(Q37818258)

23 August 2017

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title

Gene polymorphisms involved in triptans pharmacokinetics and pharmacodynamics in migraine therapy (English)

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23 August 2017

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6

Paolo Martelletti

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23 August 2017

Giovanna Gentile

1

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23 August 2017

Marina Borro

2

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23 August 2017

Maurizio Simmaco

3

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23 August 2017

Serena Missori

4

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23 August 2017

Noemi Lala

5

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23 August 2017

language of work or name

English

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publication date

11 December 2010

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Expert Opinion on Drug Metabolism & Toxicology

23 August 2017

published in

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23 August 2017

volume

7

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23 August 2017

issue

1

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23 August 2017

page(s)

39-47

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Migraine: a complex genetic disorder

23 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Pathophysiology of migraine chronification

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On serotonin and migraine: a clinical and pharmacological review

21 January 2018

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Serotonin (5-HT) and migraine

21 January 2018

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Dopamine and migraine: biology and clinical implications

21 January 2018

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Mode of action of the anti-migraine drug sumatriptan

21 January 2018

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The discovery of a new drug class for the acute treatment of migraine

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Migraine in the triptan era: progresses achieved, lessons learned and future developments

21 January 2018

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Disruption of communication between peripheral and central trigeminovascular neurons mediates the antimigraine action of 5HT 1B/1D receptor agonists

21 January 2018

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Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Migraine--current understanding and treatment

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Individual triptan selection in migraine attack therapy

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Which triptan for which patient?

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review

21 January 2018

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The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers

21 January 2018

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Identification of the human liver enzymes involved in the metabolism of the antimigraine agent almotriptan

21 January 2018

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The metabolism of zolmitriptan: effects of an inducer and an inhibitor of cytochrome p450 on its pharmacokinetics in healthy volunteers.

21 January 2018

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Safety and efficacy of eletriptan in the treatment of acute migraine

21 January 2018

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Frovatriptan: a review of drug-drug interactions

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Triptan therapy in migraine

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Epilepsy and serotonin (5HT): variations of 5HT-related genes in temporal lobe epilepsy.

21 January 2018

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Further evidence for the association between attention deficit/hyperactivity disorder and the serotonin receptor 1B gene

21 January 2018

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Association of a 5-HT1Dbeta receptor gene polymorphism with obsessive-compulsive disorder in Korean male subjects

21 January 2018

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Polymorphisms in the 5′-untranslated region of the human serotonin receptor 1B (HTR1B) gene affect gene expression

21 January 2018

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Association of a polymorphism of the serotonin 1B receptor gene and alcohol dependence with inactive aldehyde dehydrogenase-2.

21 January 2018

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Suicide, impulsive aggression, and HTR1B genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

The phe-124-Cys and A-161T variants of the human 5-HT1B receptor gene are not major determinants of the clinical response to sumatriptan

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Association study between clinical response to rizatriptan and some candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

5-hydroxytryptamine1B receptor and triptan response in migraine, lack of association with common polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Diplotypes of the human serotonin 1B receptor promoter predict growth hormone responses to sumatriptan in abstinent alcohol-dependent men.

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

The influence of 5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene on treatment effect of selective serotonin reuptake inhibitors in depressive patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Association of the STin2 polymorphism of the serotonin transporter gene with a neurocognitive endophenotype in major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

The serotonin transporter gene polymorphism STin2 VNTR confers an increased risk of inconsistent response to triptans in migraine patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Association of a human G-protein beta3 subunit variant with hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

G protein beta3 polymorphism and triptan response in cluster headache

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Dopamine and migraine: a review of pharmacological, biochemical, neurophysiological, and therapeutic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

New genetic evidence for involvement of the dopamine system in migraine with aura

21 January 2018

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https://api.crossref.org/works/10.1517%2F17425255.2011.538680

A functional polymorphism in the monoamine oxidase A gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Monoamine oxidases A and B gene polymorphisms in migraine patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Frequencies of genetic polymorphisms related to triptans metabolism in chronic migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

21 January 2018

New drugs for migraine

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

What can be learned from the history of recurrence in migraine? A comment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Genetic polymorphism of metabolic enzymes P450 (CYP) as a susceptibility factor for drug response, toxicity, and cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Pharmacokinetics and metabolic drug interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

STin2 VNTR polymorphism in the serotonin transporter gene and migraine: pooled and meta-analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Polymorphism in apolipoprotein E among migraineurs and tension-type headache subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

Lack of association between five serotonin metabolism-related genes and medication overuse headache

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.538680

10.1517/17425255.2011.538680

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference