(Q37851350)

24 August 2017

1 reference

title

The tumorigenicity of human embryonic and induced pluripotent stem cells (English)

1 reference

Human Induced Pluripotent Stem Cells

24 August 2017

1 reference

2

Nissim Benvenisty

1 reference

24 August 2017

Uri Ben-David

1

1 reference

PubMed ID

21390058

24 August 2017

language of work or name

English

0 references

publication date

10 March 2011

1 reference

24 August 2017

Nature Reviews Cancer

1 reference

24 August 2017

11

1 reference

24 August 2017

4

1 reference

24 August 2017

268-277

1 reference

https://scigraph.springernature.com/pub.10.1038/nrc3034

24 August 2017

0 references

cites work

Signaling pathways in cancer and embryonic stem cells

1 reference

Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine

31 March 2020

1 reference

The tumorigenicity of human embryonic stem cells

31 March 2020

1 reference

Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture

31 March 2020

1 reference

Embryonic stem cell lines derived from human blastocysts

31 March 2020

1 reference

Adaptation to culture of human embryonic stem cells and oncogenesis in vivo

31 March 2020

1 reference

Culture adaptation of embryonic stem cells echoes germ cell malignancy

31 March 2020

1 reference

Telomere and telomerase in stem cells

31 March 2020

1 reference

31 March 2020

1 reference

Roles of Krüpel-like factor 4 in normal homeostasis, cancer and stem cells

31 March 2020

1 reference

Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors

31 March 2020

1 reference

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

31 March 2020

1 reference

Module map of stem cell genes guides creation of epithelial cancer stem cells

31 March 2020

1 reference

MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states

31 March 2020

1 reference

Cancer genes hypermethylated in human embryonic stem cells

31 March 2020

1 reference

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

31 March 2020

1 reference

CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells

31 March 2020

1 reference

Tumor progression of culture-adapted human embryonic stem cells during long-term culture.

31 March 2020

1 reference

Characterization of human embryonic stem cells with features of neoplastic progression.

31 March 2020

1 reference

The tumorigenicity of diploid and aneuploid human pluripotent stem cells

31 March 2020

1 reference

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

31 March 2020

1 reference

Human embryonic stem cells are prone to generate primitive, undifferentiated tumors in engrafted human fetal tissues in severe combined immunodeficient mice

31 March 2020

1 reference

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

31 March 2020

1 reference

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

31 March 2020

1 reference

Induced pluripotent stem cell lines derived from human somatic cells

31 March 2020

1 reference

Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures

31 March 2020

1 reference

Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells

31 March 2020

1 reference

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

31 March 2020

1 reference

Epigenetic memory in induced pluripotent stem cells

31 March 2020

1 reference

Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells

31 March 2020

1 reference

MYC in oncogenesis and as a target for cancer therapies

31 March 2020

1 reference

The role of Myc-induced protein synthesis in cancer

31 March 2020

1 reference

MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines

31 March 2020

1 reference

Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes

31 March 2020

1 reference

KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines.

31 March 2020

1 reference

Oct-4B isoform is differentially expressed in breast cancer cells: hypermethylation of regulatory elements of Oct-4A suggests an alternative promoter and transcriptional start site for Oct-4B transcription

31 March 2020

1 reference

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

31 March 2020

1 reference

Sox2 protein expression is an independent poor prognostic indicator in stage I lung adenocarcinoma.

31 March 2020

1 reference

Expression of Sox2 in human cervical carcinogenesis.

31 March 2020

1 reference

Embryonic stem cell markers expression in cancers.

31 March 2020

1 reference

iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability.

31 March 2020

1 reference

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

31 March 2020

1 reference

Promotion of direct reprogramming by transformation-deficient Myc.

31 March 2020

1 reference

Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors

31 March 2020

1 reference

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

31 March 2020

1 reference

Reprogramming of human primary somatic cells by OCT4 and chemical compounds

31 March 2020

1 reference

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

31 March 2020

1 reference

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

31 March 2020

1 reference

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

31 March 2020

1 reference

The Ink4/Arf locus is a barrier for iPS cell reprogramming

31 March 2020

1 reference

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

31 March 2020

1 reference

p53: guardian of reprogramming

31 March 2020

1 reference

Telomeres acquire embryonic stem cell characteristics in induced pluripotent stem cells

31 March 2020

1 reference

Reprogramming of telomeric regions during the generation of human induced pluripotent stem cells and subsequent differentiation into fibroblast-like derivatives

31 March 2020

1 reference

Epigenetic regulation of telomeres in human cancer.

31 March 2020

1 reference

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

31 March 2020

1 reference

Generation of pluripotent stem cells from adult mouse liver and stomach cells

31 March 2020

1 reference

Induced pluripotent stem cells generated without viral integration

31 March 2020

1 reference

Generation of mouse induced pluripotent stem cells without viral vectors

31 March 2020

1 reference

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

31 March 2020

1 reference

Human induced pluripotent stem cells free of vector and transgene sequences

31 March 2020

1 reference

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

31 March 2020

1 reference

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

31 March 2020

1 reference

Generation of induced pluripotent stem cells using recombinant proteins

31 March 2020

1 reference

Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins

31 March 2020

1 reference

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

31 March 2020

1 reference

Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells

31 March 2020

1 reference

Culture and characterization of human embryonic stem cells

31 March 2020

1 reference

Genomic alterations in cultured human embryonic stem cells

31 March 2020

1 reference

Human embryonic stem cells reveal recurrent genomic instability at 20q11.21.

31 March 2020

1 reference

Recurrent chromosomal abnormalities in human embryonic stem cells

31 March 2020

1 reference

Comparative genomic hybridization and karyotyping of human embryonic stem cells reveals the occurrence of an isodicentric X chromosome after long-term cultivation

31 March 2020

1 reference

Human embryonic stem cells and genomic instability

31 March 2020

1 reference

High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity

31 March 2020

1 reference

Trisomy 12 in HESC leads to no selective in vivo growth advantage in teratomas, but induces an increased abundance of renal development

31 March 2020

1 reference

Effect of chromosome instability on the maintenance and differentiation of human embryonic stem cells in vitro and in vivo

31 March 2020

1 reference

Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture

31 March 2020

1 reference

An identification of novel therapy for human hepatocellular carcinoma by using human induced pluripotent stem cells

31 March 2020

1 reference

Genetic instability in human induced pluripotent stem cells: classification of causes and possible safeguards.

31 March 2020

1 reference

Molecular analyses of human induced pluripotent stem cells and embryonic stem cells

31 March 2020

1 reference

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

31 March 2020

1 reference

Lab-specific gene expression signatures in pluripotent stem cells

31 March 2020

1 reference

Cancer hallmarks in induced pluripotent cells: new insights

31 March 2020

1 reference

31 March 2020

1 reference

Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation

31 March 2020

1 reference

Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells

31 March 2020

1 reference

Aberrant epigenetic silencing of tumor suppressor genes is reversed by direct reprogramming.

31 March 2020

1 reference

Genomic imprinting and cancer

31 March 2020

1 reference

Genomic imprinting syndromes and cancer.

31 March 2020

1 reference

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

31 March 2020

1 reference

Epigenetic status of human embryonic stem cells.

31 March 2020

1 reference

Status of genomic imprinting in human embryonic stem cells as revealed by a large cohort of independently derived and maintained lines

31 March 2020

1 reference

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative

31 March 2020

1 reference

The effects of culture on genomic imprinting profiles in human embryonic and fetal mesenchymal stem cells

31 March 2020

1 reference

The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming

31 March 2020

1 reference

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

31 March 2020

1 reference

Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1.

31 March 2020

1 reference

Human embryonic stem cells suffer from centrosomal amplification.

31 March 2020

1 reference

Generation of germline-competent induced pluripotent stem cells

31 March 2020

1 reference

c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

31 March 2020

1 reference

Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts

31 March 2020

1 reference

Variation in the safety of induced pluripotent stem cell lines

31 March 2020

1 reference

Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection

31 March 2020

1 reference

Cell therapy and the safety of embryonic stem cell-derived grafts

31 March 2020

1 reference

Effects of cell number on teratoma formation by human embryonic stem cells

31 March 2020

1 reference

Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies.

31 March 2020

1 reference

Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells

31 March 2020

1 reference

Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1.

31 March 2020

1 reference

mAb 84, a cytotoxic antibody that kills undifferentiated human embryonic stem cells via oncosis

31 March 2020

1 reference

Separation of SSEA-4 and TRA-1-60 labelled undifferentiated human embryonic stem cells from a heterogeneous cell population using magnetic-activated cell sorting (MACS) and fluorescence-activated cell sorting (FACS).

31 March 2020

1 reference

The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells.

31 March 2020

1 reference

Myc represses primitive endoderm differentiation in pluripotent stem cells.

31 March 2020

1 reference

myc maintains embryonic stem cell pluripotency and self-renewal

31 March 2020

1 reference

Myc transcription factors: key regulators behind establishment and maintenance of pluripotency.

31 March 2020

1 reference

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

31 March 2020

1 reference

Selective ablation of human embryonic stem cells expressing a "suicide" gene

31 March 2020

1 reference

Stem cell-based therapy for the treatment of Type 1 diabetes mellitus

31 March 2020

1 reference

Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes

31 March 2020

1 reference

Differentiation of encapsulated embryonic stem cells after transplantation.

31 March 2020

1 reference

Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2.

31 March 2020

1 reference

Direct reprogramming of human neural stem cells by OCT4.

31 March 2020

1 reference

Follow the money--the politics of embryonic stem cell research

31 March 2020

1 reference

Copy number variation and selection during reprogramming to pluripotency

31 March 2020

1 reference

Somatic coding mutations in human induced pluripotent stem cells

31 March 2020

1 reference

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

31 March 2020

1 reference

Tumorigenicity of human induced pluripotent stem cells depends on the balance of gene expression between p21 and p53

31 March 2020

1 reference

12 December 2020

An indicator for evaluating the risk of cancerous transformations of human induced pluripotent stem cells

1 reference

12 December 2020

OCT4B1, a novel spliced variant of OCT4, is highly expressed in gastric cancer and acts as an antiapoptotic factor

1 reference

12 December 2020

Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2.

1 reference

12 December 2020

Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3034

1 reference

PubMed ID

21390058

Dimensions Publication ID

24 August 2017

0 references

1 reference

PubMed ID

21390058