(Q37818197)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

review article

1 reference

title

Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

ChEBI release 2020-05-28

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Klemens Budde

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Mareen Matz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Marcel Naik

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Petra Glander

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Hans-H Neumayer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

8 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Metabolism & Toxicology

17 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

103-113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142580%20AND%20SRC:MED&resulttype=core&format=json

BK-virus nephropathy in renal transplants-tubular necrosis, MHC-class II expression and rejection in a puzzling game

17 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Sirolimus--challenging current perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Gastrointestinal complications in renal transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Cardiovascular toxicities of immunosuppressive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Effects of steroid avoidance and novel protocols on growth in paediatric renal transplant patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Steroid-free immunosuppression since 1999: 129 pediatric renal transplants with sustained graft and patient benefits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Effect of immunosuppressive agents on long-term survival of renal transplant recipients: focus on the cardiovascular risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Steroid elimination-who, when, how?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Effect of cyclosporine on the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Cyclosporin and organ specific toxicity: clinical aspects, pharmacogenetics and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Mycophenolate blood level monitoring: recent progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Safety considerations with mycophenolate sodium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

The influence of mycophenolate mofetil versus azathioprine and mycophenolic acid pharmacokinetics on the incidence of acute rejection and infectious complications after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Mycophenolate mofetil in renal allograft recipients: a pooled efficacy analysis of three randomized, double-blind, clinical studies in prevention of rejection. The International Mycophenolate Mofetil Renal Transplant Study Groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Influence of immunosuppressive regimens on graft survival and secondary outcomes after kidney transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Mycophenolate mofetil versus azathioprine for prevention of chronic allograft dysfunction in renal transplantation: the MYSS follow-up randomized, controlled clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

mTOR--beyond transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Upstream and downstream of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Immunosuppressive drugs for kidney transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Monitoring of the immunomodulatory effect of CP-690,550 by analysis of the JAK/STAT pathway in kidney transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Calcineurin-inhibitor-free immunosuppression based on the JAK inhibitor CP-690,550: a pilot study in de novo kidney allograft recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Five-year safety and efficacy of belatacept in renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase C and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase C beta enhances growth and expression of cyclin D1 in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Activation of protein kinase C promotes human cancer cell growth through downregulation of p18(INK4c).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

The MARCKS family of phospholipid binding proteins: regulation of phospholipase D and other cellular components

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Involvement of protein kinase C in superoxide anion-induced activation of nuclear factor-kappa B in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase C(theta) in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase C theta affects Ca2+ mobilization and NFAT cell activation in primary mouse T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase C epsilon: a new target to control inflammation and immune-mediated disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

AEB-071 versus tacrolimus monotherapy to prevent acute cardiac allograft rejection in the rat: a preliminary report

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Effects of the new immunosuppressive agent AEB071 on human immune cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

The PKC inhibitor AEB071 may be a therapeutic option for psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Sotrastaurin, a novel small molecule inhibiting protein kinase C: first clinical results in renal-transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Overview of sotrastaurin clinical pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Active drug transport of immunosuppressants: new insights for pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

The effect on sotrastaurin pharmacokinetics of strong CYP3A inhibition by ketoconazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.540238