(Q37784734)

23 August 2017

title

How strontium ranelate, via opposite effects on bone resorption and formation, prevents osteoporosis (English)

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23 August 2017

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3

M L Brandi

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23 August 2017

P J Marie

1

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23 August 2017

D Felsenberg

series ordinal

2

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23 August 2017

language of work or name

English

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publication date

2 September 2010

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Osteoporosis International

23 August 2017

published in

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23 August 2017

volume

22

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23 August 2017

issue

6

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23 August 2017

page(s)

1659-1667

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https://scigraph.springernature.com/pub.10.1007/s00198-010-1369-0

23 August 2017

exact match

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cites work

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A comprehensive review of treatments for postmenopausal osteoporosis

21 January 2018

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Reduced bone formation and increased bone resorption: rational targets for the treatment of osteoporosis

21 January 2018

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In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation

21 January 2018

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Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

S 12911-2 inhibits osteoclastic bone resorption in vitro

21 January 2018

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The calcium-sensing receptor is involved in strontium ranelate-induced osteoclast apoptosis. New insights into the associated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response

21 January 2018

1 reference

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Osteoblasts play key roles in the mechanisms of action of strontium ranelate

21 January 2018

1 reference

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Normal matrix mineralization induced by strontium ranelate in MC3T3-E1 osteogenic cells

21 January 2018

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Strontium ranelate promotes osteoblastic differentiation and mineralization of murine bone marrow stromal cells: involvement of prostaglandins

21 January 2018

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New insights in bone biology: unmasking skeletal effects of the extracellular calcium-sensing receptor.

21 January 2018

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The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Is the calcium receptor a molecular target for the actions of strontium on bone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor

21 January 2018

1 reference

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Strontium promotes calcium oscillations in mouse meiotic oocytes and early embryos through InsP3 receptors, and requires activation of phospholipase and the synergistic action of InsP3.

21 January 2018

1 reference

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The calcium sensing receptor is directly involved in both osteoclast differentiation and apoptosis

21 January 2018

1 reference

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A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium

21 January 2018

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Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice

21 January 2018

1 reference

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Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys (Macaca fascicularis).

21 January 2018

1 reference

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An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants

21 January 2018

1 reference

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S12911-2 reduces bone loss induced by short-term immobilization in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats

21 January 2018

1 reference

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Strontium ranelate treatment improves trabecular and cortical intrinsic bone tissue quality, a determinant of bone strength.

21 January 2018

1 reference

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Strontium ranelate improves implant osseointegration

21 January 2018

1 reference

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Strontium ranelate enhances callus strength more than PTH 1-34 in an osteoporotic rat model of fracture healing

21 January 2018

1 reference

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In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate does not stimulate bone formation in ovariectomized rats.

21 January 2018

1 reference

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The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis

21 January 2018

1 reference

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Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Effects of long-term strontium ranelate treatment on vertebral fracture risk in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Long-term treatment of postmenopausal osteoporosis with strontium ranelate: results at 8 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Comparative effects of teriparatide and strontium ranelate on bone biopsies and biochemical markers of bone turnover in postmenopausal women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Relationship between 3-month changes in biochemical markers of bone remodelling and changes in bone mineral density and fracture incidence in patients treated with strontium ranelate for 3 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Relationship between bone mineral density changes and fracture risk reduction in patients treated with strontium ranelate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Relationship between change in femoral neck bone mineral density and hip fracture incidence during treatment with strontium ranelate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Monitoring strontium ranelate therapy in patients with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Histomorphometric and microCT analysis of bone biopsies from postmenopausal osteoporotic women treated with strontium ranelate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate and alendronate have differing effects on distal tibia bone microstructure in women with osteoporosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00198-010-1369-0

Strontium ranelate treatment enhances hydroxyapatite-coated titanium screws fixation in osteoporotic rats

21 January 2018

1 reference

12 December 2020

Induction of a program gene expression during osteoblast differentiation with strontium ranelate

1 reference

12 December 2020

Strontium ranelate decreases receptor activator of nuclear factor-ΚB ligand-induced osteoclastic differentiation in vitro: involvement of the calcium-sensing receptor

1 reference

12 December 2020

Molecular and functional evidence for multiple Ca2+-binding domains in the type 1 inositol 1,4,5-trisphosphate receptor

1 reference

12 December 2020

Bone material quality in transiliac bone biopsies of postmenopausal osteoporotic women after 3 years of strontium ranelate treatment.

1 reference

12 December 2020

Expression and signal transduction of calcium-sensing receptors in cartilage and bone

1 reference

12 December 2020

Strontium ranelate decreases the incidence of new caudal vertebral fractures in a growing mouse model with spontaneous fractures by improving bone microarchitecture.

1 reference

12 December 2020

Systemic treatment with strontium ranelate promotes tibial fracture healing in ovariectomized rats

1 reference

12 December 2020

The effects of strontium ranelate on biochemical markers of bone turnover and their relationship with bone mineral density

1 reference

12 December 2020

Calcium sensing receptor-dependent and receptor-independent activation of osteoblast replication and survival by strontium ranelate.

1 reference

12 December 2020

Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation

1 reference

12 December 2020

Strontium distribution and interactions with bone mineral in monkey iliac bone after strontium salt (S 12911) administration

1 reference

12 December 2020

Strontium is incorporated into mineral crystals only in newly formed bone during strontium ranelate treatment

1 reference

12 December 2020

Effective doses for strontium ranelate

1 reference

12 December 2020

10.1007/S00198-010-1369-0

Identifiers

DOI

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23 August 2017

1 reference