(Q37859337)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

review article

1 reference

title

Regulation of reactive oxygen species in stem cells and cancer stem cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

main subject

reactive oxygen species

1 reference

based on heuristic

inferred from title

neoplastic stem cells

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

Chiharu I Kobayashi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

publication date

1 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular Physiology

27 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

227

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

page(s)

421-430

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity

27 January 2020

cites work

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Inflammation and lung cancer: roles of reactive oxygen/nitrogen species

21 January 2018

1 reference

Mitochondria, oxidants, and aging

21 January 2018

1 reference

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor

21 January 2018

1 reference

Tissue-resident adult stem cell populations of rapidly self-renewing organs

21 January 2018

1 reference

ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage

21 January 2018

1 reference

Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress

21 January 2018

1 reference

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

21 January 2018

1 reference

The impact of O2 availability on human cancer

21 January 2018

1 reference

Epidermal homeostasis: a balancing act of stem cells in the skin

21 January 2018

1 reference

DNA-damage response in tissue-specific and cancer stem cells

21 January 2018

1 reference

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

21 January 2018

1 reference

Regulation of cancer cell metabolism

21 January 2018

1 reference

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.

21 January 2018

1 reference

A side order of stem cells: the SP phenotype

21 January 2018

1 reference

Mitochondria: dynamic organelles in disease, aging, and development

21 January 2018

1 reference

Bcl-2 induces pro-oxidant state by engaging mitochondrial respiration in tumor cells

21 January 2018

1 reference

Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung.

21 January 2018

1 reference

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

21 January 2018

1 reference

Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models

21 January 2018

1 reference

Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

21 January 2018

1 reference

Oxidative stress, redox, and the tumor microenvironment

21 January 2018

1 reference

Expansion of human SCID-repopulating cells under hypoxic conditions

21 January 2018

1 reference

Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation

21 January 2018

1 reference

Association of reactive oxygen species levels and radioresistance in cancer stem cells

21 January 2018

1 reference

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

21 January 2018

1 reference

Oxidants, oxidative stress and the biology of ageing

21 January 2018

1 reference

mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization

21 January 2018

1 reference

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

21 January 2018

1 reference

Making a tumour's bed: glioblastoma stem cells and the vascular niche.

21 January 2018

1 reference

Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo

21 January 2018

1 reference

The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor

21 January 2018

1 reference

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

21 January 2018

1 reference

Hypoxia requires notch signaling to maintain the undifferentiated cell state

21 January 2018

1 reference

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

21 January 2018

1 reference

Redox control and interplay between p53 isoforms: roles in the regulation of basal p53 levels, cell fate, and senescence

21 January 2018

1 reference

Hypoxia inducible factors in cancer stem cells

21 January 2018

1 reference

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

21 January 2018

1 reference

21 January 2018

1 reference

Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.

21 January 2018

1 reference

Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.

21 January 2018

1 reference

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis

21 January 2018

1 reference

CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth

21 January 2018

1 reference

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

21 January 2018

1 reference

PML targeting eradicates quiescent leukaemia-initiating cells

21 January 2018

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A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche

21 January 2018

1 reference

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

21 January 2018

1 reference

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

21 January 2018

1 reference

Interaction between beta-catenin and HIF-1 promotes cellular adaptation to hypoxia

21 January 2018

1 reference

NOX/NADPH Oxidase, the Superoxide-Generating Enzyme: Its Transcriptional Regulation and Physiological Roles

21 January 2018

1 reference

Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice

21 January 2018

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

21 January 2018

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

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The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme

21 January 2018

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Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype

21 January 2018

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Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner

21 January 2018

1 reference

mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.

21 January 2018

1 reference

p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2.

21 January 2018

1 reference

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

21 January 2018

1 reference

Cell-density-dependent regulation of neural precursor cell function.

21 January 2018

1 reference

FIP200 is required for the cell-autonomous maintenance of fetal hematopoietic stem cells

21 January 2018

1 reference

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

21 January 2018

1 reference

O2 regulates stem cells through Wnt/β-catenin signalling.

21 January 2018

1 reference

Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro.

21 January 2018

1 reference

Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress

21 January 2018

1 reference

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation.

21 January 2018

1 reference

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

21 January 2018

1 reference

Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells

21 January 2018

1 reference

TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

21 January 2018

1 reference

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

21 January 2018

1 reference

Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

21 January 2018

1 reference

Hematopoiesis: an evolving paradigm for stem cell biology

21 January 2018

1 reference

Stem cell aging is controlled both intrinsically and extrinsically in the Drosophila ovary

21 January 2018

1 reference

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

21 January 2018

1 reference

Lipid peroxidation, total antioxidant status, and total thiol levels predict overall survival in patients with oral squamous cell carcinoma

21 January 2018

1 reference

Oxidative stress regulation of stem and progenitor cells

21 January 2018

1 reference

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation

21 January 2018

1 reference

Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity.

21 January 2018

1 reference

A model for p53-induced apoptosis

21 January 2018

1 reference

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal

21 January 2018

1 reference

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha

21 January 2018

1 reference

Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice.

21 January 2018

1 reference

Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho.

21 January 2018

1 reference

The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

21 January 2018

1 reference

Tracking adult stem cells.

21 January 2018

1 reference

Forkhead homeobox type O transcription factors in the responses to oxidative stress

21 January 2018

1 reference

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

21 January 2018

1 reference

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

21 January 2018

1 reference

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

21 January 2018

1 reference

Premeiotic germ cell defect in seminiferous tubules of Atm-null testis.

21 January 2018

1 reference

Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest

21 January 2018

1 reference

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

21 January 2018

1 reference

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

21 January 2018

1 reference

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

21 January 2018

1 reference

Functional interaction between FOXO3a and ATM regulates DNA damage response

21 January 2018

1 reference

Role of nox2-based NADPH oxidase in bone marrow and progenitor cell function involved in neovascularization induced by hindlimb ischemia

21 January 2018

1 reference

Stressing the role of FoxO proteins in lifespan and disease

21 January 2018

1 reference

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

21 January 2018

1 reference

Cellular and molecular signatures of muscle regeneration: current concepts and controversies in adult myogenesis

21 January 2018

1 reference

On the Origin of Cancer Cells

21 January 2018

1 reference

Detection of functional haematopoietic stem cell niche using real-time imaging.

21 January 2018

1 reference

Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.

21 January 2018

1 reference

ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice.

21 January 2018

1 reference

Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells

21 January 2018

1 reference

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

1 reference

Stem cells in mammalian spermatogenesis.

21 January 2018

1 reference

Mechanisms and functional implications of adult neurogenesis

21 January 2018

1 reference

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

21 January 2018

1 reference

In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.22764

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21448925%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference