(Q37828326)

24 August 2017

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title

The mononuclear phagocyte system of the pig as a model for understanding human innate immunity and disease (English)

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24 August 2017

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Ronan Kapetanovic

2

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David A Hume

object named as

David A Hume

series ordinal

4

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author name string

Lynsey Fairbairn

series ordinal

1

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24 August 2017

David P Sester

series ordinal

3

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24 August 2017

publication date

13 January 2011

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Journal of Leukocyte Biology

24 August 2017

published in

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24 August 2017

volume

89

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24 August 2017

issue

6

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24 August 2017

page(s)

855-871

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The mononuclear phagocyte system

24 August 2017

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Inflammation suppressor genes: please switch out all the lights

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MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation

21 January 2018

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MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation

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Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics

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Systems biology of transcription control in macrophages

21 January 2018

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Pattern recognition receptors and inflammation

21 January 2018

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Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells

21 January 2018

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Induction of direct antimicrobial activity through mammalian toll-like receptors

21 January 2018

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Species-specific regulation of Toll-like receptor 3 genes in men and mice.

21 January 2018

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PU.1 and ICSBP control constitutive and IFN-gamma-regulated Tlr9 gene expression in mouse macrophages

21 January 2018

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

21 January 2018

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Developments in CORG: a gene-centric comparative genomics resource

21 January 2018

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ECRbase: database of evolutionary conserved regions, promoters, and transcription factor binding sites in vertebrate genomes

21 January 2018

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Toll-like receptor, MHC II, B7 and cytokine expression by porcine monocytes and monocyte-derived dendritic cells in response to microbial pathogen-associated molecular patterns.

21 January 2018

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Innate immune responses to replication of porcine reproductive and respiratory syndrome virus in isolated Swine alveolar macrophages

21 January 2018

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Gene expression profiling of porcine peripheral blood leukocytes after infection with Actinobacillus pleuropneumoniae

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Swine in biomedical research: creating the building blocks of animal models

21 January 2018

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Porcine myelomonocytic markers and cell populations.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Monocyte and macrophage heterogeneity

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

The EGF-TM7 family: a postgenomic view

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Unravelling mononuclear phagocyte heterogeneity

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Development of monocytes, macrophages, and dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Macrophages as APC and the dendritic cell myth

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Origin and development of dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Porcine Flt3 ligand and its receptor: generation of dendritic cells and identification of a new marker for porcine dendritic cells

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Dendritic cell homeostasis

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Characterization of porcine CD205.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

The mucosal immune system: recent developments and future directions in the pig.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

21 January 2018

Hematopoietic cytokines

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Mouse neutrophilic granulocytes express mRNA encoding the macrophage colony-stimulating factor receptor (CSF-1R) as well as many other macrophage-specific transcripts and can transdifferentiate into macrophages in vitro in response to CSF-1.

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Mice lacking three myeloid colony-stimulating factors (G-CSF, GM-CSF, and M-CSF) still produce macrophages and granulocytes and mount an inflammatory response in a sterile model of peritonitis

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

CSF-1, IGF-1, and the control of postnatal growth and development

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

The molecular basis of pulmonary alveolar proteinosis

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Porcine dendritic cells generated in vitro: morphological, phenotypic and functional properties

21 January 2018

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https://api.crossref.org/works/10.1189%2FJLB.1110607

C-kit positive porcine bone marrow progenitor cells identified and enriched using recombinant stem cell factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Effect of plasmid DNA encoding the porcine granulocyte-macrophage colony-stimulating factor on antigen-presenting cells in pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Granulocyte-macrophage colony stimulating factor promotes prolonged survival and the support of virulent infection by African swine fever virus of macrophages generated from porcine bone marrow and blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Effect of macrophage-specific colony-stimulating factor (CSF-1) on swine monocyte/macrophage susceptibility to in vitro infection by African swine fever virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Selective expansion and continuous culture of macrophages from adult pig blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Comparison of gene expression profiles between human and mouse monocyte subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Colony-stimulating factor-1 (CSF-1) delivers a proatherogenic signal to human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Molecular cloning characterization and expression of porcine immunoreceptor SIRPalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Distribution of anti-CD68 (EBM11) immunoreactivity in formalin-fixed, paraffin-embedded bovine tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Blood monocytes consist of two principal subsets with distinct migratory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The rat macrophage scavenger receptor CD163: expression, regulation and role in inflammatory mediator production

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

In vitro differentiation of porcine blood CD163- and CD163+ monocytes into functional dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Cloning, characterization and mapping of porcine CD14 reveals a high conservation of mammalian CD14 structure, expression and locus organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Molecular cloning, chromosomal location, and expression analysis of porcine CD14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Porcine differential gene expression in response to Salmonella enterica serovars Choleraesuis and Typhimurium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Intracellularly expressed TLR2s and TLR4s contribution to an immunosilent environment at the ocular mucosal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Toll-Like Receptor expressions in porcine alveolar macrophages and Dendritic Cells in responding to poly IC stimulation and porcine reproductive and respiratory syndrome virus (PRRSV) infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Role of MD-2 in TLR2- and TLR4-mediated recognition of Gram-negative and Gram-positive bacteria and activation of chemokine genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Comparative genomics of Toll-like receptor signalling in five species

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Polymorphism distribution and structural conservation in RNA-sensing Toll-like receptors 3, 7, and 8 in pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The evolution of vertebrate Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Cutting edge: species-specific TLR9-mediated recognition of CpG and non-CpG phosphorothioate-modified oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

All three classes of CpG ODNs up-regulate IP-10 gene in pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Toll-like receptor polymorphisms and susceptibility to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Porcine Toll-like receptors: the front line of pathogen monitoring and possible implications for disease resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Functional consequences of toll-like receptor 4 polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Genomic structure, promoter analysis and expression of the porcine (Sus scrofa) TLR4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Toll-like receptor 4 genetic diversity among pig populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The cellular Toll-like receptor 4 antagonist E5531 can act as an agonist in horse whole blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Syk-coupled C-type lectin receptors that mediate cellular activation via single tyrosine based activation motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

C-type lectins and phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Mincle is an ITAM-coupled activating receptor that senses damaged cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The effect of beta-glucans on porcine leukocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Differences in distribution of single nucleotide polymorphisms among intracellular pattern recognition receptors in pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

NOD2 and Crohn's disease: loss or gain of function?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-2 (NOD2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Critical role of NOD2 in regulating the immune response to Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Early immune response following Salmonella enterica subspecies enterica serovar Typhimurium infection in porcine jejunal gut loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Influence of polymorphisms in porcine NOD2 on ligand recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Interferon-inducible Ifi200-family genes in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Alternative activation of macrophages: mechanism and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Macrophage activation and polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Monocyte heterogeneity and innate immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Macrophage receptors and immune recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Interferon-γ: an overview of signals, mechanisms and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Signal integration between IFNgamma and TLR signalling pathways in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Interleukin-8, interleukin-1beta, and interferon-gamma levels are linked to PRRS virus clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Effect of interferon-alpha, interferon-gamma and tumour necrosis factor on African swine fever virus replication in porcine monocytes and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Interferon-induced protection against foot-and-mouth disease virus infection correlates with enhanced tissue-specific innate immune cell infiltration and interferon-stimulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Macrophage polarization in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Quantitative analysis of interleukin-6 expression in porcine spleen cells and alveolar macrophages using real-time PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

African swine fever virus multigene family 360 and 530 genes affect host interferon response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

S100 Calgranulins in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Probing the S100 protein family through genomic and functional analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Of mice and not men: differences between mouse and human immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Defensins: antimicrobial and cytotoxic peptides of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Man is not a mouse: reply

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Macrophage biology and immunology: man is not a mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Quantitative nitric oxide production by rat, bovine and porcine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

IDO expression by dendritic cells: tolerance and tryptophan catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Monitoring tryptophan metabolism in chronic immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Comparative genomics and the study of evolution by natural selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

ImmTree: database of evolutionary relationships of genes and proteins in the human immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Portraits of science. Logic, learning, and experimental medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Adaptive strategies of the influenza virus polymerase for replication in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Advances in swine biomedical model genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

A novel Respiratory Health Score (RHS) supports a role of acute lung damage and pig breed in the course of an Actinobacillus pleuropneumoniae infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Clinical and pathological responses of pigs from two genetically diverse commercial lines to porcine reproductive and respiratory syndrome virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

In vitro susceptibility of macrophages to porcine reproductive and respiratory syndrome virus varies between genetically diverse lines of pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The epidemiology of sepsis in the United States from 1979 through 2000

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The pathogenesis of sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Murine responses to endotoxin: another dirty little secret?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Resilience to bacterial infection: difference between species could be due to proteins in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The disconnect between animal models of sepsis and human sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Inflammatory and circulatory effects of the reduction of endotoxin concentration in established porcine endotoxemic shock--a model of endotoxin elimination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Effects of 15-deoxy-Delta12,14-prostaglandin-J2 during hyperdynamic porcine endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Validation of a Pseudomonas aeruginosa porcine model of septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

A new dynamic porcine model of meningococcal shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Characterization of an animal model of ventilator-acquired pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Lung infections associated with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Detection of cytokine activated chondrocytes in arthritic joints from pigs infected with Erysipelothrix rhusiopathiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Infection of swine with Mycobacterium bovis as a model of human tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Infection of newborn piglets with Bordetella pertussis: a new model for pertussis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Inducible nitric oxide synthase expression in porcine immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Anatomical particularities of the porcine immune system--a physician's view

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Use of alternative animals as asthma models

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

An experimentally induced Chlamydia suis infection in pigs results in severe lung function disorders and pulmonary inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The pig as an experimental model for elucidating the mechanisms governing dietary influence on mineral absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Integrating the immune system with the regulation of growth and efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Rupture of the atherosclerotic plaque: does a good animal model exist?

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The pig as a model for human wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The pig eye as a novel model of glaucoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Spectral attenuation of the mouse, rat, pig and human lenses from wavelengths 360 nm to 1020 nm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Computed tomographic validation of the porcine model for thoracic scoliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Overcoming the barriers to xenotransplantation: prospects for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The PiGMaP consortium linkage map of the pig (Sus scrofa)

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

The pig genome: compositional analysis and identification of the gene-richest regions in chromosomes and nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

In vitro down regulation of proinflammatory cytokines induced by LPS tolerance in pig CD14+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

Suppression of the acute inflammatory response of porcine alveolar‐ and liver macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1110607

21 January 2018

Identifiers

DOI

10.1189/JLB.1110607

1 reference

24 August 2017

1 reference