(Q37778884)

23 August 2017

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title

Human endogenous retroviruses and multiple sclerosis: innocent bystanders or disease determinants? (English)

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23 August 2017

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5

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23 August 2017

Joseph M Antony

1

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author name string

Andre M Deslauriers

series ordinal

2

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23 August 2017

Rakesh K Bhat

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3

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23 August 2017

Kristofer K Ellestad

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4

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23 August 2017

language of work or name

English

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publication date

6 August 2010

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Biochimica et Biophysica Acta

23 August 2017

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23 August 2017

1812

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23 August 2017

2

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23 August 2017

162-176

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Reverse transcriptase activity and particle production in B lymphoblastoid cell lines established from lymphocytes of patients with multiple sclerosis

23 August 2017

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12 December 2020

Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways

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12 December 2020

Role of endogenous retroviruses in autoimmune diseases

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12 December 2020

Progress in clinical neurosciences: The neuropathogenesis of HIV infection: host-virus interaction and the impact of therapy.

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12 December 2020

Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis

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12 December 2020

Neutral amino acid transporter ASCT1 is preferentially expressed in L-Ser-synthetic/storing glial cells in the mouse brain with transient expression in developing capillaries

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12 December 2020

Axonal damage in acute multiple sclerosis lesions.

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12 December 2020

Ontogeny and localization of the neutral amino acid transporter ASCT1 in rat brain

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12 December 2020

[Is multiple sclerosis a disease of viral origin?]

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12 December 2020

Endogenous retroviruses and multiple sclerosis

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12 December 2020

Proteomic analysis of protein adsorption: serum amyloid P adsorbs to materials and promotes leukocyte adhesion

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12 December 2020

Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response

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12 December 2020

Reverse transcription in genome evolution

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12 December 2020

Definition and variation of human endogenous retrovirus H.

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12 December 2020

Spliced human endogenous retroviral HERV-H env transcripts in T-cell leukaemia cell lines and normal leukocytes: alternative splicing pattern of HERV-H transcripts

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12 December 2020

Gene–environment interactions in multiple sclerosis: Innate and adaptive immune responses to human endogenous retrovirus and herpesvirus antigens and the lectin complement activation pathway

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12 December 2020

Aboriginals with multiple sclerosis: HLA types and predominance of neuromyelitis optica

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12 December 2020

Retroviruses and schizophrenia revisited

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12 December 2020

Functional regulation of Na+-dependent neutral amino acid transporter ASCT2 by S-nitrosothiols and nitric oxide in Caco-2 cells

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12 December 2020

From endoplasmic-reticulum stress to the inflammatory response

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12 December 2020

MSRV pol sequence copy number as a potential marker of multiple sclerosis.

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12 December 2020

Activation of endoplasmic reticulum stress signaling pathway is associated with neuronal degeneration in MoMuLV-ts1-induced spongiform encephalomyelopathy

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12 December 2020

Viruses, endoplasmic reticulum stress, and interferon responses

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12 December 2020

Analysis of viral and genetic factors in South African patients with multiple sclerosis.

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12 December 2020

HIV infection of the central nervous system: clinical features and neuropathogenesis

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12 December 2020

Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus env sequences

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12 December 2020

The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in astrocytes.

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12 December 2020

Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain

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12 December 2020

Induction of CHOP and apoptosis by nitric oxide in p53-deficient microglial cells

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12 December 2020

Placental endogenous retrovirus (ERV): structural, functional, and evolutionary significance.

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12 December 2020

Structure and function of the human genome

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12 December 2020

Endoplasmic reticulum (ER) stress induced by a neurovirulent mouse retrovirus is associated with prolonged BiP binding and retention of a viral protein in the ER.

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12 December 2020

Mechanism of arsenic trioxide induced apoptosis in cultured human lens epithelium cells

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12 December 2020

Changes in expression and function of syncytin and its receptor, amino acid transport system B(0) (ASCT2), in human placental choriocarcinoma BeWo cells during syncytialization

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12 December 2020

Identification of regulatory elements within the minimal promoter region of the human endogenous ERV9 proviruses: accurate transcription initiation is controlled by an Inr-like element

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12 December 2020

Co-immunization with an HIV-1 Tat transduction peptide-rotavirus enterotoxin fusion protein stimulates a Th1 mucosal immune response in mice

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12 December 2020

Diversity of human endogenous retrovirus class II-like sequences

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12 December 2020

Unreliable real-time PCR analysis of human endogenous retrovirus-W (HERV-W) RNA expression and DNA copy number in multiple sclerosis.

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12 December 2020

Processed pseudogenes of human endogenous retroviruses generated by LINEs: their integration, stability, and distribution

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12 December 2020

TranspoGene and microTranspoGene: transposed elements influence on the transcriptome of seven vertebrates and invertebrates

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12 December 2020

The envelope protein of a human endogenous retrovirus-W family activates innate immunity through CD14/TLR4 and promotes Th1-like responses

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12 December 2020

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

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12 December 2020

Perspectives on the role of endogenous human retroviruses in autoimmune diseases

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12 December 2020

Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line

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12 December 2020

Brains and peripheral blood mononuclear cells of multiple sclerosis (MS) patients hyperexpress MS-associated retrovirus/HERV-W endogenous retrovirus, but not Human herpesvirus 6.

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12 December 2020

Multiple sclerosis-associated retrovirus and MS prognosis: an observational study

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12 December 2020

Redox regulation of chemokine receptor expression

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12 December 2020

Functional epistasis on a common MHC haplotype associated with multiple sclerosis

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12 December 2020

Hygiene hypothesis: innate immunity, malaria and multiple sclerosis

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12 December 2020

Axonal transection in the lesions of multiple sclerosis

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12 December 2020

Multiple sclerosis genetics: leaving no stone unturned

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12 December 2020

Chromosomal distribution and coding capacity of the human endogenous retrovirus HERV-W family

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12 December 2020

Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis

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12 December 2020

Identification of putative endogenous retroviruses actively transcribed in the brain

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12 December 2020

Transcription factor expression and cellular redox in immature oligodendrocyte cell death: effect of Bcl-2.

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12 December 2020

Identification of endogenous retroviral reading frames in the human genome

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12 December 2020

Effectors of demyelination and remyelination in the CNS: implications for multiple sclerosis.

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12 December 2020

Age of onset in concordant twins and other relative pairs with multiple sclerosis.

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12 December 2020

Pathogenesis of multiple sclerosis.

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12 December 2020

Up-regulation of a cellular protein at the translational level by a retrovirus

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12 December 2020

Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress.

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12 December 2020

Herpes simplex virus ICP0 and ICP4 immediate early proteins strongly enhance expression of a retrovirus harboured by a leptomeningeal cell line from a patient with multiple sclerosis

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12 December 2020

Multiple sclerosis--the plaque and its pathogenesis

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12 December 2020

Multiple sclerosis: immunopathogenesis and controversies in defining the cause

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12 December 2020

Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion

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12 December 2020

Characterization of rapid and high-affinity uptake of L-serine in neurons and astrocytes in primary culture

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12 December 2020

The immunoglobulin G heavy chain repertoire in multiple sclerosis plaques is distinct from the heavy chain repertoire in peripheral blood lymphocytes.

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12 December 2020

Ethics of placebo-controlled clinical trials in multiple sclerosis: a reassessment

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12 December 2020

Endogenous retroviruses and MS: using ERVs as disease markers.

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12 December 2020

Nitric-oxide-dependent and independent mechanisms of protection from CNS inflammation during Th1-mediated autoimmunity: evidence from EAE in iNOS KO mice

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12 December 2020

A transgenic mouse model for monitoring endoplasmic reticulum stress

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12 December 2020

Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis.

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12 December 2020

Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia

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12 December 2020

Infrequency of detection of particle-associated MSRV/HERV-W RNA in the synovial fluid of patients with rheumatoid arthritis

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12 December 2020

Comparative Expression of Human Endogenous Retrovirus-W Genes in Multiple Sclerosis

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12 December 2020

Detection of a gliotoxic activity in the cerebrospinal fluid from multiple sclerosis patients

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12 December 2020

HERV-K113 Is Not Associated with Multiple Sclerosis in a Large Family-Based Study

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12 December 2020

Epstein-Barr virus latent membrane protein 2B (LMP2B) co-localizes with LMP2A in perinuclear regions in transiently transfected cells

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12 December 2020

Envelope gene of the human endogenous retrovirus HERV-W encodes a functional retrovirus envelope

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12 December 2020

Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis

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12 December 2020

Mechanisms of inflammation in MS tissue: adhesion molecules and chemokines

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12 December 2020

Multiple sclerosis retrovirus particles and recombinant envelope trigger an abnormal immune response in vitro, by inducing polyclonal Vbeta16 T-lymphocyte activation

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12 December 2020

Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis

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12 December 2020

Novel reliable real-time PCR for differential detection of MSRVenv and syncytin-1 in RNA and DNA from patients with multiple sclerosis

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12 December 2020

Developmental studies of oligodendrocyte precursor cell migration and their implications for transplantation as therapy for multiple sclerosis.

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12 December 2020

The evolution, distribution and diversity of endogenous retroviruses

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12 December 2020

Characterization of the intragenomic spread of the human endogenous retrovirus family HERV-W.

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12 December 2020

Molecular characterization of HERV-H variants associated with multiple sclerosis

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12 December 2020

N-linked glycosylation and sequence changes in a critical negative control region of the ASCT1 and ASCT2 neutral amino acid transporters determine their retroviral receptor functions

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12 December 2020

Transactivation of elements in the human endogenous retrovirus W family by viral infection

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12 December 2020

ER stress and diseases.

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12 December 2020

Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses

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12 December 2020

Physiological knockout of the envelope gene of the single-copy ERV-3 human endogenous retrovirus in a fraction of the Caucasian population

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12 December 2020

The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects

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12 December 2020

Immunology of multiple sclerosis

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12 December 2020

Human endogenous retrovirus expression profiles in samples from brains of patients with schizophrenia and bipolar disorders

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12 December 2020

The evolution, regulation, and function of placenta-specific genes

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12 December 2020

CREB-H: a novel mammalian transcription factor belonging to the CREB/ATF family and functioning via the box-B element with a liver-specific expression

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12 December 2020

Synergistic immune responses induced by endogenous retrovirus and herpesvirus antigens result in increased production of inflammatory cytokines in multiple sclerosis patients

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12 December 2020

Suppression of tumor necrosis factor (TNF-alpha) gene expression by prostaglandin E(2). Role Of early growth response protein-1 (Egr-1)

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12 December 2020

Neuroimmune and neurovirological aspects of human immunodeficiency virus infection

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12 December 2020

Evolution and biological significance of human retroelements

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12 December 2020

A transmissible human endogenous retrovirus

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12 December 2020

Regulation of human endogenous retrovirus W protein expression by herpes simplex virus type 1: implications for multiple sclerosis

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12 December 2020

Human endogenous retroviruses: from infectious elements to human genes

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12 December 2020

IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex

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12 December 2020

Cytokine regulation of env gene expression of human endogenous retrovirus-R in human vascular endothelial cells

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12 December 2020

Roles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD)

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12 December 2020

A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes.

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12 December 2020

Evidence for genomic rearrangements mediated by human endogenous retroviruses during primate evolution

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12 December 2020

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution

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12 December 2020

Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination

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12 December 2020

Expression of an endogenous retrovirus (ERV3 HERV-R) in human reproductive and embryonic tissues--evidence for a function for envelope gene products

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12 December 2020

Identification of a functional envelope protein from the HERV-K family of human endogenous retroviruses

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12 December 2020

The unfolded protein response: a novel component of the hypoxic stress response in tumors.

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12 December 2020

Infectious causes of multiple sclerosis

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12 December 2020

Cell type-specific expression and promoter activity of human endogenous retroviral long terminal repeats

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12 December 2020

Multiple sclerosis--emerging concepts of disease pathogenesis

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12 December 2020

Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting

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12 December 2020

Isolation of three kinds of human endogenous retrovirus-like sequences using tRNA(Pro) as a probe

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12 December 2020

The envelope glycoprotein of human endogenous retrovirus type W uses a divergent family of amino acid transporters/cell surface receptors

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12 December 2020

Astrocytes in multiple sclerosis: a product of their environment

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12 December 2020

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

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12 December 2020

The evolutionary dynamics of endogenous retroviruses

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12 December 2020

In vitro modulation of the multiple sclerosis (MS)-associated retrovirus by cytokines: implications for MS pathogenesis

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12 December 2020

Expression of human endogenous retrovirus k envelope transcripts in human breast cancer

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12 December 2020

Lentiviral neuropathogenesis: comparative neuroinvasion, neurotropism, neurovirulence, and host neurosusceptibility

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12 December 2020

Human endogenous retroviruses: nature, occurrence, and clinical implications in human disease

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12 December 2020

Environmental risk factors in multiple sclerosis

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12 December 2020

Variable transcriptional activity of endogenous retroviruses in human breast cancer

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12 December 2020

Biomarkers and surrogate outcomes in neurodegenerative disease: lessons from multiple sclerosis

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12 December 2020

C-reactive protein receptors on the human monocytic cell line U-937. Evidence for additional binding to Fc gamma RI.

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12 December 2020

Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis.

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12 December 2020

Correlation between disease severity and in vitro cytokine production mediated by MSRV (Multiple Sclerosis associated RetroViral element) envelope protein in patients with multiple sclerosis

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12 December 2020

Interferon-beta1a administration results in a transient increase of serum amyloid A protein and C-reactive protein: comparison with other markers of inflammation

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12 December 2020

Nucleotide sequence of the jaagsiekte retrovirus, an exogenous and endogenous type D and B retrovirus of sheep and goats

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12 December 2020

Retroviral diseases of the nervous system: pathogenic host response or viral gene-mediated neurovirulence?

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12 December 2020

Identification and cloning of endogenous retroviral sequences present in human DNA

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12 December 2020

Multinucleated astrocytes in old demyelinated plaques in a patient with multiple sclerosis

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12 December 2020

Metalloproteinases in biology and pathology of the nervous system.

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12 December 2020

Inhibition of multiple-sclerosis-associated retrovirus as biomarker of interferon therapy

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12 December 2020

Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: involvement of a binding site immediately downstream of the TATA box.

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12 December 2020

A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1.

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12 December 2020

Simultaneous presence of endogenous retrovirus and herpes virus antigens has profound effect on cell-mediated immune responses: implications for multiple sclerosis

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12 December 2020

White matter NMDA receptors: an unexpected new therapeutic target?

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12 December 2020

Quantitative analysis of human endogenous retrovirus-W env in neuroinflammatory diseases.

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12 December 2020

A novel gene from the human endogenous retrovirus K expressed in transformed cells

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12 December 2020

Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene

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12 December 2020

The viruses in all of us: characteristics and biological significance of human endogenous retrovirus sequences

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12 December 2020

MRI as a method to reveal in-vivo pathology in MS.

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12 December 2020

Particle-associated retroviral RNA and tandem RGH/HERV-W copies on human chromosome 7q: possible components of a 'chain-reaction' triggered by infectious agents in multiple sclerosis?

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12 December 2020

Expression of chemokine receptors in the feline reproductive tract and large intestine

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12 December 2020

Isolation of a human endogenous retroviral HERV-H element with an open env reading frame

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12 December 2020

Initial sequencing and analysis of the human genome

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12 December 2020

The pathology of primary progressive multiple sclerosis

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12 December 2020

Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients

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12 December 2020

Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes

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12 December 2020

Molecular mimicry in multiple sclerosis

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12 December 2020

Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis

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12 December 2020

Retrotransposon RNA expression and evidence for retrotransposition events in human oocytes.

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12 December 2020

Multiple sclerosis-associated retroviral agent (MSRV)-stimulated cytokine production in patients with relapsing-remitting multiple sclerosis.

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12 December 2020

Human endogenous retrovirus-K18 Env as a risk factor in multiple sclerosis

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12 December 2020

Multiple sclerosis and multiple sclerosis-associated retrovirus in Sardinia

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12 December 2020

Detection of virion-associated MSRV-RNA in serum of patients with multiple sclerosis

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12 December 2020

Endogenous retrovirus expression in testis and epididymis

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12 December 2020

ATM deficiency induces oxidative stress and endoplasmic reticulum stress in astrocytes

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12 December 2020

Monocyte activation and differentiation augment human endogenous retrovirus expression: implications for inflammatory brain diseases

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12 December 2020

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

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12 December 2020

Repeats in genomic DNA: mining and meaning.

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12 December 2020

Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains

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12 December 2020

Herpesviruses and human endogenous retroviral sequences in the cerebrospinal fluid of multiple sclerosis patients.

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12 December 2020

Neurotransmitters in 3-phosphoglycerate dehydrogenase deficiency

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12 December 2020

Multiple sclerosis-associated retrovirus particles cause T lymphocyte-dependent death with brain hemorrhage in humanized SCID mice model.

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12 December 2020

Novel neuroglial and glioglial relationships mediated by L-serine metabolism

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12 December 2020

Progress in determining the causes and treatment of multiple sclerosis

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12 December 2020

Regulation of the syncytin-1 promoter in human astrocytes by multiple sclerosis-related cytokines

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12 December 2020

Packaging of endogenous retroviral sequences in retroviral vectors produced by murine and human packaging cells

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12 December 2020

Molecular cloning and characterization of MSRV-related sequences associated with retrovirus-like particles

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12 December 2020

Ancient viral protein enrages astrocytes in multiple sclerosis

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12 December 2020

Lack of immune responses against multiple sclerosis-associated retrovirus/human endogenous retrovirus W in patients with multiple sclerosis

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12 December 2020

Human endogenous proviruses

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12 December 2020

A novel human nonviral retroposon derived from an endogenous retrovirus

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12 December 2020

The prospects for neuroprotection in MS

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12 December 2020

Inhibition of sphingolipid synthesis by cycloserine in vitro and in vivo

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12 December 2020

Detecting the expression of human endogenous retrovirus E envelope transcripts in human prostate adenocarcinoma

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12 December 2020

Our retroviral heritage

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12 December 2020

The pathogenic potential of endogenous retroviruses: facts and fantasies

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12 December 2020

Immunopathogenesis of the multiple sclerosis lesion

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12 December 2020

Molecular characterization and placental expression of HERV-W, a new human endogenous retrovirus family.

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12 December 2020

Antibodies against a human endogenous retrovirus and the preponderance of env splice variants in multiple sclerosis patients

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12 December 2020

Evidence that HERV-K is the endogenous retrovirus sequence that codes for the human teratocarcinoma-derived retrovirus HTDV.

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12 December 2020

Activation of endogenous retrovirus reverse transcriptase in multiple sclerosis patient lymphocytes by inactivated HSV-1, HHV-6 and VZV.

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12 December 2020

Prospective study on the relationship between infections and multiple sclerosis exacerbations.

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12 December 2020

An envelope glycoprotein of the human endogenous retrovirus HERV-W is expressed in the human placenta and fuses cells expressing the type D mammalian retrovirus receptor

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12 December 2020

Blood-brain barrier disruption in simian immunodeficiency virus encephalitis

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12 December 2020

Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: differential transcription in normal human tissues

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12 December 2020

Increased Expression of Endoplasmic Reticulum Stress-Related Signaling Pathway Molecules in Multiple Sclerosis Lesions

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12 December 2020

Lentivirus envelope protein exerts differential neuropathogenic effects depending on the site of expression and target cell

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12 December 2020

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes

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12 December 2020

10.1016/J.BBADIS.2010.07.016

Identifiers

DOI

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23 August 2017

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