(Q37793366)

20875047

23 August 2017

title

The multiplicity of action of cannabinoids: implications for treating neurodegeneration (English)

1 reference

23 August 2017

0 references

1 reference

Aoife Gowran

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

Janis Noonan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

Veronica A Campbell

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

publication date

28 September 2010

1 reference

20875047

CNS Neuroscience & Therapeutics

23 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

page(s)

637-644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish1

14 May 2020

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GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity?

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N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

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The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice

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Crucial role for Ser133-phosphorylated form of cyclic AMP-responsive element binding protein signaling in the differentiation and survival of neural progenitors under chronic cerebral hypoperfusion.

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Sodium channel inhibition by anandamide and synthetic cannabimimetics in brain.

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Role of cannabinoids and endocannabinoids in cerebral ischemia

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Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: lights and shadows

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Cannabinoid function in learning, memory and plasticity

21 January 2018

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Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

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Cannabinoid receptor binding and messenger RNA expression in human brain: an in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains

21 January 2018

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Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels.

21 January 2018

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Blockade of 45Ca2+ influx through the N-methyl-D-aspartate receptor ion channel by the non-psychoactive cannabinoid HU-211.

21 January 2018

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CB1 cannabinoid receptors and on-demand defense against excitotoxicity

21 January 2018

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Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells

21 January 2018

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Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores.

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Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity

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Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

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Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms.

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Inflammation and Alzheimer's disease

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A molecular link between the active component of marijuana and Alzheimer's disease pathology

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Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

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Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression

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Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on beta-amyloid-induced toxicity in PC12 cells

21 January 2018

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The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells

21 January 2018

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Delta-9-tetrahydrocannabinol for nighttime agitation in severe dementia

21 January 2018

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Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review

21 January 2018

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Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial

21 January 2018

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Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

21 January 2018

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Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain

21 January 2018

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Supraspinal modulation of pain by cannabinoids: the role of GABA and glutamate

21 January 2018

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Immune tolerance and control of CNS autoimmunity: from animal models to MS patients

21 January 2018

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21 January 2018

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21 January 2018

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The endocannabinoid system is dysregulated in multiple sclerosis and in experimental autoimmune encephalomyelitis

21 January 2018

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Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

21 January 2018

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Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212

21 January 2018

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COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord

21 January 2018

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Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

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Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1.

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Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis

21 January 2018

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The rise and fall of NMDA antagonists for ischemic stroke.

21 January 2018

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An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis

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Anandamide, but not 2-arachidonoylglycerol, accumulates during in vivo neurodegeneration

21 January 2018

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

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Modulation of the endocannabinoid system by focal brain ischemia in the rat is involved in neuroprotection afforded by 17beta-estradiol

21 January 2018

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Release of fatty acid amides in a patient with hemispheric stroke: a microdialysis study

21 January 2018

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Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia

21 January 2018

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Modulation of the balance between cannabinoid CB(1) and CB(2) receptor activation during cerebral ischemic/reperfusion injury

21 January 2018

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Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain

21 January 2018

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Neuroprotective effects of the nonpsychoactive cannabinoid cannabidiol in hypoxic-ischemic newborn piglets.

21 January 2018

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Modulation of cannabinoid receptor activation as a neuroprotective strategy for EAE and stroke

21 January 2018

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Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity.

21 January 2018

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Postural syncope after marijuana: a transcranial Doppler study of the hemodynamics

21 January 2018

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Long term cerebroprotective effects of dexanabinol in a model of focal cerebral ischemia

21 January 2018

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The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia

21 January 2018

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Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance

21 January 2018

1 reference

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The orphan receptor GPR55 is a novel cannabinoid receptor

21 January 2018

1 reference

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Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression

21 January 2018

1 reference

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The endocannabinoid system as a target for the treatment of motor dysfunction

21 January 2018

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High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients.

21 January 2018

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Acute neuronal injury, excitotoxicity, and the endocannabinoid system

21 January 2018

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Effects of rimonabant, a selective cannabinoid CB1 receptor antagonist, in a rat model of Parkinson's disease

21 January 2018

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Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

21 January 2018

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BDNF regulates neuronal sensitivity to endocannabinoids

21 January 2018

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Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions.

21 January 2018

1 reference

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Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.

21 January 2018

1 reference

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APP transgenic modeling of Alzheimer's disease: mechanisms of neurodegeneration and aberrant neurogenesis

21 January 2018

1 reference

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Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis

21 January 2018

1 reference

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Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation

21 January 2018

1 reference

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A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells

21 January 2018

1 reference

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Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

Cannabidiol: a promising drug for neurodegenerative disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

Enhancement of endocannabinoid signaling by fatty acid amide hydrolase inhibition: a neuroprotective therapeutic modality

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease?: The Rotterdam Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2010.00195.X

Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures

21 January 2018

1 reference

12 December 2020

Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current.

1 reference

12 December 2020

Glutamate excitotoxicity in a model of multiple sclerosis

1 reference

12 December 2020

Dexanabinol (HU-211) effect on experimental autoimmune encephalomyelitis: implications for the treatment of acute relapses of multiple sclerosis

1 reference

12 December 2020

The effect of delta-9-tetrahydrocannabinol on forebrain ischemia in rat

1 reference

12 December 2020

Generation of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand, in picrotoxinin-administered rat brain

1 reference

12 December 2020

CB1 cannabinoid receptor induction in experimental stroke

1 reference

12 December 2020

Cannabinoid and kappa opioid receptors reduce potassium K current via activation of G(s) proteins in cultured hippocampal neurons

1 reference

12 December 2020

Increased severity of stroke in CB1 cannabinoid receptor knock-out mice.

1 reference

12 December 2020

Immune-mediated oligodendrocyte injury in multiple sclerosis: molecular mechanisms and therapeutic interventions

1 reference

12 December 2020

Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia.

1 reference

12 December 2020

Palmitoylethanolamide increases after focal cerebral ischemia and potentiates microglial cell motility.

1 reference

12 December 2020

Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains

1 reference

12 December 2020

Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis.

1 reference

12 December 2020

Inflammatory processes in Alzheimer's disease

1 reference

12 December 2020

Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation

1 reference

12 December 2020

Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells

1 reference

12 December 2020

Altered Glutamate Reuptake in Relapsing-Remitting and Secondary Progressive Multiple Sclerosis Cortex: Correlation With Microglia Infiltration, Demyelination, and Neuronal and Synaptic Damage

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12 December 2020

Cannabinoids for the treatment of dementia

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12 December 2020

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

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12 December 2020

Cannabinoid CB1 receptors are early downregulated followed by a further upregulation in the basal ganglia of mice with deletion of specific park genes

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12 December 2020

On the Preparations of the Indian Hemp, or Gunjah (Cannabis Indica), Their Effects on the Animal System in Health, and Their Utility in the Treatment of Tetanus and Other Convulsive Diseases

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12 December 2020

Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist

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12 December 2020

Cannabinoids modulate voltage sensitive potassium A-current in hippocampal neurons via a cAMP-dependent process

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12 December 2020

HU-211, a non-psychotropic cannabinoid, rescues cortical neurones from excitatory amino acid toxicity in culture.

1 reference

12 December 2020

Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells.

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12 December 2020

Cannabinoids inhibit N- and P/Q-type calcium channels in cultured rat hippocampal neurons

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12 December 2020

Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease.

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12 December 2020

10.1111/J.1755-5949.2010.00195.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493861&resulttype=core&format=json

14 May 2020

20875047

1 reference