(Q37780603)

23 August 2017

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title

Potential use of RNA interference in cancer therapy (English)

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23 August 2017

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3

John Nemunaitis

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23 August 2017

Connor Phalon

1

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23 August 2017

Donald D Rao

series ordinal

2

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23 August 2017

publication date

18 August 2010

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Expert Reviews in Molecular Medicine

23 August 2017

published in

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23 August 2017

volume

12

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23 August 2017

page(s)

e26

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Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes

23 August 2017

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Silencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice

21 January 2018

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The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice

21 January 2018

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MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection

21 January 2018

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Inhibitory effect of siRNA targeting survivin in gastric cancer MGC-803 cells

21 January 2018

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RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinoma in vivo.

21 January 2018

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EpCAM is overexpressed in gastric cancer and its downregulation suppresses proliferation of gastric cancer

21 January 2018

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Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells

21 January 2018

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The knockdown of c-myc expression by RNAi inhibits cell proliferation in human colon cancer HT-29 cells in vitro and in vivo.

21 January 2018

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A small interfering RNA targeting osteopontin as gastric cancer therapeutics

21 January 2018

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Vascular endothelial growth factor-C siRNA delivered via calcium carbonate nanoparticle effectively inhibits lymphangiogenesis and growth of colorectal cancer in vivo

21 January 2018

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Gene silencing of beta-catenin by RNAi inhibits cell proliferation in human esophageal cancer cells in vitro and in nude mice

21 January 2018

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Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo

21 January 2018

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Knockdown of p21-activated kinase 6 inhibits prostate cancer growth and enhances chemosensitivity to docetaxel

21 January 2018

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siRNA-based approaches in cancer therapy

21 January 2018

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Targeted polymers for gene delivery

21 January 2018

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Concepts in in vivo siRNA delivery for cancer therapy

21 January 2018

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shRNA and siRNA delivery to the brain

21 January 2018

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Nonviral delivery vehicles for use in short hairpin RNA-based cancer therapies

21 January 2018

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Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

21 January 2018

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

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The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

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Combinatorial microRNA target predictions

21 January 2018

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Repression of protein synthesis by miRNAs: how many mechanisms?

21 January 2018

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

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TarBase: A comprehensive database of experimentally supported animal microRNA targets

21 January 2018

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21 January 2018

RNAi: RISC gets loaded.

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Mechanisms of gene silencing by double-stranded RNA

21 January 2018

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siRNA and miRNA: an insight into RISCs

21 January 2018

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The ins and outs of RNAi in mammalian cells

21 January 2018

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

21 January 2018

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Dicing and slicing: the core machinery of the RNA interference pathway

21 January 2018

1 reference

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The RNA-induced silencing complex is a Mg2+-dependent endonuclease.

21 January 2018

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Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

21 January 2018

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

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A protein sensor for siRNA asymmetry

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1462399410001584

RNA helicase A interacts with RISC in human cells and functions in RISC loading

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1462399410001584

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

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Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Single processing center models for human Dicer and bacterial RNase III

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

21 January 2018

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

21 January 2018

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Therapeutic application of small interfering RNA directed against bcr-abl transcripts to a patient with imatinib-resistant chronic myeloid leukaemia

21 January 2018

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

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RNA interference technologies and therapeutics: from basic research to products

21 January 2018

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Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression.

21 January 2018

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Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

21 January 2018

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Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

21 January 2018

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Rational design of cationic lipids for siRNA delivery

21 January 2018

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Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.

21 January 2018

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Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo

21 January 2018

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The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

21 January 2018

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RNA interference-mediated inhibition of erythropoietin receptor expression suppresses tumor growth and invasiveness in A2780 human ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS1462399410001584

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Error and attack tolerance of complex networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Gene expression profiles and prognostic markers for primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Modulation of miRNA activity in human cancer: a new paradigm for cancer gene therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Gene expression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

siRNA vs. shRNA: similarities and differences

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

Development and application of siRNA expression vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

7 January 2021

Enhanced target gene knockdown by a bifunctional shRNA: a novel approach of RNA interference

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

7 January 2021

https://api.crossref.org/works/10.1017%2FS1462399410001584

1 reference

7 January 2021

Proof concept for clinical justification of network mapping for personalized cancer therapeutics

1 reference

https://api.crossref.org/works/10.1017%2FS1462399410001584

7 January 2021

10.1017/S1462399410001584

Identifiers

DOI

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23 August 2017

1 reference