(Q37776040)

23 August 2017

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title

The tuberculosis structural genomics consortium: a structural genomics approach to drug discovery (English)

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23 August 2017

0 references

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2

Thomas R Ioerger

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23 August 2017

Tracey L Musa

1

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23 August 2017

James C Sacchettini

series ordinal

3

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23 August 2017

publication date

28 November 2009

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Advances in protein chemistry and structural biology

23 August 2017

published in

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23 August 2017

volume

77

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23 August 2017

page(s)

41-76

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The PIN-domain toxin-antitoxin array in mycobacteria

23 August 2017

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Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum

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7 January 2021

Structural genomics: beyond the human genome project

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Toxin-antitoxin modules as bacterial metabolic stress managers

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7 January 2021

Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv

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Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening

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7 January 2021

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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7 January 2021

Moxifloxacin versus ethambutol in the initial treatment of tuberculosis: a double-blind, randomised, controlled phase II trial

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7 January 2021

Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A, and their 5'-nor derivatives

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7 January 2021

M. tuberculosis persistence, latency, and drug tolerance

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The TB structural genomics consortium: providing a structural foundation for drug discovery.

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Mycobacterium tuberculosis protein tyrosine phosphatase PtpB structure reveals a diverged fold and a buried active site

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Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

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A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion

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Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis.

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A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis

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7 January 2021

Automatic target selection for structural genomics on eukaryotes

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7 January 2021

Evaluation of 3-deaza-adenosine analogues as ligands for adenosine kinase and inhibitors of Mycobacterium tuberculosis growth

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7 January 2021

Structure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosis

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Predicting absolute ligand binding free energies to a simple model site

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Crystal structures ofMycobacterium tuberculosisS-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors

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7 January 2021

High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme

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7 January 2021

Comprehensive identification of conditionally essential genes in mycobacteria

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7 January 2021

Genetic requirements for mycobacterial survival during infection

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7 January 2021

Worldwide emergence of extensively drug-resistant tuberculosis

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Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs.

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7 January 2021

Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis

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7 January 2021

Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength

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7 January 2021

Lon-dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid-free segregant bacteria.

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7 January 2021

Crystal structures of a pantothenate synthetase fromM. tuberculosisand its complexes with substrates and a reaction intermediate

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7 January 2021

Crystal structure of the pantothenate synthetase from Mycobacterium tuberculosis, snapshots of the enzyme in action

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7 January 2021

A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase

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7 January 2021

Studies on neplanocin A, new antitumor antibiotic. I. Producing organism, isolation and characterization

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7 January 2021

10.1016/S1876-1623(09)77003-8

Identifiers

DOI

1 reference

23 August 2017

1 reference