(Q37777989)

23 August 2017

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title

Sigma receptors and their ligands in cancer biology: overview and new perspectives for cancer therapy (English)

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23 August 2017

author

Christine Decaestecker

3

object named as

Christine Decaestecker

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author name string

Véronique Megalizzi

1

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23 August 2017

Marie Le Mercier

2

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23 August 2017

Christine Decaestecker

3

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23 August 2017

language of work or name

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4 August 2010

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Medicinal Research Reviews

23 August 2017

published in

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23 August 2017

volume

32

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23 August 2017

issue

2

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23 August 2017

page(s)

410-427

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Sigma receptors: recent advances and new clinical potentials

23 August 2017

cites work

1 reference

Clinical trials with sigma ligands

21 January 2018

1 reference

Phencyclidine-induced cognitive deficits in mice are ameliorated by subsequent subchronic administration of donepezil: role of sigma-1 receptors.

21 January 2018

1 reference

The pharmacology of sigma-1 receptors

21 January 2018

1 reference

Sigma receptors and cancer: possible involvement of ion channels

21 January 2018

1 reference

Sigma-1 receptors bind cholesterol and remodel lipid rafts in breast cancer cell lines

21 January 2018

1 reference

Beneficial effects of the sigma1 receptor agonists igmesine and dehydroepiandrosterone against learning impairments in rats prenatally exposed to cocaine

21 January 2018

1 reference

The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator

21 January 2018

1 reference

Sigma receptors: biology and therapeutic potential

21 January 2018

1 reference

Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

21 January 2018

1 reference

Cloning and functional expression of the human type 1 sigma receptor (hSigmaR1)

21 January 2018

1 reference

Purification, molecular cloning, and expression of the mammalian sigma1-binding site

21 January 2018

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The nonsense-mediated decay RNA surveillance pathway

21 January 2018

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Exon-intron structure, analysis of promoter region, and chromosomal localization of the human type 1 sigma receptor gene

21 January 2018

1 reference

High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase

21 January 2018

1 reference

The sigma receptor as a ligand-regulated auxiliary potassium channel subunit

21 January 2018

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Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling.

21 January 2018

1 reference

Subchronic administration of N-[2-(3,4-dichlorophenyl) ethyl]-N-methyl-2-(dimethylamino) ethylamine (BD1047) alters sigma 1 receptor binding.

21 January 2018

1 reference

Sigma and opioid receptors in human brain tumors

21 January 2018

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Expression of sigma 1 receptor in human breast cancer

21 January 2018

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The expression and functional characterization of sigma (sigma) 1 receptors in breast cancer cell lines

21 January 2018

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Screening of anti-glioma effects induced by sigma-1 receptor ligands: potential new use for old anti-psychiatric medicines

21 January 2018

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Sigma-2 receptors as a biomarker of proliferation in solid tumours

21 January 2018

1 reference

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

21 January 2018

1 reference

4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs

21 January 2018

1 reference

Development of a Tc-99m labeled sigma-2 receptor-specific ligand as a potential breast tumor imaging agent

21 January 2018

1 reference

PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma

21 January 2018

1 reference

Anisamide-targeted stealth liposomes: a potent carrier for targeting doxorubicin to human prostate cancer cells

21 January 2018

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Targeted delivery of antisense oligodeoxynucleotide and small interference RNA into lung cancer cells

21 January 2018

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Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA.

21 January 2018

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HIF-1alpha contributes to tumour-selective killing by the sigma receptor antagonist rimcazole

21 January 2018

1 reference

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

21 January 2018

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Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2.

21 January 2018

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Sigma-1 receptor as regulator of neuronal intracellular Ca2+: clinical and therapeutic relevance

21 January 2018

1 reference

Regulating ankyrin dynamics: Roles of sigma-1 receptors

21 January 2018

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Modulation of lipid rafts by Omega-3 fatty acids in inflammation and cancer: implications for use of lipids during nutrition support

21 January 2018

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The nutritional significance of lipid rafts

21 January 2018

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Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

21 January 2018

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Glycosphingolipids and drug resistance.

21 January 2018

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sigma(2) Receptors regulate changes in sphingolipid levels in breast tumor cells

21 January 2018

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The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

21 January 2018

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Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood?

21 January 2018

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Molecular Mechanisms of Tumor Invasion and Metastasis: An Integrated View

21 January 2018

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Cytoskeletal changes in cell transformation and tumorigenesis

21 January 2018

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When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor

21 January 2018

1 reference

RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability

21 January 2018

1 reference

Rho GDP dissociation inhibitor protects cancer cells against drug-induced apoptosis

21 January 2018

1 reference

Activation of Rac1 by Rho-guanine nucleotide dissociation inhibitor-beta with defective isoprenyl-binding pocket

21 January 2018

1 reference

The action of molecular chaperones in the early secretory pathway

21 January 2018

1 reference

A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1.

21 January 2018

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Targeting the endoplasmic reticulum-stress response as an anticancer strategy

21 January 2018

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The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane

21 January 2018

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Engineering eukaryotic protein factories

21 January 2018

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

21 January 2018

1 reference

Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

1 reference

Neuroactive neurosteroids as endogenous effectors for the sigma1 (sigma1) receptor: pharmacological evidence and therapeutic opportunities

21 January 2018

1 reference

A new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes

21 January 2018

1 reference

PET Radiotracers for Imaging the Proliferative Status of Solid Tumors

21 January 2018

1 reference

NE-100, a novel potent sigma ligand, preferentially binds to sigma 1 binding sites in guinea pig brain

21 January 2018

1 reference

[3H]N-[4-(3,4-dihydro-6,7-dimethoxyisoquinolin-2(1H)-yl)butyl]-2-methoxy-5-methylbenzamide: a novel sigma-2 receptor probe

21 January 2018

1 reference

Development of molecular probes for imaging sigma-2 receptors in vitro and in vivo

21 January 2018

1 reference

Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells

21 January 2018

1 reference

Kappa opioid receptor agonists inhibit sigma-1 (sigma 1) receptor binding in guinea-pig brain, liver and spleen: autoradiographical evidence

21 January 2018

1 reference

Radiosynthesis of .sigma. receptor ligands for positron emission tomography: carbon-11 and fluorine-18 labeled guanidines

21 January 2018

1 reference

Interaction with sigma(1) protein, but not N-methyl-D-aspartate receptor, is involved in the pharmacological activity of donepezil

21 January 2018

1 reference

Purification and characterization of the human SR 31747A-binding protein. A nuclear membrane protein related to yeast sterol isomerase

21 January 2018

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The dextromethorphan analog dimemorfan attenuates kainate-induced seizures via sigma1 receptor activation: comparison with the effects of dextromethorphan

21 January 2018

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Subcellular Localization of Sigma-2 Receptors in Breast Cancer Cells Using Two-Photon and Confocal Microscopy

21 January 2018

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Correlation between sigma2 receptor protein expression and histopathologic grade in human bladder cancer

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.20218

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23 August 2017

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