(Q37803277)

23 August 2017

Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes (English)

1 reference

23 August 2017

Ann-Kristin Mossberg

1

1 reference

23 August 2017

Kenneth Hun Mok

series ordinal

2

1 reference

23 August 2017

Ludmilla A Morozova-Roche

series ordinal

3

1 reference

23 August 2017

Catharina Svanborg

series ordinal

4

1 reference

23 August 2017

language of work or name

English

0 references

publication date

1 November 2010

1 reference

23 August 2017

1 reference

23 August 2017

277

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23 August 2017

22

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23 August 2017

4614-4625

1 reference

Principles that govern the folding of protein chains

23 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Conversion of alpha-lactalbumin to a protein inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Can misfolded proteins be beneficial? The HAMLET case

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

HAMLET treatment delays bladder cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Protein oligomerization induced by oleic acid at the solid-liquid interface--equine lysozyme cytotoxic complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Apoptosis induced by a human milk protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Molecular characterization of alpha-lactalbumin folding variants that induce apoptosis in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Creation and phenotypic analysis of alpha-lactalbumin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Milk protein gene expression in the rat mammary gland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

The evolution of lysozyme and alpha-lactalbumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Molecular divergence of lysozymes and alpha-lactalbumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Equine lysozyme: the molecular basis of folding, self-assembly and innate amyloid toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Structural characterisation and comparison of the native and A-states of equine lysozyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Amyloid protofilaments from the calcium-binding protein equine lysozyme: formation of ring and linear structures depends on pH and metal ion concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Does the cytotoxic effect of transient amyloid oligomers from common equine lysozyme in vitro imply innate amyloid toxicity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Heat-treatment method for producing fatty acid-bound alpha-lactalbumin that induces tumor cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Effect of denaturation of alpha-lactalbumin on the formation of BAMLET (bovine alpha-lactalbumin made lethal to tumor cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Cytotoxic aggregates of alpha-lactalbumin induced by unsaturated fatty acid induce apoptosis in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Multimeric alpha-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Alpha-lactalbumin forms a compact molten globule in the absence of disulfide bonds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Conformational analysis of HAMLET, the folding variant of human alpha-lactalbumin associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Lipids as cofactors in protein folding: stereo-specific lipid-protein interactions are required to form HAMLET (human alpha-lactalbumin made lethal to tumor cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Structural changes of alpha-lactalbumin induced by low pH and oleic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

HAMLET interacts with lipid membranes and perturbs their structure and integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

The interaction of equine lysozyme:oleic acid complexes with lipid membranes suggests a cargo off-loading mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

HAMLET interacts with histones and chromatin in tumor cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Human alpha-lactalbumin made lethal to tumor cells (HAMLET) kills human glioblastoma cells in brain xenografts by an apoptosis-like mechanism and prolongs survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

HAMLET, protein folding, and tumor cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Changes in proteasome structure and function caused by HAMLET in tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

No need to be HAMLET or BAMLET to interact with histones: binding of monomeric alpha-lactalbumin to histones and basic poly-amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

A folding variant of human alpha-lactalbumin induces mitochondrial permeability transition in isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Protease activation in apoptosis induced by MAL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

HAMLET triggers apoptosis but tumor cell death is independent of caspases, Bcl-2 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Autophagy: molecular machinery for self-eating

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Autophagy: dual roles in life and death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Autophagy and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Apoptosis: identification of dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Bladder cancers respond to intravesical instillation of HAMLET (human alpha-lactalbumin made lethal to tumor cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Protein misfolding, functional amyloid, and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Functional amyloid formation within mammalian tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Prions as adaptive conduits of memory and inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Independent Nucleation and Heterogeneous Assembly of Structure During Folding of Equine Lysozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

Compact oleic acid in HAMLET

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

The oleic acid complexes of proteolytic fragments of α-lactalbumin display apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2010.07890.X

10.1111/J.1742-4658.2010.07890.X

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference