(Q37800053)

23 August 2017

title

The Hippo pathway in biological control and cancer development (English)

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23 August 2017

Siew Wee Chan

1

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23 August 2017

Chun Jye Lim

2

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23 August 2017

Liming Chen

3

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23 August 2017

Yaan Fun Chong

4

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23 August 2017

Caixia Huang

5

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23 August 2017

Haiwei Song

6

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23 August 2017

Wanjin Hong

7

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23 August 2017

publication date

1 April 2011

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Journal of Cellular Physiology

23 August 2017

published in

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23 August 2017

volume

226

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23 August 2017

issue

4

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23 August 2017

page(s)

928-939

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Integrated profiling of basal and luminal breast cancers.

23 August 2017

cites work

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Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling.

21 January 2018

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Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain

21 January 2018

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Neurofibromatosis type 2.

21 January 2018

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The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie

21 January 2018

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Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

21 January 2018

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The WW domain protein Kibra acts upstream of Hippo in Drosophila.

21 January 2018

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Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

21 January 2018

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Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.

21 January 2018

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The Crumbs complex: from epithelial-cell polarity to retinal degeneration

21 January 2018

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YAP1 increases organ size and expands undifferentiated progenitor cells

21 January 2018

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YAP regulates neural progenitor cell number via the TEA domain transcription factor

21 January 2018

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A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells

21 January 2018

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TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

21 January 2018

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Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice

21 January 2018

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Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands

21 January 2018

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Structural basis of YAP recognition by TEAD4 in the Hippo pathway

21 January 2018

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Delineation of a Fat tumor suppressor pathway

21 January 2018

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miR-372 regulates cell cycle and apoptosis of ags human gastric cancer cell line through direct regulation of LATS2.

21 January 2018

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Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

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Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components

21 January 2018

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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

21 January 2018

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A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration)

21 January 2018

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Kibra is a regulator of the Salvador/Warts/Hippo signaling network

21 January 2018

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SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila

21 January 2018

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Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms.

21 January 2018

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The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

21 January 2018

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DNA copy number alterations and expression of relevant genes in triple-negative breast cancer

21 January 2018

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Pathway discovery in mantle cell lymphoma by integrated analysis of high-resolution gene expression and copy number profiling

21 January 2018

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The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

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TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

21 January 2018

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Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

21 January 2018

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

21 January 2018

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High cancer-specific expression of mesothelin (MSLN) is attributable to an upstream enhancer containing a transcription enhancer factor dependent MCAT motif

21 January 2018

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TAZ as a novel enhancer of MyoD-mediated myogenic differentiation

21 January 2018

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Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma

21 January 2018

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The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation

21 January 2018

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TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

21 January 2018

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Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.

21 January 2018

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Role of the polarity determinant crumbs in suppressing mammalian epithelial tumor progression

21 January 2018

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A Sveinsson's chorioretinal atrophy-associated missense mutation in mouse Tead1 affects its interaction with the co-factors YAP and TAZ

21 January 2018

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TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.

21 January 2018

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Characterization of KIBRA, a novel WW domain-containing protein

21 January 2018

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Control of cell proliferation and apoptosis by mob as tumor suppressor, mats

21 January 2018

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A crucial role of WW45 in developing epithelial tissues in the mouse

21 January 2018

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MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer.

21 January 2018

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

21 January 2018

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TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

21 January 2018

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Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus

21 January 2018

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Structural insights into the YAP and TEAD complex

21 January 2018

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The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

21 January 2018

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The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded

21 January 2018

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Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells

21 January 2018

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

21 January 2018

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Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

21 January 2018

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

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When pathways collide: collaboration and connivance among signalling proteins in development.

21 January 2018

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Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

21 January 2018

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Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics.

21 January 2018

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Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65

21 January 2018

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Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells

21 January 2018

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The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass

21 January 2018

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DNA profiling of primary serous ovarian and fallopian tube carcinomas with array comparative genomic hybridization and multiplex ligation-dependent probe amplification

21 January 2018

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In vivo analysis of Yorkie phosphorylation sites.

21 January 2018

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Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling.

21 January 2018

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Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse

21 January 2018

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Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form

21 January 2018

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Nuclear localization and pro-apoptotic signaling of YAP2 require intact PDZ-binding motif

21 January 2018

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Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

21 January 2018

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

21 January 2018

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The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

21 January 2018

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Molecular mechanisms of glioma invasiveness: the role of proteases

21 January 2018

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X chromosomal abnormalities in basal-like human breast cancer

21 January 2018

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Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded

21 January 2018

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Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival

21 January 2018

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The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.

21 January 2018

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Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma.

21 January 2018

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Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

21 January 2018

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Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

21 January 2018

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Expression of Yes-associated protein in common solid tumors

21 January 2018

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The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage.

21 January 2018

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The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP

21 January 2018

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Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers

21 January 2018

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

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TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

21 January 2018

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Structural and functional analysis of the YAP-binding domain of human TEAD2

21 January 2018

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JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis

21 January 2018

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Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium

21 January 2018

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

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TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

21 January 2018

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The Hippo pathway regulates Wnt/beta-catenin signaling

21 January 2018

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A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

21 January 2018

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The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

21 January 2018

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

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The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway

21 January 2018

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Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development

21 January 2018

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YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation

21 January 2018

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Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

21 January 2018

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The mob as tumor suppressor (mats1) gene is required for growth control in developing zebrafish embryos

21 January 2018

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

21 January 2018

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The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control

21 January 2018

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TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

21 January 2018

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YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway

21 January 2018

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The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals

21 January 2018

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

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TEAD mediates YAP-dependent gene induction and growth control

21 January 2018

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Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein

21 January 2018

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

21 January 2018

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Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.22435

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23 August 2017

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