(Q37848484)

24 August 2017

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title

Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells (English)

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24 August 2017

Qian Qi

1

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24 August 2017

Arun Kumar Kannan

series ordinal

2

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24 August 2017

Avery August

series ordinal

3

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24 August 2017

language of work or name

English

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publication date

29 March 2011

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24 August 2017

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24 August 2017

278

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24 August 2017

12

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24 August 2017

1970-1979

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Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/Txk

24 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

ITK inhibitors in inflammation and immune-mediated disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Tec family kinases: regulation of FcεRI-mediated mast-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

TEC-family kinases: regulators of T-helper-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Tec family kinases modulate thresholds for thymocyte development and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Requirements for selection of conventional and innate T lymphocyte lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

21 January 2018

The biology of NKT cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Raising the NKT cell family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

A key role for Itk in both IFN gamma and IL-4 production by NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Differentiation of effector CD4 T cell populations (*)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Calcium signaling in the development and function of T-lineage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

PKCtheta and Itk functionally interact during primary mouse CD3+ T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Development and selection of gammadelta T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

T-cell effector mechanisms: gammadelta and CD1d-restricted subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Recognition of a self major histocompatibility complex TL region product by gamma delta T-cell receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Predominant variable region gene usage by gamma/delta T cell receptor-bearing cells in the adult thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Tec family kinases in T lymphocyte development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Keeping the (kinase) party going: SLP-76 and ITK dance to the beat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent "innate" gammadelta T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Positive selection of dendritic epidermal gammadelta T cell precursors in the fetal thymus determines expression of skin-homing receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

gamma/delta T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

LAT regulates gammadelta T cell homeostasis and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Positive and negative selection invoke distinct signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08074.X

10.1111/J.1742-4658.2011.08074.X

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference