(Q37845397)

24 August 2017

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title

Novel nitric oxide synthase inhibitors: a patent review (English)

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24 August 2017

Jacques Joubert

1

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24 August 2017

Sarel F Malan

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

22 February 2011

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Expert Opinion on Therapeutic Patents

24 August 2017

published in

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24 August 2017

volume

21

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24 August 2017

issue

4

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24 August 2017

page(s)

537-560

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The chemical biology of nitric oxide: implications in cellular signaling

24 August 2017

cites work

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Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

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Nitric oxide: a new paradigm for second messengers.

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Intrinsic and extrinsic modulation of nitric oxide synthase activity.

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Mammalian nitric oxide synthases

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Nitric oxide synthases: structure, function and inhibition

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Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase

21 January 2018

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S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

21 January 2018

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Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2

21 January 2018

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RNA diversity has profound effects on the translation of neuronal nitric oxide synthase

21 January 2018

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Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains

21 January 2018

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Neuronal nitric-oxide synthase-mu, an alternatively spliced isoform expressed in differentiated skeletal muscle

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Cloning of a novel neuronal nitric oxide synthase expressed in penis and lower urinary tract

21 January 2018

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Structural diversity of neuronal nitric oxide synthase mRNA in the nervous system

21 January 2018

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Regulation of neuronal nitric oxide synthase through alternative transcripts

21 January 2018

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Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: evidence for opposing NO actions on morphine analgesia and tolerance

21 January 2018

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Neuronal nitric oxide synthase alternatively spliced forms: prominent functional localizations in the brain

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The protein inhibitor of neuronal nitric oxide synthase (PIN): characterization of its action on pure nitric oxide synthases

21 January 2018

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PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain

21 January 2018

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Targeting eNOS for stroke protection

21 January 2018

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Understanding eNOS for pharmacological modulation of endothelial function: a translational view

21 January 2018

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Computational studies of competitive inhibitors of nitric oxide synthase (NOS) enzymes: towards the development of powerful and isoform-selective inhibitors

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Progress in the development of selective nitric oxide synthase (NOS) inhibitors.

21 January 2018

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Blocking NO synthesis: how, where and why?

21 January 2018

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Inhibition of nitric oxide synthase--potential for a novel class of therapeutic agent?

21 January 2018

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Selective pharmacological inhibition of distinct nitric oxide synthase isoforms

21 January 2018

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Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2

21 January 2018

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Inhibition of rat cerebellar nitric oxide synthase by 7-nitro indazole and related substituted indazoles

21 January 2018

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Two new nitric oxide synthase inhibitors: pyridoxal aminoguanidine and 8-quinolinecarboxylic hydrazide selectively inhibit basal but not agonist-stimulated release of nitric oxide in rat aorta

21 January 2018

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The antinociceptive effect of 1-(2-trifluoromethylphenyl) imidazole (TRIM), a potent inhibitor of neuronal nitric oxide synthase in vitro, in the mouse

21 January 2018

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ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats.

21 January 2018

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Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.

21 January 2018

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Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability

21 January 2018

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Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase

21 January 2018

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Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase

21 January 2018

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21 January 2018

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Nitric oxide in septic shock

21 January 2018

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Inhibition of nitric oxide synthase as a potential therapeutic target

21 January 2018

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1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo

21 January 2018

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GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo

21 January 2018

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3,4-Dihydro-1-isoquinolinamines: a novel class of nitric oxide synthase inhibitors with a range of isoform selectivity and potency

21 January 2018

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1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo

21 January 2018

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Pharmacological interference with dimerization of human neuronal nitric-oxide synthase expressed in adenovirus-infected DLD-1 cells.

21 January 2018

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Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

21 January 2018

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Evidence that inducible nitric oxide synthase is involved in LPS-induced plasma leakage in rat skin through the activation of nuclear factor-kappaB.

21 January 2018

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Endothelial dysfunction: a marker of atherosclerotic risk

21 January 2018

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Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease

21 January 2018

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

21 January 2018

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Multifunctional drugs as neurotherapeutics

21 January 2018

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Design of selective neuronal nitric oxide synthase inhibitors for the prevention and treatment of neurodegenerative diseases

21 January 2018

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[25] Nitric-oxide synthase assays

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.556619

N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.556619

10.1517/13543776.2011.556619

21 January 2018

Identifiers

DOI

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24 August 2017

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