(Q37863679)

24 August 2017

1 reference

title

Assays and applications in warfarin metabolism: what we know, how we know it and what we need to know (English)

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24 August 2017

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Drew R Jones

1

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24 August 2017

Grover P Miller

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

12 April 2011

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Expert Opinion on Drug Metabolism & Toxicology

24 August 2017

published in

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24 August 2017

volume

7

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24 August 2017

issue

7

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24 August 2017

page(s)

857-874

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Pharmacology and management of the vitamin K antagonists: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Bleeding complications with warfarin use: a prevalent adverse effect resulting in regulatory action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Synthesis and structure-activity relationships of novel warfarin derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Vitamin K and the oral anticoagulant drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Warfarin metabolism in man: identification of metabolites in urine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Human P450 metabolism of warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Cytochrome P4502C9: an enzyme of major importance in human drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Determination of warfarin enantiomers and hydroxylated metabolites in human blood plasma by liquid chromatography with achiral and chiral separation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Warfarin therapy: how the less interesting half just got interesting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

VKORC1 gene variations are the major contributors of variation in warfarin dose in Japanese patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Liquid Chromatographic Assay of Warfarin: Similarity of Warfarin Half-Lives in Human Subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

GLC determination of warfarin in human plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Disposition of warfarin enantiomers and metabolites in patients during multiple dosing with rac-warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Warfarin and Warfarin-Alcohol Levels in Anticoagulated Patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Determination of phenprocoumon, warfarin and their monohydroxylated metabolites in human plasma and urine by liquid chromatography-mass spectrometry after solid-phase extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Analysis of oxidative warfarin metabolites by thermospray high-performance liquid chromatography/mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography-tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

The assay of warfarin in plasma or stool.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Warfarin. Stereochemical aspects of its metabolism and the interaction with phenylbutazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Quantitative liquid chromatography/mass spectrometry/mass spectrometry warfarin assay for in vitro cytochrome P450 studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Determination of plasma warfarin concentrations in Korean patients and its potential for clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

A pilot study of the association of pharmacokinetic and pharmacodynamic parameters of warfarin with the dose in patients on long-term anticoagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

CYP2C9 gene variants, drug dose, and bleeding risk in warfarin-treated patients: a HuGEnet systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Association of warfarin dose with genes involved in its action and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Integration of genetic, clinical, and INR data to refine warfarin dosing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Warfarin as a probe of cytochromes P-450 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Effect of a triphasic oral contraceptive on drug-metabolizing enzyme activity as measured by the validated Cooperstown 5+1 cocktail

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Warfarin and UDP-glucuronosyltransferases: writing a new chapter of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Reaction phenotyping: current industry efforts to identify enzymes responsible for metabolizing drug candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Use of microdosing to predict pharmacokinetics at the therapeutic dose: experience with 5 drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

In silico pharmacogenetics of warfarin metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

High-Pressure Liquid Chromatographic Analysis of drugs in Biological Fluids I: Warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.576247

10.1517/17425255.2011.576247

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference