(Q37799040)

23 August 2017

0 references

The three-gene paraoxonase family: physiologic roles, actions and regulation (English)

1 reference

23 August 2017

The three-gene paraoxonase family: Physiologic roles, actions and regulation (English)

1 reference

https://api.crossref.org/works/10.1016/J.ATHEROSCLEROSIS.2010.08.076

regulation of gene expression

30 July 2024

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20934178

30 July 2024

author name string

Louis-Philippe Précourt

1

1 reference

23 August 2017

Devendra Amre

2

1 reference

23 August 2017

Marie-Claude Denis

3

1 reference

23 August 2017

Jean-Claude Lavoie

4

1 reference

23 August 2017

Edgard Delvin

5

1 reference

23 August 2017

Ernest Seidman

6

1 reference

23 August 2017

Emile Levy

7

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20934178

30 July 2024

publication date

12 October 2010

1 reference

full work available at URL

23 August 2017

https://api.elsevier.com/content/article/PII:S0021915010007240?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.ATHEROSCLEROSIS.2010.08.076

https://api.elsevier.com/content/article/PII:S0021915010007240?httpAccept=text/plain

30 July 2024

1 reference

https://api.crossref.org/works/10.1016/J.ATHEROSCLEROSIS.2010.08.076

30 July 2024

1 reference

23 August 2017

volume

214

1 reference

23 August 2017

issue

1

1 reference

23 August 2017

page(s)

20-36

1 reference

Paraoxonase (PON 1) as a biomarker of susceptibility for organophosphate toxicity

23 August 2017

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Paraoxonase gene Gln192Arg (Q192R) polymorphism is associated with coronary artery spasm

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Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress

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PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients

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The risk of coronary artery disease in population of Taiwan is associated with Cys-Ser 311 polymorphism of human paraoxonase (PON)-2 gene

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The paraoxonase-2-310 polymorphism is associated with the presence of microvascular complications in diabetes mellitus

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Paraoxonase-2 gene (PON2) G148 variant associated with elevated fasting plasma glucose in noninsulin-dependent diabetes mellitus

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30 July 2024

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Comparison of the ability of paraoxonases 1 and 3 to attenuate the in vitro oxidation of low-density lipoprotein and reduce macrophage oxidative stress

30 July 2024

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Identification of paraoxonase 3 gene (PON3) missense mutations in a population of southern Italy

30 July 2024

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Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein

30 July 2024

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Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia.

30 July 2024

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Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

30 July 2024

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Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase

30 July 2024

22

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Calcium-dependent human serum homocysteine thiolactone hydrolase. A protective mechanism against protein N-homocysteinylation

30 July 2024

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Paraoxonase 1 protects against protein N-homocysteinylation in humans

30 July 2024

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Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone

30 July 2024

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Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein

30 July 2024

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Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase

30 July 2024

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Human serum paraoxonases (PON1) Q and R selectively decrease lipid peroxides in human coronary and carotid atherosclerotic lesions: PON1 esterase and peroxidase-like activities

30 July 2024

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Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor.

30 July 2024

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Multiple substrates for paraoxonase-1 during oxidation of phosphatidylcholine by peroxynitrite

30 July 2024

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Phospholipase action of platelet-activating factor acetylhydrolase, but not paraoxonase-1, on long fatty acyl chain phospholipid hydroperoxides

30 July 2024

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Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles

30 July 2024

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Hydrolysis of platelet-activating factor by human serum paraoxonase

30 July 2024

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Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite.

30 July 2024

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Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH

30 July 2024

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30 July 2024

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Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis

30 July 2024

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Paraoxonase 1 (PON1) deficiency in mice is associated with reduced expression of macrophage SR-BI and consequently the loss of HDL cytoprotection against apoptosis

30 July 2024

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Paraoxonase 1 overexpression in mice and its effect on high-density lipoproteins

30 July 2024

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Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

30 July 2024

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30 July 2024

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Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease

30 July 2024

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Comparative evaluation of the protective potentials of human paraoxonase 1 and 3 against CCl4-induced liver injury

30 July 2024

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Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome

30 July 2024

44

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Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice

30 July 2024

45

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Paraoxonase 1 (PON1) enhances HDL-mediated macrophage cholesterol efflux via the ABCA1 transporter in association with increased HDL binding to the cells: a possible role for lysophosphatidylcholine

30 July 2024

46

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Effects of 5' regulatory-region polymorphisms on paraoxonase-gene (PON1) expression

30 July 2024

47

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Genetic polymorphism in paraoxonase 1 (PON1): Population distribution of PON1 activity

30 July 2024

48

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The human serum paraoxonase/arylesterase polymorphism

30 July 2024

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Determinants of variation in human serum paraoxonase activity

30 July 2024

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Determination of paraoxonase 1 status without the use of toxic organophosphate substrates

30 July 2024

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The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

30 July 2024

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The molecular basis of the human serum paraoxonase activity polymorphism.

30 July 2024

54

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Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations

30 July 2024

55

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Two alleles of the human paraoxonase gene produce different amounts of mRNA. An explanation for differences in serum concentrations of paraoxonase associated with the (Leu-Met54) polymorphism

30 July 2024

56

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Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification

30 July 2024

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The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux

30 July 2024

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Polymorphisms in the human paraoxonase (PON1) promoter

30 July 2024

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Paraoxonase-1 promoter haplotypes and serum paraoxonase: a predominant role for polymorphic position - 107, implicating the Sp1 transcription factor

30 July 2024

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A polymorphism upstream from the human paraoxonase (PON1) gene and its association with PON1 expression

30 July 2024

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The paraoxonase PON1 promoter polymorphism C(-107)T is associated with increased serum glucose concentrations in non-diabetic patients

30 July 2024

62

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Paraoxonase promoter polymorphism T(-107)C and relative paraoxonase deficiency as determinants of risk of coronary artery disease.

30 July 2024

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High expressor paraoxonase PON1 gene promoter polymorphisms are associated with reduced risk of vascular disease in younger coronary patients

30 July 2024

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Oxidative stress in smokers and non-smokers

30 July 2024

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Paraoxonase 1 (PON1) activity and lipid parameters in Tunisian smokers

30 July 2024

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Effect of different levels of cigarette smoking on lipid peroxidation, glutathione enzymes and paraoxonase 1 activity in healthy people

30 July 2024

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Differential effects of smoking on myocardial infarction risk according to the Gln/Arg 192 variants of the human paraoxonase gene

30 July 2024

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Dietary modifications and gene polymorphisms alter serum paraoxonase activity in healthy women.

30 July 2024

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Dietary determinants of serum paraoxonase activity in healthy humans

30 July 2024

70

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Light, but not heavy alcohol drinking, stimulates paraoxonase by upregulating liver mRNA in rats and humans

30 July 2024

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Serum paraoxonase in alcohol abusers associated with alcoholic liver disease

30 July 2024

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The French paradox: possible involvement of ethanol in the protective effect against cardiovascular diseases

30 July 2024

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Preservation of paraoxonase activity by wine flavonoids: possible role in protection of LDL from lipid peroxidation

30 July 2024

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Dietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism

30 July 2024

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Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway

30 July 2024

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Pomegranate juice polyphenols increase recombinant paraoxonase-1 binding to high-density lipoprotein: studies in vitro and in diabetic patients

30 July 2024

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Resveratrol has antagonist activity on the aryl hydrocarbon receptor: implications for prevention of dioxin toxicity

30 July 2024

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Induction of the paraoxonase-1 gene expression by resveratrol

30 July 2024

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Oxidative stress and serum paraoxonase activity in experimental hypothyroidism: effect of vitamin E supplementation

30 July 2024

81

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Vitamin E supplementation alters HDL-cholesterol concentration and paraoxonase activity in rabbits fed high-cholesterol diet: comparison with probucol

30 July 2024

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Vitamin C and E intake is associated with increased paraoxonase activity

30 July 2024

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Vitamin C preserves the cardio-protective paraoxonase activity of high-density lipoprotein during oxidant stress

30 July 2024

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Retinoic acid reduces apoptosis and oxidative stress by preservation of SOD protein level

30 July 2024

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Alterations in the lipid metabolism of rat aorta: effects of vitamin a deficiency

30 July 2024

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Pistachio intake increases high density lipoprotein levels and inhibits low-density lipoprotein oxidation in rats

30 July 2024

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Açai palm fruit (Euterpe oleracea Mart.) pulp improves survival of flies on a high fat diet

30 July 2024

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Effects of date ( Phoenix dactylifera L., Medjool or Hallawi Variety) consumption by healthy subjects on serum glucose and lipid levels and on serum oxidative status: a pilot study

30 July 2024

90

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Eucommia ulmoides Oliver leaf extract increases endogenous antioxidant activity in type 2 diabetic mice

30 July 2024

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Short-term feeding of atherogenic diet to mice results in reduction of HDL and paraoxonase that may be mediated by an immune mechanism

30 July 2024

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Gemfibrozil increases paraoxonase activity in type 2 diabetic patients. A new hypothesis of the beneficial action of fibrates?

30 July 2024

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The effect of micronised fenofibrate on paraoxonase activity in patients with coronary heart disease

30 July 2024

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Paraoxonase-1 and serum concentrations of HDL-cholesterol and apoA-I.

30 July 2024

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Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation

30 July 2024

98

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Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio

30 July 2024

99

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Paraoxonase 1 response to a high-fat diet: gender differences in the factors involved

30 July 2024

100

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Dietary fat modulates serum paraoxonase 1 activity in rats

30 July 2024

101

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Reduced postprandial serum paraoxonase activity after a meal rich in used cooking fat

30 July 2024

102

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Replacement of dietary saturated fat with trans fat reduces serum paraoxonase activity in healthy men and women

30 July 2024

103

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Evidence of hypolipemiant and antioxidant properties of argan oil derived from the argan tree (Argania spinosa).

30 July 2024

104

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Consumption of argan oil may have an antiatherogenic effect by improving paraoxonase activities and antioxidant status: Intervention study in healthy men.

30 July 2024

105

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Paraoxonase activity in athletic adolescents.

30 July 2024

106

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Effect of wrestling exercise on oxidative DNA damage, nitric oxide level and paraoxonase activity in adolescent boys

30 July 2024

107

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Human paraoxonase-1 activity in childhood obesity and its relation to leptin and adiponectin levels.

30 July 2024

108

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Alteration of PON1 activity in adult and childhood obesity and its relation to adipokine levels

30 July 2024

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Anti-inflammatory HDL becomes pro-inflammatory during the acute phase response. Loss of protective effect of HDL against LDL oxidation in aortic wall cell cocultures

30 July 2024

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High-density lipoprotein loses its anti-inflammatory properties during acute influenza a infection

30 July 2024

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Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein A-I and paraoxonase-1 by inflammation in murine hepatocytes

30 July 2024

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Proinflammatory Cytokines But Not Acute Phase Serum Amyloid A Or C-Reactive Protein, Downregulate Paraoxonase 1 (Pon1) Expression By Hepg2 Cells

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Paraoxonase activity in the serum and hepatic mRNA levels decrease during the acute phase response

30 July 2024

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Oxidized phospholipids induce changes in hepatic paraoxonase and ApoJ but not monocyte chemoattractant protein-1 via interleukin-6.

30 July 2024

116

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Human paraoxonase-1 gene expression by HepG2 cells is downregulated by interleukin-1β and tumor necrosis factor-α, but is upregulated by interleukin-6

30 July 2024

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Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants

30 July 2024

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PON1 paraoxonase activity is reduced during HDL oxidation and is an indicator of HDL antioxidant capacity

30 July 2024

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30 July 2024

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Oxidative inactivation of paraoxonase--implications in diabetes mellitus and atherosclerosis

30 July 2024

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Iron-ascorbic acid-induced oxidant stress and its quenching by paraoxonase 1 in HDL and the liver: comparison between humans and rats

30 July 2024

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Serum paraoxonase 1 activity and malondialdehyde levels in patients with ulcerative colitis

30 July 2024

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Paraoxonase-1 status in Crohn's disease and ulcerative colitis.

30 July 2024

124

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Paraoxonases are associated with intestinal inflammatory diseases and intracellularly localized to the endoplasmic reticulum

30 July 2024

125

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Paraoxonase 1 (PON1) status in gastroesophageal malignancies and associated paraneoplastic syndromes - connection with inflammation

30 July 2024

126

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Decreased serum paraoxonase-1 activity during intestinal nematode (Nippostrongylus brasiliensis) infection in rats

30 July 2024

127

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Serum paraoxonase undergoes inhibition and proteolysis during experimental acute pancreatitis

30 July 2024

128

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Decreased total antioxidant response and increased oxidative stress in Behcet's disease

30 July 2024

129

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Serum paraoxonase 1 activity status in patients with liver disorders.

30 July 2024

130

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Plasma antioxidative activity during atorvastatin and fluvastatin therapy used in coronary heart disease primary prevention

30 July 2024

131

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Effects of atorvastatin therapy on hypercholesterolemic rabbits with respect to oxidative stress, nitric oxide pathway and homocysteine

30 July 2024

132

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Effect of simvastatin therapy on paraoxonase activity and related lipoproteins in familial hypercholesterolemic patients

30 July 2024

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Atorvastatin effect on high-density lipoprotein-associated paraoxonase activity and oxidative DNA damage

30 July 2024

134

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The effect of atorvastatin therapy on lecithin:cholesterol acyltransferase, cholesteryl ester transfer protein and the antioxidant paraoxonase

30 July 2024

135

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Simvastatin modulates expression of the PON1 gene and increases serum paraoxonase: a role for sterol regulatory element-binding protein-2.

30 July 2024

136

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Pharmacogenetic interaction between paraoxonase-1 gene promoter polymorphism C-107T and statin

30 July 2024

137

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Effect of pitavastatin on transactivation of human serum paraoxonase 1 gene.

30 July 2024

138

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Role of protein kinase C in pitavastatin-induced human paraoxonase I expression in Huh7 cells

30 July 2024

139

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Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins

30 July 2024

140

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Effect of atorvastatin on paraoxonase1 (PON1) and oxidative status

30 July 2024

141

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Antioxidant effect of atorvastatin is independent of PON1 gene T(-107)C, Q192R and L55M polymorphisms in hypercholesterolaemic patients

30 July 2024

142

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Effects of amlodipine, captopril, and bezafibrate on oxidative milieu in rats with fatty liver

30 July 2024

144

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Effects of two different fibric acid derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in type IIb hyperlipoproteinaemia

30 July 2024

145

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Changes in paraoxonase and apolipoprotein A-I, B, C-III and E in subjects with combined familiar hyperlipoproteinemia treated with ciprofibrate

30 July 2024

146

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The effect of fenofibrate on serum paraoxonase activity and inflammatory markers in patients with combined hyperlipidemia

30 July 2024

147

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Ciprofibrate increases paraoxonase activity in patients with metabolic syndrome

30 July 2024

148

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Effects of rosiglitazone and metformin on postprandial paraoxonase-1 and monocyte chemoattractant protein-1 in human immunodeficiency virus-infected patients with lipodystrophy.

30 July 2024

149

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Rosiglitazone modulates fasting and post-prandial paraoxonase 1 activity in type 2 diabetic patients.

30 July 2024

150

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Aspirin use is associated with higher serum concentrations of the anti-oxidant enzyme, paraoxonase-1

30 July 2024

151

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Induction of paraoxonase 1 and apolipoprotein A-I gene expression by aspirin

30 July 2024

152

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Effect of valsartan, an angiotensin II receptor blocker, on markers of oxidation and glycation in Japanese type 2 diabetic subjects: blood pressure-independent effect of valsartan.

30 July 2024

153

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Effect of barnidipine on blood pressure and serum metabolic parameters in patients with essential hypertension: a pilot study.

30 July 2024

154

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Modulation of HDL metabolism by probucol in complete cholesteryl ester transfer protein deficiency

30 July 2024

155

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Probucol up-regulates paraoxonase 1 expression in hepatocytes of hypercholesterolemic rabbits

30 July 2024

156

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Changes in lipid profile and paraoxonase activity in obese patients as a result of orlistat treatment

30 July 2024

157

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Ezetimibe therapy and its influence on oxidative stress and fibrinolytic activity

30 July 2024

158

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Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2.

30 July 2024

159

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Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice

30 July 2024

160

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Adenovirus mediated expression of human paraoxonase 2 protects against the development of atherosclerosis in apolipoprotein E-deficient mice

30 July 2024

161

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Paraoxonase 2 (PON2) decreases high glucose-induced macrophage triglycerides (TG) accumulation, via inhibition of NADPH-oxidase and DGAT1 activity: studies in PON2-deficient mice

30 July 2024

162

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Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1.

30 July 2024

163

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Paraoxonases (PONs) 1, 2, and 3 are expressed in human and mouse gastrointestinal tract and in Caco-2 cell line: selective secretion of PON1 and PON2

30 July 2024

164

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Biological role, protein expression, subcellular localization, and oxidative stress response of paraoxonase 2 in the intestine of humans and rats

30 July 2024

165

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Quorum sensing: the power of cooperation in the world of Pseudomonas.

30 July 2024

166

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Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia.

30 July 2024

167

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Role of quorum sensing by Pseudomonas aeruginosa in microbial keratitis and cystic fibrosis.

30 July 2024

168

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Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin.

30 July 2024

169

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A common mutation in paraoxonase-2 results in impaired lactonase activity.

30 July 2024

170

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Paraoxonase 2 (PON2) expression is upregulated via a reduced-nicotinamide-adenine-dinucleotide-phosphate (NADPH)-oxidase-dependent mechanism during monocytes differentiation into macrophages

30 July 2024

171

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Decreased paraoxonase-2 expression in human carotids during the progression of atherosclerosis

30 July 2024

172

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Urokinase plasminogen activator upregulates paraoxonase 2 expression in macrophages via an NADPH oxidase-dependent mechanism

30 July 2024

173

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Urokinase activates macrophage PON2 gene transcription via the PI3K/ROS/MEK/SREBP-2 signalling cascade mediated by the PDGFR-beta.

30 July 2024

174

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A biphasic U-shape effect of cellular oxidative stress on the macrophage anti-oxidant paraoxonase 2 (PON2) enzymatic activity

30 July 2024

175

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Macrophage paraoxonase 2 (PON2) expression is up-regulated by pomegranate juice phenolic anti-oxidants via PPAR gamma and AP-1 pathway activation

30 July 2024

176

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Comparative expression analysis reveals differences in the regulation of intestinal paraoxonase family members.

30 July 2024

177

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Effect of quercetin on paraoxonase 2 levels in RAW264.7 macrophages and in human monocytes--role of quercetin metabolism.

30 July 2024

178

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Increased macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2) expression in Delta6-desaturase knockout (6-DS KO) mice: beneficial effects of arachidonic acid.

30 July 2024

179

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Transcriptional activation of an anti-oxidant mouse Pon2 gene by dexamethasone

30 July 2024

180

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Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation

30 July 2024

181

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Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids

30 July 2024

182

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Cloning, purification, and refolding of human paraoxonase-3 expressed in Escherichia coli and its characterization

30 July 2024

183

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Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice

30 July 2024

184

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Molecular characterization and expression analysis of the porcine paraoxonase 3 (PON3) gene

30 July 2024

185

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Protective effects of transgene expressed human PON3 against CCl4-induced subacute liver injury in mice

30 July 2024

186

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Temporal and tissue-specific patterns of Pon3 expression in mouse: in situ hybridization analysis

30 July 2024

187

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Paraoxonase-3, a putative circulating antioxidant, is systemically up-regulated in late gestation in the fetal rat, sheep, and human

30 July 2024

188

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The paraoxonases: role in human diseases and methodological difficulties in measurement.

30 July 2024

189

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30 July 2024

Identifiers

1 reference

23 August 2017

1 reference