(Q37810600)

23 August 2017

Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design (English)

1 reference

23 August 2017

0 references

1 reference

Takeshi Ichinohe

1

1 reference

23 August 2017

1 November 2010

1 reference

Expert Review of Vaccines

23 August 2017

1 reference

23 August 2017

9

1 reference

23 August 2017

11

1 reference

23 August 2017

1315-1324

1 reference

A question of self-preservation: immunopathology in influenza virus infection.

23 August 2017

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The immune system evolved to discriminate infectious nonself from noninfectious self

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The sterile inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

HMGB1 and RAGE in inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Intranasal immunization with formalin-inactivated virus vaccine induces a broad spectrum of heterosubtypic immunity against influenza A virus infection in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Mucosal delivery of inactivated influenza vaccine induces B-cell-dependent heterosubtypic cross-protection against lethal influenza A H5N1 virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Cross-protection against H5N1 influenza virus infection is afforded by intranasal inoculation with seasonal trivalent inactivated influenza vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Synthetic double-stranded RNA poly(I:C) combined with mucosal vaccine protects against influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Cell type-specific involvement of RIG-I in antiviral response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Influenza virus activates inflammasomes via its intracellular M2 ion channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Regulation of adaptive immunity by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Interleukin-1 is responsible for acute lung immunopathology but increases survival of respiratory influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Type I IFN is a powerful mucosal adjuvant for a selective intranasal vaccination against influenza virus in mice and affects antigen capture at mucosal level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Interferon-alpha and interleukin-12 are induced differentially by Toll-like receptor 7 ligands in human blood dendritic cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Autophagy-dependent viral recognition by plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Toll-like receptor control of the adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus-infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Respiratory dendritic cell subsets differ in their capacity to support the induction of virus-specific cytotoxic CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8(+) T cell responses to influenza

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Plasmacytoid dendritic cells capture and cross-present viral antigens from influenza-virus exposed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Acute infection with influenza virus enhances susceptibility to fatal pneumonia following Streptococcus pneumoniae infection in mice with chronic pulmonary colonization with Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Systemic administration of a TLR7 ligand leads to transient immune incompetence due to peripheral-blood leukocyte depletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Increased susceptibility for superinfection with Streptococcus pneumoniae during influenza virus infection is not caused by TLR7-mediated lymphopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Influenza virus-induced glucocorticoids compromise innate host defense against a secondary bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Sustained desensitization to bacterial Toll-like receptor ligands after resolution of respiratory influenza infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Plasmacytoid dendritic cells are dispensable during primary influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

5'-Triphosphate RNA is the ligand for RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

NLRX1 is a regulator of mitochondrial antiviral immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The inflammasomes: guardians of the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Pyroptosis: host cell death and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Inflammasome recognition of influenza virus is essential for adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Intranasal immunization with H5N1 vaccine plus Poly I:Poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Intranasal administration of adjuvant-combined vaccine protects monkeys from challenge with the highly pathogenic influenza A H5N1 virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.118

21 January 2018

Identifiers

DOI

10.1586/ERV.10.118

1 reference

release_mfwzf7sijzdrxomejt7l733ie4

23 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mfwzf7sijzdrxomejt7l733ie4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

21087109

1 reference

PubMed ID

21087109