(Q37796679)

23 August 2017

title

The primary cilium in different tissues-lessons from patients and animal models (English)

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23 August 2017

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2

Brunella Franco

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23 August 2017

Anna D'Angelo

1

1 reference

23 August 2017

publication date

3 October 2010

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23 August 2017

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23 August 2017

volume

26

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23 August 2017

issue

5

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23 August 2017

page(s)

655-662

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Overview of structure and function of mammalian cilia

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The primary cilium at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The perennial organelle: assembly and disassembly of the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Left-right determination: involvement of molecular motor KIF3, cilia, and nodal flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cilia multifunctional organelles at the center of vertebrate left-right asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cilia and the cell cycle?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Functional genomic screen for modulators of ciliogenesis and cilium length

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

A motility in the eukaryotic flagellum unrelated to flagellar beating

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Novel heterotrimeric kinesin-related protein purified from sea urchin eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Piecing together a ciliome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The ciliary proteome database: an integrated community resource for the genetic and functional dissection of cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

A proteomic analysis of human cilia: identification of novel components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The primary cilium as a cellular signaling center: lessons from disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The Ciliopathies: An Emerging Class of Human Genetic Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The dynamic cilium in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Polycystic kidney disease: new understanding in the pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Role of primary cilia in the pathogenesis of polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Mouse models of polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Defective planar cell polarity in polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

A physiological view of the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Kidney-specific inactivation of the Pkd1 gene induces rapid cyst formation in developing kidneys and a slow onset of disease in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cholangiocyte primary cilia in liver health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Polycystic liver diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Liver and kidney disease in ciliopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Hepato-renal pathology in pkd2ws25/- mice, an animal model of autosomal dominant polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Polycystins play a key role in the modulation of cholangiocyte proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The primary cilium as a complex signaling center

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Neuronal primary cilia: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Neurobehavioral development in Joubert syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Bardet-biedl syndrome and brain abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The role of primary cilia in neuronal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The molecular basis of oral-facial-digital syndrome, type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The graded response to Sonic Hedgehog depends on cilia architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

A crucial role for primary cilia in cortical morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Vertebrate Smoothened functions at the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Beta-arrestin-mediated localization of smoothened to the primary cilium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Role of primary cilia in brain development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The neuronal primary cilium: driver of neurogenesis and memory formation in the hippocampal dentate gyrus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

An essential role for dermal primary cilia in hair follicle morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cilia involvement in patterning and maintenance of the skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Osteocyte primary cilium and its role in bone mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Cranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilia of odontoblasts: possible role in molar morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilia regulate Gli/Hedgehog activation in pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Development and disease of the photoreceptor cilium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The retinal ciliopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Deciphering the Endothelial Shear Stress Sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Primary cilia sensitize endothelial cells for fluid shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00467-010-1650-7

Lack of cilia and differentiation defects in the liver of human foetuses with the Meckel syndrome

21 January 2018

1 reference

12 December 2020

Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool

1 reference

12 December 2020

A distinctive triad of malformations of the central nervous system in the Meckel-Gruber syndrome

1 reference

12 December 2020

Cystic diseases of the kidney: molecular biology and genetics

1 reference

12 December 2020

Isolation and characterization of cholangiocyte primary cilia

1 reference

12 December 2020

Primary cilia regulate branching morphogenesis during mammary gland development.

1 reference

12 December 2020

10.1007/S00467-010-1650-7

Identifiers

DOI

1 reference

23 August 2017

1 reference