(Q37844408)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

review article

1 reference

title

The pleiotropic structure of the genotype-phenotype map: the evolvability of complex organisms (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Jianzhi Zhang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

publication date

1 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

published in

Nature Reviews Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

204-213

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21331091%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrg2949

22 January 2020

exact match

0 references

cites work

One hundred years of pleiotropy: a retrospective

1 reference

Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

21 January 2018

1 reference

Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

21 January 2018

1 reference

Common disorders are quantitative traits

21 January 2018

1 reference

Finding the missing heritability of complex diseases

21 January 2018

1 reference

Detecting gene-gene interactions that underlie human diseases

21 January 2018

1 reference

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

21 January 2018

1 reference

Genetic architecture of quantitative traits in mice, flies, and humans

21 January 2018

1 reference

Pleiotropy and the preservation of perfection

21 January 2018

1 reference

Two steps forward, one step back: the pleiotropic effects of favoured alleles.

21 January 2018

1 reference

The evolutionary genetics of canalization

21 January 2018

1 reference

Pleiotropy, Natural Selection, and the Evolution of Senescence

21 January 2018

1 reference

The origins and evolution of genetic disease risk in modern humans

21 January 2018

1 reference

From syndrome families to functional genomics

21 January 2018

1 reference

Pleiotropy as a mechanism to stabilize cooperation

21 January 2018

1 reference

Perspective: Evolutionary developmental biology and the problem of variation

21 January 2018

1 reference

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans

21 January 2018

1 reference

Genomic patterns of pleiotropy and the evolution of complexity

21 January 2018

1 reference

Pleiotropic scaling of gene effects and the 'cost of complexity'.

21 January 2018

1 reference

Mutants highlight the modular control of butterfly eyespot patterns

21 January 2018

1 reference

Genetic dissection of transcriptional regulation in budding yeast

21 January 2018

1 reference

Genetic analysis of genome-wide variation in human gene expression

21 January 2018

1 reference

Catalysis of S-nitrosothiols formation by serum albumin: the mechanism and implication in vascular control

21 January 2018

1 reference

Crystal structure of human serum albumin at 2.5 A resolution

21 January 2018

1 reference

Toward a molecular understanding of pleiotropy

21 January 2018

1 reference

The energetics of genome complexity

21 January 2018

1 reference

The human disease network

21 January 2018

1 reference

The genetics of quantitative traits: challenges and prospects

21 January 2018

1 reference

Perspective: Complex Adaptations and the Evolution of Evolvability

21 January 2018

1 reference

The genetics of adaptation: a reassessment

21 January 2018

1 reference

Fisher's microscope and Haldane's ellipse

21 January 2018

1 reference

A general multivariate extension of Fisher's geometrical model and the distribution of mutation fitness effects across species

21 January 2018

1 reference

Towards a theory of evolutionary adaptation.

21 January 2018

1 reference

Measuring and comparing evolvability and constraint in multivariate characters.

21 January 2018

1 reference

Quantifying organismal complexity using a population genetic approach

21 January 2018

1 reference

A preliminary analysis of gene pleiotropy estimated from protein sequences

21 January 2018

1 reference

Evolutionary framework for protein sequence evolution and gene pleiotropy

21 January 2018

1 reference

21 January 2018

The road to modularity.

1 reference

Pleiotropic scaling and QTL data

21 January 2018

1 reference

Morphological complexity increase in metazoans

21 January 2018

1 reference

The contribution of epistatic pleiotropy to the genetic architecture of covariation among polygenic traits in mice

21 January 2018

1 reference

The genetical theory of natural selection

31 March 2020

1 reference

ADAPTATION AND THE COST OF COMPLEXITY

31 March 2020

1 reference

PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

31 March 2020

1 reference

A global view of pleiotropy and phenotypically derived gene function in yeast

31 March 2020

1 reference

Pleiotropic effects on mandibular morphology II: differential epistasis and genetic variation in morphological integration

31 March 2020

1 reference

PERSPECTIVE: COMPLEX ADAPTATIONS AND THE EVOLUTION OF EVOLVABILITY.

31 March 2020

1 reference

Modularity and the cost of complexity

31 March 2020

1 reference

COMPENSATING FOR OUR LOAD OF MUTATIONS: FREEZING THE MELTDOWN OF SMALL POPULATIONS

31 March 2020

1 reference

FISHER'S MODEL AND THE GENOMICS OF ADAPTATION: RESTRICTED PLEIOTROPY, HETEROGENOUS MUTATION, AND PARALLEL EVOLUTION

31 March 2020

1 reference

Is modularity necessary for evolvability? Remarks on the relationship between pleiotropy and evolvability

31 March 2020

1 reference

Stabilizing selection of protein function and distribution of selection coefficient among sites

31 March 2020

1 reference

The genetics of adaptive shape shift in stickleback: pleiotropy and effect size

31 March 2020

1 reference

12 December 2020

Seven types of pleiotropy.

1 reference

12 December 2020

Effects of pleiotropy on predictions concerning mutation-selection balance for polygenic traits

1 reference

12 December 2020

Pleiotropic models of quantitative variation

1 reference

12 December 2020

Multitrait least squares for quantitative trait loci detection.

1 reference

12 December 2020

Genetic variation in pleiotropy: differential epistasis as a source of variation in the allometric relationship between long bone lengths and body weight.

1 reference

12 December 2020

Common disorders are quantitative traits

1 reference

12 December 2020