(Q37853945)

24 August 2017

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title

Epigenetic markers for chemosensitivity and chemoresistance in pancreatic cancer--a review (English)

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24 August 2017

Sameer Dhayat

1

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24 August 2017

Wolf Arif Mardin

series ordinal

2

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24 August 2017

Soeren Torge Mees

series ordinal

3

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24 August 2017

Joerg Haier

series ordinal

4

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24 August 2017

language of work or name

English

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publication date

18 June 2011

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International Journal of Cancer

24 August 2017

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24 August 2017

129

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24 August 2017

5

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24 August 2017

1031-1041

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24 August 2017

Cancer statistics, 2010

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21 January 2018

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Treatment of advanced pancreatic cancer: from gemcitabine single agent to combinations and targeted therapy.

21 January 2018

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Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer

21 January 2018

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Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomised controlled multicentre phase III trial

21 January 2018

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Origins and Mechanisms of miRNAs and siRNAs

21 January 2018

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MicroRNA expression profiles classify human cancers

21 January 2018

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

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Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells

21 January 2018

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Acquired resistance of pancreatic cancer cells towards 5-Fluorouracil and gemcitabine is associated with altered expression of apoptosis-regulating genes

21 January 2018

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S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer

21 January 2018

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Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

21 January 2018

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Intrinsic chemoresistance to gemcitabine is associated with constitutive and laminin-induced phosphorylation of FAK in pancreatic cancer cell lines

21 January 2018

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CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells

21 January 2018

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HMGA1 is a molecular determinant of chemoresistance to gemcitabine in pancreatic adenocarcinoma

21 January 2018

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RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance

21 January 2018

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Development and characterization of gemcitabine-resistant pancreatic tumor cells.

21 January 2018

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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

21 January 2018

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Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

21 January 2018

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Involvement of ribonucleotide reductase M1 subunit overexpression in gemcitabine resistance of human pancreatic cancer

21 January 2018

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Identifying molecular markers for chemosensitivity to gemcitabine in pancreatic cancer: increased expression of interferon-stimulated gene 15 kd is associated with intrinsic chemoresistance

21 January 2018

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RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine

21 January 2018

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Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells

21 January 2018

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Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer

21 January 2018

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Molecular evidence for increased antitumor activity of gemcitabine by genistein in vitro and in vivo using an orthotopic model of pancreatic cancer

21 January 2018

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Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.

21 January 2018

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Loss of BNIP3 expression is a late event in pancreatic cancer contributing to chemoresistance and worsened prognosis

21 January 2018

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Intrinsic chemoresistance to gemcitabine is associated with decreased expression of BNIP3 in pancreatic cancer

21 January 2018

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Telomerase transcriptional targeting of inducible Bax/TRAIL gene therapy improves gemcitabine treatment of pancreatic cancer

21 January 2018

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Suppression of cFLIP by lupeol, a dietary triterpene, is sufficient to overcome resistance to TRAIL-mediated apoptosis in chemoresistant human pancreatic cancer cells

21 January 2018

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RETRACTED: 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer

21 January 2018

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Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer

21 January 2018

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Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells

21 January 2018

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Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

21 January 2018

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Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells

21 January 2018

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Gemcitabine-based chemogene therapy for pancreatic cancer using Ad-dCK::UMK GDEPT and TS/RR siRNA strategies

21 January 2018

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Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.

21 January 2018

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Chromatin modifier enzymes, the histone code and cancer

21 January 2018

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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21 January 2018

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Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases

21 January 2018

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Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2.

21 January 2018

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Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine).

21 January 2018

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Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells

21 January 2018

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Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

21 January 2018

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HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

21 January 2018

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Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer

21 January 2018

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MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing

21 January 2018

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microPrimer: the biogenesis and function of microRNA.

21 January 2018

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Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

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A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

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RISC is a 5' phosphomonoester-producing RNA endonuclease

21 January 2018

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miRBase: tools for microRNA genomics

21 January 2018

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Epigenetics and microRNAs

21 January 2018

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MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma

21 January 2018

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MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis

21 January 2018

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MicroRNA expression profiles in serous ovarian carcinoma.

21 January 2018

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MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor

21 January 2018

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MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN

21 January 2018

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MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer

21 January 2018

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MicroRNAs: novel diagnostic and therapeutic tools for pancreatic ductal adenocarcinoma?

21 January 2018

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EP300--a miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas

21 January 2018

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Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas

21 January 2018

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Expression profiling identifies microRNA signature in pancreatic cancer

21 January 2018

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MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

21 January 2018

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MicroRNA miR-155 is a biomarker of early pancreatic neoplasia

21 January 2018

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MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease

21 January 2018

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Roles and mechanisms of microRNAs in pancreatic cancer

21 January 2018

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Dysregulation of miR-15a and miR-214 in human pancreatic cancer

21 January 2018

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MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity.

21 January 2018

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Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

21 January 2018

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Antisense inhibition of microRNA-21 or -221 arrests cell cycle, induces apoptosis, and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma

21 January 2018

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Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF

21 January 2018

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Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells

21 January 2018

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MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells

21 January 2018

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MicroRNA-21 is a downstream effector of AKT that mediates its antiapoptotic effects via suppression of Fas ligand

21 January 2018

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Cellular signaling perturbation by natural products

21 January 2018

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Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics

21 January 2018

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Down-regulation of Notch-1 contributes to cell growth inhibition and apoptosis in pancreatic cancer cells.

21 January 2018

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Inhibition of nuclear factor kappab activity by genistein is mediated via Notch-1 signaling pathway in pancreatic cancer cells

21 January 2018

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miR-301a as an NF-κB activator in pancreatic cancer cells

21 January 2018

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Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

21 January 2018

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

21 January 2018

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Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers

21 January 2018

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Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

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Identification of pancreatic cancer stem cells

21 January 2018

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Pancreatic cancer stem cells.

21 January 2018

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ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

21 January 2018

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Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

21 January 2018

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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

21 January 2018

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Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

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Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver

21 January 2018

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LNA-mediated microRNA silencing in non-human primates

21 January 2018

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Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection

21 January 2018

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The let-7 microRNA represses cell proliferation pathways in human cells

21 January 2018

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Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

21 January 2018

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The road toward microRNA therapeutics

21 January 2018

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MicroRNAs: key players in carcinogenesis and novel therapeutic targets.

21 January 2018

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Targeting microRNAs in cancer: rationale, strategies and challenges

21 January 2018

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Implication of microRNAs in drug resistance for designing novel cancer therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.26078

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24 August 2017

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