(Q37844539)

24 August 2017

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title

Peptidomimetics: modifying peptides in the pursuit of better vaccines (English)

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24 August 2017

Nathan P Croft

1

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Anthony W. Purcell

object named as

Anthony W Purcell

series ordinal

2

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publication date

1 February 2011

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Expert Review of Vaccines

24 August 2017

published in

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24 August 2017

volume

10

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24 August 2017

issue

2

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24 August 2017

page(s)

211-226

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More than one reason to rethink the use of peptides in vaccine design

24 August 2017

cites work

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Peptidomimetics, a synthetic tool of drug discovery

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Epitope-based vaccines: an update on epitope identification, vaccine design and delivery

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Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease

21 January 2018

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Antigenic mimicry of natural L-peptides with retro-inverso-peptidomimetics

21 January 2018

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Recent developments in retro peptides and proteins--an ongoing topochemical exploration

21 January 2018

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Retro-inverso peptidomimetics as new immunological probes. Validation and application to the detection of antibodies in rheumatic diseases

21 January 2018

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The design, synthesis and application of stereochemical and directional peptide isomers: a critical review

21 January 2018

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A rationally designed CD4 analogue inhibits experimental allergic encephalomyelitis

21 January 2018

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Topochemical investigations of peptide systems.

21 January 2018

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Partially modified retro-inverso-enkephalinamides: topochemical long-acting analogs in vitro and in vivo

21 January 2018

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Reversal of peptide backbone direction may result in the mirroring of protein structure

21 January 2018

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A retro-inverso peptide corresponding to the GH loop of foot-and-mouth disease virus elicits high levels of long-lasting protective neutralizing antibodies.

21 January 2018

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Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach

21 January 2018

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Structural comparison between retro-inverso and parent peptides: molecular basis for the biological activity of a retro-inverso analogue of the immunodominant fragment of VP1 coat protein from foot-and-mouth disease virus

21 January 2018

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Solution structure of a retro-inverso peptide analogue mimicking the foot-and-mouth disease virus major antigenic site. Structural basis for its antigenic cross-reactivity with the parent peptide

21 January 2018

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Protection of swine from foot-and-mouth disease with one dose of an all-D retro peptide.

21 January 2018

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A novel retro-inverso gonadotropin-releasing hormone (GnRH) immunogen elicits antibodies that neutralize the activity of native GnRH.

21 January 2018

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Effect of a gonadotropin-releasing hormone vaccine (Improvac) on steroid hormones, boar taint compounds and performance in entire male pigs

21 January 2018

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https://api.crossref.org/works/10.1586%2FERV.10.161

The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2

21 January 2018

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Limitations of Peptide Retro-inverso Isomerization in Molecular Mimicry

21 January 2018

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https://api.crossref.org/works/10.1586%2FERV.10.161

Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

A retro-inverso peptide analogue of influenza virus hemagglutinin B-cell epitope 91-108 induces a strong mucosal and systemic immune response and confers protection in mice after intranasal immunization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

The bare skin and the nose as non-invasive routes for administering peptide vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

H-2Kd-restricted antigenic peptides share a simple binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Exploration of requirements for peptidomimetic immune recognition. Antigenic and immunogenic properties of reduced peptide bond pseudopeptide analogues of a histone hexapeptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Synthesis and antigenic properties of reduced peptide bond analogues of an immunodominant epitope of the melanoma MART-1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Multiple specificities in the repertoire of a melanoma patient's cytolytic T lymphocytes directed against tumor antigen MAGE-1.A1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

A structure-based approach to designing non-natural peptides that can activate anti-melanoma cytotoxic T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Protection against lymphocytic choriomeningitis virus infection induced by a reduced peptide bond analogue of the H-2Db-restricted CD8(+) T cell epitope GP33.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

MSP-1 malaria pseudopeptide analogs: biological and immunological significance and three-dimensional structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Characterization of a reduced peptide bond analogue of a promiscuous CD4 T cell epitope derived from the Plasmodium falciparum malaria vaccine candidate merozoite surface protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Amino acid dimorphism and parasite immune evasion: cellular immune responses to a promiscuous epitope of Plasmodium falciparum merozoite surface protein 1 displaying dimorphic amino acid polymorphism are highly constrained

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

New synthetic non-peptide ligands for classical major histocompatibility complex class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Mimetics of a T cell epitope based on poly-N-acylated amine backbone structures induce T cells in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Synthesis and ex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Binding of rationally designed non-natural peptides to the human leukocyte antigen HLA-B*2705.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Possibilities and limitations in the rational design of modified peptides for T cell mediated immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Limited plasticity in T cell recognition of modified T cell receptor contact residues in MHC class II bound peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-implications for immunological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Peptoids: a modular approach to drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Beta-amino acids: versatile peptidomimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Nonapeptide analogues containing (R)-3-hydroxybutanoate and beta-homoalanine oligomers: synthesis and binding affinity to a class I major histocompatibility complex protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Melanoma peptide MART-1(27-35) analogues with enhanced binding capacity to the human class I histocompatibility molecule HLA-A2 by introduction of a beta-amino acid residue: implications for recognition by tumor-infiltrating lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Terminal modifications inhibit proteolytic degradation of an immunogenic MART-1(27-35) peptide: implications for peptide vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Improvement of the enzymatic stability of a cytotoxic T-lymphocyte-epitope model peptide for its oral administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Antigenic peptides containing large PEG loops designed to extend out of the HLA-A2 binding site form stable complexes with class I major histocompatibility complex molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Treatment of experimental allergic encephalomyelitis (EAE) by a rationally designed cyclic analogue of myelin basic protein (MBP) epitope 72-85.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of Plasmodium falciparum apical membrane antigen 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Exploiting conformationally constrained peptidomimetics and an efficient human-compatible delivery system in synthetic vaccine design

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Design and pre-clinical profiling of a Plasmodium falciparum MSP-3 derived component for a multi-valent virosomal malaria vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Cyclic and dimeric gluten peptide analogues inhibiting DQ2-mediated antigen presentation in celiac disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Non-natural and photo-reactive amino acids as biochemical probes of immune function

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Substituting nonpeptidic spacers for the T cell receptor-binding part of class I major histocompatibility complex-binding peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Rational design of nonnatural peptides as high-affinity ligands for the HLA-B*2705 human leukocyte antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Ficoll and dextran vs. globular proteins as probes for testing glomerular permselectivity: effects of molecular size, shape, charge, and deformability

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Second-generation peptidomimetic inhibitors of antigen presentation effectively treat autoimmune diseases in HLA-DR-transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

SYFPEITHI: database for MHC ligands and peptide motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Mathematical and computational models of immune-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Synthetic anticancer vaccine candidates: rational design of antigenic peptide mimetics that activate tumor-specific T-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Crystal Structures of HLA-A*0201 Complexed with Melan-A/MART-1 26(27L)-35 Peptidomimetics Reveal Conformational Heterogeneity and Highlight Degeneracy of T Cell Recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Attenuated T cell responses to a high-potency ligand in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Transgenic mice with a diverse human T cell antigen receptor repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Peptide Vaccine Induces Enhanced Tumor Growth Associated with Apoptosis Induction in CD8+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Retro-inverso peptide analogues of Trypanosoma cruzi B13 protein epitopes fail to be recognized by human sera and peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

21 January 2018

The IMGT/HLA database

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Proteolytic studies of homologous peptide and N-substituted glycine peptoid oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Antagonistic Effects of Human Cyclic MBP87-99Altered Peptide Ligands in Experimental Allergic Encephalomyelitis and Human T-Cell Proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Role of Optical Isomers in Determining the Antigenicity of Synthetic Polypeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

Induction of T-cell anergy by altered T-cell-receptor ligand on live antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERV.10.161

21 January 2018

Identifiers

DOI

10.1586/ERV.10.161

1 reference

24 August 2017

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