(Q37860139)

English

Caspases and cancer

scientific article published on April 2011

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scholarly article

1 reference

Europe PubMed Central

24 August 2017

1 reference

Europe PubMed Central

Caspases and cancer (English)

1 reference

Europe PubMed Central

24 August 2017

object named as

M Olsson

1

0 references

Boris Zhivotovsky

object named as

B Zhivotovsky

2

0 references

publication date

1 April 2011

1 reference

Europe PubMed Central

24 August 2017

Cell Death & Differentiation

1 reference

Europe PubMed Central

24 August 2017

18

1 reference

Europe PubMed Central

24 August 2017

1441-1449

1 reference

Europe PubMed Central

24 August 2017

9

1 reference

Europe PubMed Central

24 August 2017

https://scigraph.springernature.com/pub.10.1038/cdd.2011.30

0 references

Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo

1 reference

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6 September 2017

Mitochondria and cell death: outer membrane permeabilization and beyond

1 reference

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The Yin and Yang functions of the Myc oncoprotein in cancer development and as targets for therapy

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6 September 2017

Caspase 2-mediated tumor suppression involves survivin gene silencing

1 reference

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6 September 2017

NF-kappaB and cancer: how intimate is this relationship

1 reference

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6 September 2017

Survivin as a global target of intrinsic tumor suppression networks

1 reference

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6 September 2017

Apoptosis and cancer: mutations within caspase genes

1 reference

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6 September 2017

Critical role for caspase-8 in epidermal growth factor signaling

1 reference

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6 September 2017

A tumor suppressor function for caspase-2

1 reference

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6 September 2017

Gene polymorphisms, apoptotic capacity and cancer risk

1 reference

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6 September 2017

DNA-PKcs-PIDDosome: a nuclear caspase-2-activating complex with role in G2/M checkpoint maintenance

1 reference

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6 September 2017

TAp73beta and DNp73beta activate the expression of the pro-survival caspase-2S

1 reference

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6 September 2017

Genetic variants and haplotypes of the caspase-8 and caspase-10 genes contribute to susceptibility to cutaneous melanoma

1 reference

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6 September 2017

Caspase-8: fly or die.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Does caspase inhibition promote clonogenic tumor growth?

1 reference

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6 September 2017

Are promyelocytic leukaemia protein nuclear bodies a scaffold for caspase-2 programmed cell death?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

The CASBAH: a searchable database of caspase substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

ATM and breast cancer susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Targeting XIAP for the treatment of malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Unique and overlapping substrate specificities of caspase-8 and caspase-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Molecular pathogenesis of follicular lymphoma: a cross talk of genetic and immunologic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Cell division and cell survival in the absence of survivin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Upregulation of survivin in G2/M cells and inhibition of caspase 9 activity enhances resistance in staurosporine-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Hypermethylation of XIAP-associated factor 1, a putative tumor suppressor gene from the 17p13.2 locus, in human gastric adenocarcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Caspase-8 and caspase-10 activate NF-kappaB through RIP, NIK and IKKalpha kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

A unified model for apical caspase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Caspase-10 is an initiator caspase in death receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Caspase-2 pre-mRNA alternative splicing: Identification of an intronic element containing a decoy 3' acceptor site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Activation of the NF-kappaB pathway by caspase 8 and its homologs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Activation of NF-kappaB by FADD, Casper, and caspase-8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

6 September 2017

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

14 September 2017

Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

14 September 2017

Silibinin activates p53-caspase 2 pathway and causes caspase-mediated cleavage of Cip1/p21 in apoptosis induction in bladder transitional-cell papilloma RT4 cells: evidence for a regulatory loop between p53 and caspase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

14 September 2017

Inactivating mutations of the caspase-10 gene in gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

28 September 2017

Death effector domain-only polypeptides of caspase-8 and -10 specifically inhibit death receptor-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

28 September 2017

Caspase 7 downregulation as an immunohistochemical marker of colonic carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

28 September 2017

Molecular cloning and characterization of a novel caspase-3 variant that attenuates apoptosis induced by proteasome inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

28 September 2017

Resistance to caspase-independent cell death requires persistence of intact mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

28 September 2017

DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Caspase-8 deficiency facilitates cellular transformation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

A promoter polymorphism in the CASP8 gene is not associated with cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Evaluation of the role of caspase-6 in anticancer drug-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Association of the CASP10 V410I variant with reduced familial breast cancer risk and interaction with the CASP8 D302H variant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Caspase 8 is absent or low in many ex vivo gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Caspase-8L expression protects CD34+ hematopoietic progenitor cells and leukemic cells from CD95-mediated apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

CASPASE-8 gene is inactivated by somatic mutations in gastric carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Downregulation of Smac/DIABLO expression in renal cell carcinoma and its prognostic significance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Loss of caspase-2, -6 and -7 expression in gastric cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Fas A670G polymorphism, apoptotic capacity in lymphocyte cultures, and risk of lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Inactivating mutations of CASPASE-7 gene in human cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Inactivating mutations of caspase-8 gene in colorectal carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Caspase 3 in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

1 September 2018

A common coding variant in CASP8 is associated with breast cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178435

3 December 2018

Immunohistochemical expression of caspase-3 as an adverse indicator of the clinical outcome in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic significance of overexpression of the decoy receptor for Fas ligand (DcR3) in patients with gastric carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of caspase-3s splice variant in locally advanced breast carcinoma is associated with poor response to neoadjuvant chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apaf-1 and caspase-9 deficiency prevents apoptosis in a Bax-controlled pathway and promotes clonogenic survival during paclitaxel treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21455218

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of adhesion molecules and Ki-67 in female adnexal tumor of probable Wolffian origin (FATWO): report of two cases and review of the literature.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2011.30

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CDD.2011.30

1 reference

Europe PubMed Central

24 August 2017

1 reference

Europe PubMed Central

24 August 2017

1 reference

Europe PubMed Central

24 August 2017

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