(Q37789009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20842730%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Genetic instability in inherited and sporadic leukemias (English)

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13 February 2020

2

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13 February 2020

author name string

Henning D Popp

series ordinal

1

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13 February 2020

publication date

1 December 2010

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Genes, Chromosomes and Cancer

13 February 2020

published in

1 reference

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13 February 2020

volume

49

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13 February 2020

issue

12

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13 February 2020

page(s)

1071-1081

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ATR-Chk1 axis protects BCR/ABL leukemia cells from the lethal effect of DNA double-strand breaks.

13 February 2020

cites work

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Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

21 January 2018

1 reference

Kinetic analysis of the Ku-DNA binding activity reveals a redox-dependent alteration in protein structure that stimulates dissociation of the Ku-DNA complex

21 January 2018

1 reference

7 January 2021

Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

1 reference

7 January 2021

Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.

1 reference

7 January 2021

Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D)

1 reference

7 January 2021

Severe combined immunodeficiency and microcephaly in siblings with hypomorphic mutations in DNA ligase IV.

1 reference

7 January 2021

Drug treatment in the development of mismatch repair defective acute leukemia and myelodysplastic syndrome.

1 reference

7 January 2021

Defending genome integrity during DNA replication: a proposed role for RecQ family helicases

1 reference

7 January 2021

Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair

1 reference

7 January 2021

BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair

1 reference

7 January 2021

Microsatellite instability occurs in defined subsets of patients with acute myeloblastic leukaemia

1 reference

7 January 2021

Activation-induced cytidine deaminase acts as a mutator in BCR-ABL1-transformed acute lymphoblastic leukemia cells

1 reference

7 January 2021

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

1 reference

7 January 2021

Increased error-prone non homologous DNA end-joining--a proposed mechanism of chromosomal instability in Bloom's syndrome

1 reference

7 January 2021

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes

1 reference

7 January 2021

Mutations of the TP53 gene in acute myeloid leukemia are strongly associated with a complex aberrant karyotype

1 reference

7 January 2021

Genome maintenance mechanisms for preventing cancer

1 reference

7 January 2021

Polymorphisms in human homeobox HLX1 and DNA repair RAD51 genes increase the risk of therapy-related acute myeloid leukemia

1 reference

7 January 2021

Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated

1 reference

7 January 2021

The role of oxidative stress in carcinogenesis

1 reference

7 January 2021

Oxidative stress and oxidative damage in carcinogenesis

1 reference

7 January 2021

BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance

1 reference

7 January 2021

A 20-year perspective on the International Fanconi Anemia Registry (IFAR).

1 reference

7 January 2021

Instability of BCR-ABL gene in primary and cultured chronic myeloid leukemia stem cells.

1 reference

7 January 2021

SnapShot: DNA mismatch repair

1 reference

7 January 2021

Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.

1 reference

7 January 2021

Analysis of mutations at the DNA repair genes in acute childhood leukaemia

1 reference

7 January 2021

Preferential loss of mismatch repair function in refractory and relapsed acute myeloid leukemia: potential contribution to AML progression

1 reference

7 January 2021

The emerging role of nuclear architecture in DNA repair and genome maintenance

1 reference

7 January 2021

The FLT3 inhibitor PKC412 in combination with cytostatic drugs in vitro in acute myeloid leukemia.

1 reference

7 January 2021

Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells

1 reference

7 January 2021

BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks

1 reference

7 January 2021

A backup DNA repair pathway moves to the forefront

1 reference

7 January 2021

Defending genome integrity during S-phase: putative roles for RecQ helicases and topoisomerase III.

1 reference

7 January 2021

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

1 reference

7 January 2021

Targeted cancer therapies based on the inhibition of DNA strand break repair

1 reference

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

7 January 2021

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

1 reference

7 January 2021

Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia

1 reference

7 January 2021

Fusion tyrosine kinases: a result and cause of genomic instability

1 reference

7 January 2021

DNA double strand breaks (DSB) and non-homologous end joining (NHEJ) pathways in human leukemia

1 reference

7 January 2021

Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

1 reference

7 January 2021

Enhanced phosphorylation of Nbs1, a member of DNA repair/checkpoint complex Mre11-RAD50-Nbs1, can be targeted to increase the efficacy of imatinib mesylate against BCR/ABL-positive leukemia cells

1 reference

7 January 2021

RAD51 homologous recombination repair gene haplotypes and risk of acute myeloid leukaemia

1 reference

7 January 2021

Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML.

1 reference

7 January 2021

Genomic instability in myeloid malignancies: increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair

1 reference

7 January 2021

Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks

1 reference

7 January 2021

Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism

1 reference

7 January 2021

The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells

1 reference

7 January 2021

The genotype distribution of the XRCC1 gene indicates a role for base excision repair in the development of therapy-related acute myeloblastic leukemia

1 reference

7 January 2021

Polymorphisms in genes involved in homologous recombination repair interact to increase the risk of developing acute myeloid leukemia

1 reference

7 January 2021

DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412.

1 reference

7 January 2021

Cancer as a metabolic disease

1 reference

7 January 2021

BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts

1 reference

7 January 2021

Fusion tyrosine kinases induce drug resistance by stimulation of homology-dependent recombination repair, prolongation of G(2)/M phase, and protection from apoptosis

1 reference

7 January 2021

BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells

1 reference

7 January 2021

DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood acute lymphoblastic leukemia

1 reference

7 January 2021

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

1 reference

7 January 2021

Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 reference

7 January 2021

Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect

1 reference

7 January 2021

Endogenous DNA double-strand breaks: Production, fidelity of repair, and induction of cancer

1 reference

7 January 2021

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

1 reference

7 January 2021

FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML.

1 reference

7 January 2021

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

1 reference

7 January 2021

Identifiers

DOI

10.1002/GCC.20823

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20842730%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference