(Q37802771)

23 August 2017

Strategies for the assessment of protein aggregates in pharmaceutical biotech product development (English)

1 reference

23 August 2017

9

Wim Jiskoot

1 reference

23 August 2017

John den Engelsman

1

1 reference

23 August 2017

Patrick Garidel

2

1 reference

23 August 2017

Ronald Smulders

3

1 reference

23 August 2017

Hans Koll

4

1 reference

23 August 2017

Bryan Smith

5

1 reference

23 August 2017

Stefan Bassarab

6

1 reference

23 August 2017

Andreas Seidl

7

1 reference

23 August 2017

Otmar Hainzl

8

1 reference

23 August 2017

23 October 2010

1 reference

23 August 2017

Pharmaceutical Research

1 reference

23 August 2017

28

1 reference

23 August 2017

4

1 reference

23 August 2017

920-933

1 reference

An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

The critical role of mobile phase composition in size exclusion chromatography of protein pharmaceuticals

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

A critical review of methods for size characterization of non-particulate protein aggregates

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Protein aggregation: pathways, induction factors and analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Online fluorescent dye detection method for the characterization of immunoglobulin G aggregation by size exclusion chromatography and asymmetrical flow field flow fractionation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Protein stability during freezing: separation of stresses and mechanisms of protein stabilization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

A critical review of analytical ultracentrifugation and field flow fractionation methods for measuring protein aggregation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Effects of protein aggregates: an immunologic perspective

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Simultaneous determination of protein aggregation, degradation, and absolute molecular weight by size exclusion chromatography-multiangle laser light scattering

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

The use of asymmetrical flow field-flow fractionation in pharmaceutics and biopharmaceutics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Structure-immunogenicity relationships of therapeutic proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Protein aggregation mediated by cysteine oxidation during the stacking phase of discontinuous buffer SDS-PAGE.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Size-exclusion chromatography with on-line light-scattering, absorbance, and refractive index detectors for studying proteins and their interactions.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Mobile phase containing arginine provides more reliable SEC condition for aggregation analysis.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Detection of protein aggregates by sedimentation velocity analytical ultracentrifugation (SV-AUC): sources of variability and their relative importance

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Protein:protein aggregation induced by protein oxidation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Surfactant-aided size-exclusion chromatography for the purification of immunoglobulin G.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063870

Micelle-associated protein in epoetin formulations: aA risk factor for immunogenicity?

1 September 2018

1 reference

12 December 2020

Silicone oil induced aggregation of proteins

1 reference

12 December 2020

Quantitation of aggregates in therapeutic proteins using sedimentation velocity analytical ultracentrifugation: practical considerations that affect precision and accuracy

1 reference

12 December 2020

IgG particle formation during filling pump operation: a case study of heterogeneous nucleation on stainless steel nanoparticles

1 reference

12 December 2020

Quantitation of protein particles in parenteral solutions using micro-flow imaging

1 reference

12 December 2020

Structural properties of monoclonal antibody aggregates induced by freeze-thawing and thermal stress

1 reference

12 December 2020

Precision of protein aggregation measurements by sedimentation velocity analytical ultracentrifugation in biopharmaceutical applications

1 reference

12 December 2020

10.1007/S11095-010-0297-1

Identifiers

DOI

1 reference

23 August 2017

1 reference

23 August 2017

PubMed publication ID

20972611

1 reference