(Q37773291)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20636004%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

review article

1 reference

title

Blocking costimulatory pathways: prospects for inducing transplantation tolerance (English)

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7 February 2020

3

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7 February 2020

author name string

Bert Verbinnen

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20636004%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Stefaan W Van Gool

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20636004%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

1 July 2010

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7 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20636004%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

2

1 reference

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7 February 2020

issue

4

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7 February 2020

page(s)

497-509

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Positive and negative selection of T cells

7 February 2020

cites work

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T-cell-receptor affinity and thymocyte positive selection

21 January 2018

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Peripheral tolerance of CD8 T lymphocytes

21 January 2018

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Regulation of the T cell response

21 January 2018

1 reference

21 January 2018

1 reference

Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin

21 January 2018

1 reference

The induction and maintenance of T cell anergy

21 January 2018

1 reference

21 January 2018

The B7 family revisited

1 reference

21 January 2018

The B7-CD28 superfamily

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Regulation of immune and autoimmune responses by ICOS-B7h interaction

21 January 2018

1 reference

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.

21 January 2018

1 reference

CTLA-4 (CD152) and its involvement in autoimmune disease

21 January 2018

1 reference

Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

21 January 2018

1 reference

Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?

21 January 2018

1 reference

Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance

21 January 2018

1 reference

Viral immune evasion due to persistence of activated T cells without effector function

21 January 2018

1 reference

The impact of T cell intrinsic antigen adaptation on peripheral immune tolerance

21 January 2018

1 reference

Regulation of immunity by self-reactive T cells

21 January 2018

1 reference

Regulatory T cells and immune tolerance

21 January 2018

1 reference

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

21 January 2018

1 reference

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

21 January 2018

1 reference

Specialization in tolerance: innate CD(4+)CD(25+) versus acquired TR1 and TH3 regulatory T cells

21 January 2018

1 reference

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

1 reference

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

1 reference

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

1 reference

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

21 January 2018

1 reference

Regulatory T cells and mechanisms of immune system control

21 January 2018

1 reference

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

1 reference

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

21 January 2018

1 reference

Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells

21 January 2018

1 reference

Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand

21 January 2018

1 reference

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

21 January 2018

1 reference

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

21 January 2018

1 reference

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo

21 January 2018

1 reference

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion

21 January 2018

1 reference

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

21 January 2018

1 reference

Treatment with humanized monoclonal antibodies against CD80 and CD86 combined with sirolimus prolongs renal allograft survival in cynomolgus monkeys

21 January 2018

1 reference

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

21 January 2018

1 reference

Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4.

21 January 2018

1 reference

The CD40 pathway in allograft rejection, acceptance, and tolerance

21 January 2018

1 reference

Mechanisms of tolerance induction: blockade of co-stimulation.

21 January 2018

1 reference

Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

21 January 2018

1 reference

Costimulation blockade with belatacept in renal transplantation

21 January 2018

1 reference

Lessons learned from anti-CD40L treatment in systemic lupus erythematosus patients

21 January 2018

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CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation.

21 January 2018

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Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival.

21 January 2018

1 reference

The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity.

21 January 2018

1 reference

Role of the ICOS-B7h costimulatory pathway in the pathophysiology of chronic allograft rejection.

21 January 2018

1 reference

Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade

21 January 2018

1 reference

Beneficial effects of costimulatory blockade with anti-inducible costimulator antibody in conjunction with CTLA4Ig on prevention of islet xenograft rejection from rat to mouse

21 January 2018

1 reference

ICOS-Dependent and -independent functions of memory CD4 T cells in allograft rejection.

21 January 2018

1 reference

OX40 (CD134) blockade inhibits the co-stimulatory cascade and promotes heart allograft survival.

21 January 2018

1 reference

Critical role of OX40 in CD28 and CD154-independent rejection.

21 January 2018

1 reference

The role of the CD134-CD134 ligand costimulatory pathway in alloimmune responses in vivo

21 January 2018

1 reference

Human T cell activation by costimulatory signal-deficient allogeneic cells induces inducible costimulator-expressing anergic T cells with regulatory cell activity.

21 January 2018

1 reference

Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance

21 January 2018

1 reference

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

21 January 2018

1 reference

Contribution of regulatory T cells and effector T cell deletion in tolerance induction by costimulation blockade.

21 January 2018

1 reference

Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation.

21 January 2018

1 reference

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

21 January 2018

1 reference

CTLA-4 control over Foxp3+ regulatory T cell function

21 January 2018

1 reference

CTLA-4 engagement and regulatory CD4+CD25+ T cells independently control CD8+-mediated responses under costimulation blockade.

21 January 2018

1 reference

Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation

21 January 2018

1 reference

IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation

21 January 2018

1 reference

T cell apoptosis by tryptophan catabolism

21 January 2018

1 reference

CTLA-4-Ig regulates tryptophan catabolism in vivo.

21 January 2018

1 reference

Induction of regulatory cells and control of cellular but not vascular rejection by costimulation blockade in hamster-to-rat heart xenotransplantation.

21 January 2018

1 reference

CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase

21 January 2018

1 reference

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

21 January 2018

1 reference

OX40 controls islet allograft tolerance in CD154 deficient mice by regulating FOXP3+ Tregs

21 January 2018

1 reference

OX40 ligand shuts down IL-10-producing regulatory T cells

21 January 2018

1 reference

OX40 costimulation turns off Foxp3+ Tregs.

21 January 2018

1 reference

Mixed chimerism and transplantation tolerance

21 January 2018

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TLR agonists prevent the establishment of allogeneic hematopoietic chimerism in mice treated with costimulation blockade.

21 January 2018

1 reference

Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning

21 January 2018

1 reference

T cell tolerance by clonal elimination in the thymus

21 January 2018

1 reference

Pretransplant Donor Peripheral Blood Mononuclear Cells Infusion Induces Transplantation Tolerance by Generating Regulatory T Cells

21 January 2018

1 reference

Blocking CD40 - CD154 and CD80/CD86 - CD28 interactions during primary allogeneic stimulation results in T cell anergy and high IL-10 production

21 January 2018

1 reference

The role of B7 ligands (CD80 and CD86) in CD152-mediated allograft tolerance: a crosscheck hypothesis

21 January 2018

1 reference

When ligand becomes receptor--tolerance via B7 signaling on DCs

21 January 2018

1 reference

Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment

21 January 2018

1 reference

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/IMT.10.31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20636004%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference