(Q37853016)

24 August 2017

1 reference

title

Testicular descent: INSL3, testosterone, genes and the intrauterine milieu (English)

1 reference

24 August 2017

1 reference

1 reference

4

Niels E Skakkebæk

0 references

Jorma Toppari

series ordinal

3

object named as

Jorma Toppari

1 reference

24 August 2017

Katrine Bay

1

1 reference

24 August 2017

Katharina M Main

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

15 March 2011

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24 August 2017

published in

Nature Reviews Urology

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24 August 2017

volume

8

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24 August 2017

issue

4

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24 August 2017

page(s)

187-196

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Fertility after bilateral cryptorchidism. Evaluation by paternity, hormone, and semen data

24 August 2017

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Male pseudohermaphroditism due to a homozygous missense mutation of the luteinizing hormone receptor gene

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Longitudinal reproductive hormone profiles in infants: peak of inhibin B levels in infant boys exceeds levels in adult men.

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Association of impaired phosphatidylinositol 3-kinase activity in GLUT1-containing vesicles with malinsertion of glucose transporters into the plasma membrane of fibroblasts from a patient with severe insulin resistance and clinical features of Wern

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Signalling molecules: clues from development of the limb bud for cryptorchidism?

21 January 2018

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Targeted disruption of the Insl3 gene causes bilateral cryptorchidism

21 January 2018

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Cryptorchidism in mice mutant for Insl3

21 January 2018

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INSL3/Leydig insulin-like peptide activates the LGR8 receptor important in testis descent

21 January 2018

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The role of insulin 3, testosterone, Müllerian inhibiting substance and relaxin in rat gubernacular growth

21 January 2018

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Suppression of insulin-like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development

21 January 2018

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Insulin-like 3 exposure of the fetal rat gubernaculum modulates expression of genes involved in neural pathways

21 January 2018

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Transabdominal testicular descent is disrupted in mice with deletion of insulinlike factor 3 receptor

21 January 2018

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The overexpression of the insl3 in female mice causes descent of the ovaries

21 January 2018

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Insulin-like factor 3 levels in amniotic fluid of human male fetuses.

21 January 2018

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Insulin-like factor 3 levels in second-trimester amniotic fluid

21 January 2018

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AMH and AMH receptor defects in persistent Müllerian duct syndrome

21 January 2018

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Gubernacular development in Müllerian inhibiting substance receptor-deficient mice.

21 January 2018

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Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular development in the complete androgen insensitivity syndrome

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Hormonal control of testicular descent and the cause of cryptorchidism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular position in the androgen insensitivity syndrome: implications for the role of androgens in testicular descent

21 January 2018

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Calcitonin gene-related peptide stimulates mitosis in the tip of the rat gubernaculum in vitro and provides the chemotactic signals to control gubernacular migration during testicular descent

21 January 2018

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Preliminary data suggest that mutations in the CgRP pathway are not involved in human sporadic cryptorchidism

21 January 2018

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The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Antagonistic effects of testosterone and the endocrine disruptor mono-(2-ethylhexyl) phthalate on INSL3 transcription in Leydig cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Insulin-like factor 3 serum levels in 135 normal men and 85 men with testicular disorders: relationship to the luteinizing hormone-testosterone axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Peripheral INSL3 concentrations decline with age in a large population of Australian men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Serum insulin-like factor 3 levels during puberty in healthy boys and boys with Klinefelter syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Relaxin-like factor: a highly specific and constitutive new marker for Leydig cells in the human testis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Paracrine regulation of mammalian oocyte maturation and male germ cell survival

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Expression of the insulin-like peptide 3 (INSL3) hormone-receptor (LGR8) system in the testis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Mutations in the insulin-like factor 3 receptor are associated with osteoporosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

INSL3 has tumor-promoting activity in thyroid cancer

21 January 2018

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THE DESCENT OF THE TESTIS.

21 January 2018

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Difference in prevalence of congenital cryptorchidism in infants between two Nordic countries.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Temporal trends in orchidopexy, Great Britain, 1992-1998

21 January 2018

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The true incidence of cryptorchidism in Denmark.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

International trends in rates of hypospadias and cryptorchidism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Apparent doubling of frequency of undescended testis in England and Wales in 1962-81

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Prevalence of acquired undescended testis in 6-year, 9-year and 13-year-old Dutch schoolboys

21 January 2018

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Nordic consensus on treatment of undescended testes.

21 January 2018

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Cryptorchidism: pathogenesis, diagnosis, treatment and prognosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Risk factors for cryptorchidism and hypospadias

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Familial aggregation of cryptorchidism--a nationwide cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Leydig cell micronodules are a common finding in testicular biopsies from men with impaired spermatogenesis and are associated with decreased testosterone/LH ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular dysgenesis syndrome comprises some but not all cases of hypospadias and impaired spermatogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Increasing incidence of testicular cancer worldwide: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Evidence for decreasing quality of semen during past 50 years

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Decline in semen quality among fertile men in Paris during the past 20 years

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

The question of declining sperm density revisited: an analysis of 101 studies published 1934-1996

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Prevalence of hypospadias in Danish boys: a longitudinal study, 1977-2005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Hypospadias in a cohort of 1072 Danish newborn boys: prevalence and relationship to placental weight, anthropometrical measurements at birth, and reproductive hormone levels at three months of age.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

East-West gradient in semen quality in the Nordic-Baltic area: a study of men from the general population in Denmark, Norway, Estonia and Finland.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Cancer risks in Nordic immigrants and their offspring in Sweden

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular cancer risk in first- and second-generation immigrants to Denmark

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Effects of environmental antiandrogens on reproductive development in experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

A molecular basis for estrogen-induced cryptorchidism.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Pathways of endocrine disruption during male sexual differentiation and masculinization

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

21 January 2018

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Cryptorchidism and hypospadias in sons of gardeners and farmers

21 January 2018

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Human exposure to endocrine-disrupting chemicals and prenatal risk factors for cryptorchidism and hypospadias: a nested case-control study

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Impaired reproductive development in sons of women occupationally exposed to pesticides during pregnancy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Persistent pesticides in human breast milk and cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Maternal pregnancy serum level of heptachlor epoxide, hexachlorobenzene, and beta-hexachlorocyclohexane and risk of cryptorchidism in offspring

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Maternal exposure to a brominated flame retardant and genitourinary conditions in male offspring.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Maternal pregnancy levels of polychlorinated biphenyls and risk of hypospadias and cryptorchidism in male offspring

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Maternal use of acetaminophen, ibuprofen, and acetylsalicylic acid during pregnancy and risk of cryptorchidism

21 January 2018

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Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.

21 January 2018

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Neural tube defects and drinking water disinfection by-products

21 January 2018

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Risk factors for congenital cryptorchidism in a prospective birth cohort study

21 January 2018

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Cryptorchidism and maternal alcohol consumption during pregnancy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Prenatal alcohol exposure and cryptorchidism

21 January 2018

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Alcohol binge drinking during pregnancy and cryptorchidism

21 January 2018

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Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Linkage between cryptorchidism, hypospadias, and GGN repeat length in the androgen receptor gene

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Androgen receptor gene CAG and GGN repeat polymorphisms in Chilean men with primary severe spermatogenic failure

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

A common polymorphism in the human relaxin-like factor (RLF) gene: no relationship with cryptorchidism

21 January 2018

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12 December 2020

Genetic analysis of the INSL3 gene in patients with maldescent of the testis

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Lack of LGR8 gene mutation in Finnish patients with a family history of cryptorchidism

21 January 2018

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T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane

21 January 2018

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Role of hormones, genes, and environment in human cryptorchidism

21 January 2018

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Genetic alterations associated with cryptorchidism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

No association between T222P/LGR8 mutation and cryptorchidism in the Moroccan population

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

The leucine-rich repeat-containing G protein-coupled receptor 8 gene T222P mutation does not cause cryptorchidism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Homeobox HOXA10 gene analysis in cryptorchidism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

21 January 2018

Klinefelter's syndrome

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Male pseudohermaphroditism due to inactivating luteinizing hormone receptor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Country-specific chemical signatures of persistent environmental compounds in breast milk

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Haplotype analysis of the estrogen receptor 1 gene in male genital and reproductive abnormalities.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility

21 January 2018

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Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks

21 January 2018

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Androgen receptor gene CAG and GGC repeat lengths in cryptorchidism

21 January 2018

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Cryptorchidism concordance in monozygotic and dizygotic twin brothers, full brothers, and half-brothers

21 January 2018

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The descriptive epidemiology of congenital and acquired cryptorchidism in a UK infant cohort

21 January 2018

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21 January 2018

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Use of organ culture to study the human fetal testis development: effect of retinoic acid

31 March 2020

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A possible role for reproductive hormones in newborn boys: progressive hypogonadism without the postnatal testosterone peak

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

A biphasic model for the hormonal control of testicular descent

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

The glycosaminoglycans of the gubernaculum during testicular descent in the fetus

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Analysis of testicular migration during the fetal period in humans

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular migration: remodeling of connective tissue and muscle cells in human gubernaculum testis

31 March 2020

1 reference

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Prenatal measurement of testicular diameter by ultrasonography: development of fetal male gender and evaluation of testicular descent

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

A transgenic insertion causing cryptorchidism in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Scanning electron microscopy shows inhibited gubernacular development in relation to undescended testes in oestrogen-treated mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Could testicular descent in humans be promoted by direct androgen stimulation of the gubernaculum testis?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Developmental expression and gene regulation of insulin-like 3 receptor RXFP2 in mouse male reproductive organs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Incidence at birth and natural history of cryptorchidism: a study of 10,730 consecutive male infants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Higher than expected prevalence of congenital cryptorchidism in Lithuania: a study of 1204 boys at birth and 1 year follow-up

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Orchiopexy practice patterns in New York State from 1984 to 2002

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Acquired cryptorchidism is frequent in infancy and childhood

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Maternal, delivery, and perinatal characteristics associated with cryptorchidism: a population-based case-control study among births in Washington State

31 March 2020

1 reference

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Mild gestational diabetes as a risk factor for congenital cryptorchidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Testicular dysgenesis as an etiologic factor in cryptorchidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Prevalence of carcinoma in situ and other histopathological abnormalities in testes of men with a history of cryptorchidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Familial Coaggregation of Cryptorchidism and Hypospadias

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Birth defects among offspring of Norwegian farmers, 1967-1991

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Flame retardants in placenta and breast milk and cryptorchidism in newborn boys

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Cryptorchidism According to Maternal Gestational Smoking

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

The Incidence of Bilateral Cryptorchidism is Increased and the Fertility Potential is Reduced in Sons Born to Mothers who Have Smoked During Pregnancy

31 March 2020

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Familial occurrence of undescended testes

31 March 2020

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Evidence that longer androgen receptor polyglutamine repeats are a causal factor for genital abnormalities

31 March 2020

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CAG repeat length of the androgen receptor gene in Japanese males with cryptorchidism

31 March 2020

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The CAG repeat within the androgen receptor gene and its relationship to cryptorchidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Mutation analysis of INSL3 and GREAT/LGR8 genes in familial cryptorchidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Analysis of homeobox gene HOXA10 mutations in cryptorchidism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2011.23

Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester

31 March 2020

1 reference

12 December 2020

Prevalence and natural history of cryptorchidism

1 reference

12 December 2020

Risk factor patterns for cryptorchidism and hypospadias

1 reference

12 December 2020

Androgen receptor defects: historical, clinical, and molecular perspectives

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12 December 2020

Further insights into the role of T222P variant of RXFP2 in non-syndromic cryptorchidism in two Mediterranean populations

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12 December 2020

The fine structure of possible carcinoma-in-situ in the seminiferous tubules in the testis of four infertile men.

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12 December 2020

THE GUBERNACULUM TESTIS HUNTERI: TESTICULAR DESCENT AND MALDESCENT. ARRIS AND GALE LECTURE DELIVERED AT THE ROYAL COLLEGE OF SURGEONS OF ENGLAND ON 27TH OCTOBER 1959.

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12 December 2020

Testicular cancer incidence in eight northern European countries: secular and recent trends.

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12 December 2020

Human testicular insulin-like factor 3: in relation to development, reproductive hormones and andrological disorders

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12 December 2020

Involution of human fetal Leydig cells. An immunohistochemical, ultrastructural and quantitative study

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12 December 2020

The testicular descent in human. Origin, development and fate of the gubernaculum Hunteri, processus vaginalis peritonei, and gonadal ligaments.

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12 December 2020

The gubernaculum during testicular descent in the human fetus

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12 December 2020

A doubling of morbidity from testis carcinoma in Copenhagen, 1943-1962

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12 December 2020

Male reproductive health and environmental xenoestrogens

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12 December 2020

Effects of orchiopexy on congenitally cryptorchid insulin-3 knockout mice.

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12 December 2020

Identifiers

DOI

10.1038/NRUROL.2011.23

1 reference

24 August 2017

1 reference