in the nonobese diabetic mouse by oral immunological treatments. Comparative efficiency of human insulin and two bacterial antigens, lipopolysacharide from Escherichia coli and glycoprotein extract from Klebsiella pneumoniae

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI2787

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Dimensions Publication ID

22 August 2017

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