(Q37793347)

23 August 2017

title

Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells (English)

1 reference

23 August 2017

2

Midori Shimada

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20874841

21 July 2024

author name string

Hiroyuki Niida

1

1 reference

23 August 2017

Hiroshi Murakami

3

1 reference

23 August 2017

Makoto Nakanishi

4

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20874841

21 July 2024

publication date

28 September 2010

1 reference

full work available at URL

23 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1349-7006.2010.01719.x

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1349-7006.2010.01719.x

21 July 2024

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

21 July 2024

1 reference

23 August 2017

volume

101

1 reference

23 August 2017

issue

12

1 reference

23 August 2017

page(s)

2505-2509

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Structure, function, and mechanism of ribonucleotide reductases

23 August 2017

cites work

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International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability

21 January 2018

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Identification of new genes regulated by the Crt1 transcription factor, an effector of the DNA damage checkpoint pathway in Saccharomyces cerevisiae

21 January 2018

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Ribonucleotide reductases

21 January 2018

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A comprehensive model for the allosteric regulation of mammalian ribonucleotide reductase. Functional consequences of ATP- and dATP-induced oligomerization of the large subunit

21 July 2024

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Enzymatically active mammalian ribonucleotide reductase exists primarily as an alpha6beta2 octamer

21 July 2024

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

21 July 2024

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Yeast ribonucleotide reductase has a heterodimeric iron-radical-containing subunit

21 July 2024

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Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase

21 July 2024

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Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex

21 July 2024

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Cross-talk between the allosteric effector-binding sites in mouse ribonucleotide reductase

21 July 2024

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Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase

21 July 2024

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DNA damage and cell cycle regulation of ribonucleotide reductase

21 July 2024

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The cell cycle genes cdc22+ and suc22+ of the fission yeast Schizosaccharomyces pombe encode the large and small subunits of ribonucleotide reductase

21 July 2024

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Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae.

21 July 2024

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Checking on the fork: the DNA-replication stress-response pathway

21 July 2024

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Checkpoint responses to replication fork barriers

21 July 2024

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The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor

21 July 2024

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DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1

21 July 2024

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Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality

21 July 2024

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The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1.

21 July 2024

21

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Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathways

21 July 2024

22

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Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms

21 July 2024

23

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase

21 July 2024

24

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Dif1 controls subcellular localization of ribonucleotide reductase by mediating nuclear import of the R2 subunit

21 July 2024

25

1 reference

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The Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunit

21 July 2024

26

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A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools

21 July 2024

27

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Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.

21 July 2024

28

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Nuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein

21 July 2024

29

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Regulation of ribonucleotide reductase by Spd1 involves multiple mechanisms

21 July 2024

30

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Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells

21 July 2024

31

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https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

S-Phase-specific expression of mammalian ribonucleotide reductase R1 and R2 subunit mRNAs

21 July 2024

32

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https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Two YY-1-binding proximal elements regulate the promoter strength of the TATA-less mouse ribonucleotide reductase R1 gene

21 July 2024

33

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

S Phase-specific transcription of the mouse ribonucleotide reductase R2 gene requires both a proximal repressive E2F-binding site and an upstream promoter activating region

21 July 2024

34

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

A ribonucleotide reductase gene is a transcriptional target of p53 and p73

21 July 2024

35

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Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

21 July 2024

36

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

21 July 2024

37

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Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

21 July 2024

38

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Mouse ribonucleotide reductase R2 protein: a new target for anaphase-promoting complex-Cdh1-mediated proteolysis

21 July 2024

39

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase

21 July 2024

40

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Expression of thymidylate synthase in human cells is an early G(1) event regulated by CDK4 and p16INK4A but not E2F.

21 July 2024

41

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Fluctuations in deoxycytidine monophosphate deaminase activity during the cell cycle in synchronous populations of HeLa cells

21 July 2024

42

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species

21 July 2024

43

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase

21 July 2024

44

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage

21 July 2024

45

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

21 July 2024

46

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

21 July 2024

47

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Modulation of enzymes involved in folate dependent one-carbon metabolism by gamma-radiation stress in mice

21 July 2024

48

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Characterization of the 3' --> 5' exonuclease activity found in human nucleoside diphosphate kinase 1 (NDK1) and several of its homologues

21 July 2024

49

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments

21 July 2024

50

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

RRM1-induced metastasis suppression through PTEN-regulated pathways

21 July 2024

51

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Suppression of lung tumor formation by the regulatory subunit of ribonucleotide reductase.

21 July 2024

52

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Ddb1 controls genome stability and meiosis in fission yeast

21 July 2024

53

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response

21 July 2024

54

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Ribonucleotide reductase messenger RNA expression and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients

21 July 2024

55

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Gene expression as a predictive marker of outcome in stage IIB-IIIA-IIIB non-small cell lung cancer after induction gemcitabine-based chemotherapy followed by resectional surgery

21 July 2024

56

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine

21 July 2024

57

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Ribonucleotide reductase M1 gene promoter activity, polymorphisms, population frequencies, and clinical relevance

21 July 2024

58

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

Somatic mutations affect key pathways in lung adenocarcinoma

21 July 2024

59

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2010.01719.X

21 July 2024

Identifiers

1 reference

National Center for Biotechnology Information

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20874841

21 July 2024

1 reference