(Q37854751)

24 August 2017

1 reference

title

The effects of obesity on drug pharmacokinetics in humans (English)

1 reference

24 August 2017

0 references

1 reference

Glynn A Morrish

1

1 reference

24 August 2017

Manjunath P Pai

series ordinal

2

1 reference

24 August 2017

Bruce Green

series ordinal

3

1 reference

24 August 2017

language of work or name

English

0 references

publication date

22 March 2011

1 reference

Expert Opinion on Drug Metabolism & Toxicology

24 August 2017

published in

1 reference

24 August 2017

volume

7

1 reference

24 August 2017

issue

6

1 reference

24 August 2017

page(s)

697-706

1 reference

Obesity and disease management: effects of weight loss on comorbid conditions

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Increases in morbid obesity in the USA: 2000-2005

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Allometric scaling of clearance in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

To scale or not to scale: the principles of dose extrapolation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

What is the best size descriptor to use for pharmacokinetic studies in the obese?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Prediction of hepatic clearance in human from in vitro data for successful drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Effects of obesity on pharmacokinetics implications for drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Perioperative pharmacology in morbid obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Informative study designs to identify true parameter-covariate relationships.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Human organ/tissue growth algorithms that include obese individuals and black/white population organ weight similarities from autopsy data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Organ weight in 684 adult autopsies: new tables for a Caucasoid population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

A statistical analysis of the internal organ weights of normal Japanese people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Quantification of lean bodyweight.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Relationships among liver and kidney volumes, lean body mass and drug clearance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Dosing in obesity: a simple solution to a big problem.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Encouraging the move towards predictive population models for the obese using propofol as a motivating example

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Body mass index as a predictor of hepatic steatosis in living liver donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Prediction of the normal blood volume. Relation of blood volume to body habitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Estimating blood volume in obese and morbidly obese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Relationship between blood pressure, metabolic variables and blood flow in obese subjects with or without non-insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Subcutaneous abdominal adipose tissue blood flow: variation within and between subjects and relationship to obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Comparison of cardiac structure and function in American Indians with and without the metabolic syndrome (the Strong Heart Study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Relations of stroke volume and cardiac output to body composition: the strong heart study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Postnatal growth considerations for PBPK modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Stroke volume and cardiac output in normotensive children and adults. Assessment of relations with body size and impact of overweight

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Relation of various degrees of body mass index in patients with systemic hypertension to left ventricular mass, cardiac output, and peripheral resistance (The Hypertension Genetic Epidemiology Network Study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Hemodynamic monitoring in obese patients: the impact of body mass index on cardiac output and stroke volume.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Predictive performance of 'Servin's formula' during BIS-guided propofol-remifentanil target-controlled infusion in morbidly obese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

The use of propofol and remifentanil for the anaesthetic management of a super-obese patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Individualized compared with conventional dosing of enoxaparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Effect of obesity on the pharmacokinetics of drugs in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Indices of relative weight and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

A standard weight descriptor for dose adjustment in the obese patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Caution when lean body weight is used as a size descriptor for obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

The pharmacokinetics of daptomycin in moderately obese, morbidly obese, and matched nonobese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Influence of morbid obesity on the single-dose pharmacokinetics of daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

The pharmacokinetics and pharmacodynamics of enoxaparin in obese volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Lean body mass as a predictor of drug dosage. Implications for drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Serum protein binding and the role of increased alpha 1-acid glycoprotein in moderately obese male subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Pharmacokinetics and Pharmacodynamics of Triazolam After Two Intermittent Doses in Obese and Normal-Weight Men

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Measured GFR as a confirmatory test for estimated GFR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Influence of weight on aminoglycoside pharmacokinetics in normal weight and morbidly obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Adverse renal consequences of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Expert panel on weight loss surgery: executive report update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Effect of drastic weight loss after bariatric surgery on renal parameters in extremely obese patients: long-term follow-up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Roux-en-Y gastric bypass reverses renal glomerular but not tubular abnormalities in excessively obese diabetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Estimation of creatinine clearance in morbidly obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Role of lean body mass for estimation of glomerular filtration rate in patients with chronic kidney disease with various body mass indices

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Estimating the glomerular filtration rate in obese adult patients for drug dosing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Development of a dosing strategy for enoxaparin in obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

A universal formula based on cystatin C to perform individual dosing of carboplatin in normal weight, underweight, and obese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Pharmacogenetics and human genetic polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Pharmacogenetics of membrane transporters: an update on current approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Drug disposition in obese humans. An update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Biochemical and analytical development of the CIME cocktail for drug fate assessment in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Predictive performance of the 'Minto' remifentanil pharmacokinetic parameter set in morbidly obese patients ensuing from a new method for calculating lean body mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Reduction in hepatic cytochrome P-450 is correlated to the degree of liver fat content in animal models of steatosis in the absence of inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Breast cancer adjuvant chemotherapy dosing in obese patients: dissemination of information from clinical trials to clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Effects of steatosis on drug-metabolizing capability of primary human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.570331

10.1517/17425255.2011.570331

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference