(Q37863134)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

review article

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title

Cell death and nonalcoholic steatohepatitis: where is ballooning relevant? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

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2

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28 January 2020

author name string

Mariana Verdelho Machado

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

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1 April 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

Expert Review of Gastroenterology & Hepatology

28 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

5

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28 January 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

213-222

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

Steatohepatitis: a tale of two "hits"?

28 January 2020

cites work

1 reference

Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

21 January 2018

1 reference

Mechanisms of disease progression in nonalcoholic fatty liver disease

21 January 2018

1 reference

Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study

21 January 2018

1 reference

The clinical utility of biomarkers and the nonalcoholic steatohepatitis CRN liver biopsy scoring system in patients with nonalcoholic fatty liver disease.

21 January 2018

1 reference

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

21 January 2018

1 reference

Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease

21 January 2018

1 reference

Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity

21 January 2018

1 reference

Long-term follow-up of patients with NAFLD and elevated liver enzymes

21 January 2018

1 reference

Cell death by necrosis: towards a molecular definition

21 January 2018

1 reference

Autophagy in liver diseases.

21 January 2018

1 reference

Apoptosis and necrosis in liver disease

21 January 2018

1 reference

Apoptosis and necrosis in the liver: a tale of two deaths?

21 January 2018

1 reference

Dying a thousand deaths: redundant pathways from different organelles to apoptosis and necrosis

21 January 2018

1 reference

Apoptosis: a review of programmed cell death

21 January 2018

1 reference

Apoptosis in alcoholic and nonalcoholic steatohepatitis

21 January 2018

1 reference

Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response

21 January 2018

1 reference

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

Histopathology of non-alcoholic fatty liver disease

21 January 2018

1 reference

Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis

21 January 2018

1 reference

Apoptosis markers in liver biopsy of nonalcoholic steatohepatitis in pediatric patients

21 January 2018

1 reference

Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver

21 January 2018

1 reference

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis

21 January 2018

1 reference

Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression.

21 January 2018

1 reference

Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

21 January 2018

1 reference

Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice

21 January 2018

1 reference

Enhanced sensitivity to CD95-induced apoptosis in ob/ob mice

21 January 2018

1 reference

Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver

21 January 2018

1 reference

Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity

21 January 2018

1 reference

Beyond insulin resistance in NASH: TNF-alpha or adiponectin?

21 January 2018

1 reference

p53 involvement in the pathogenesis of fatty liver disease.

21 January 2018

1 reference

Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease

21 January 2018

1 reference

In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases

21 January 2018

1 reference

Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling.

21 January 2018

1 reference

Death receptors: signaling and modulation

21 January 2018

1 reference

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

21 January 2018

1 reference

Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss

21 January 2018

1 reference

21 January 2018

1 reference

Mechanisms and clinical implications of hepatocyte lipoapoptosis

21 January 2018

1 reference

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

21 January 2018

1 reference

Endoplasmic reticulum stress in liver disease

21 January 2018

1 reference

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

21 January 2018

1 reference

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance

21 January 2018

1 reference

Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER.

21 January 2018

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Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

21 January 2018

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Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells

21 January 2018

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CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis

21 January 2018

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Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury

21 January 2018

1 reference

Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion

21 January 2018

1 reference

Autophagy regulates lipid metabolism

21 January 2018

1 reference

ER-phagy: selective autophagy of the endoplasmic reticulum.

21 January 2018

1 reference

Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice.

21 January 2018

1 reference

Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications

21 January 2018

1 reference

Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

21 January 2018

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Hepatic autophagy is suppressed in the presence of insulin resistance and hyperinsulinemia: inhibition of FoxO1-dependent expression of key autophagy genes by insulin

21 January 2018

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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

21 January 2018

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Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

21 January 2018

1 reference

Hepatocellular ballooning in NASH.

21 January 2018

1 reference

From Mallory to Mallory-Denk bodies: what, how and why?

21 January 2018

1 reference

Autophagy is involved in the elimination of intracellular inclusions, Mallory-Denk bodies, in hepatocytes

21 January 2018

1 reference

21 January 2018

Mallory bodies revisited

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In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62.

21 January 2018

1 reference

Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies.

21 January 2018

1 reference

Switch in Fas-activated death signaling pathway as result of keratin 8/18-intermediate filament loss.

21 January 2018

1 reference

Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation

21 January 2018

1 reference

Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies

21 January 2018

1 reference

Colchicine protects mice from the lethal effect of an agonistic anti-Fas antibody

21 January 2018

1 reference

Dual roles of intermediate filaments in apoptosis

21 January 2018

1 reference

Susceptibility to hepatotoxicity in transgenic mice that express a dominant-negative human keratin 18 mutant

21 January 2018

1 reference

Novel insights into changes in biochemical properties of keratins 8 and 18 in griseofulvin-induced toxic liver injury

21 January 2018

1 reference

Intersection of the unfolded protein response and hepatic lipid metabolism

21 January 2018

1 reference

Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates

21 January 2018

1 reference

Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression

21 January 2018

1 reference

Hepatocyte Apoptosis, Expression of Death Receptors, and Activation of NF-κB in the Liver of Nonalcoholic and Alcoholic Steatohepatitis Patients

21 January 2018

1 reference

Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis

21 January 2018

1 reference

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EGH.11.16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21476916%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference