Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37864818)
Watch
English
Toward mechanistic classification of enzyme functions
scientific article published on 12 April 2011
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Toward mechanistic classification of enzyme functions
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
author
Patricia Babbitt
series ordinal
2
object named as
Patricia C Babbitt
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
Daniel E Almonacid
object named as
Daniel E Almonacid
series ordinal
1
0 references
publication date
12 April 2011
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
published in
Current Opinion in Chemical Biology
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
volume
15
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
page(s)
435-442
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
cites work
The structures and physicochemical properties of organic cofactors in biocatalysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
The CoFactor database: organic cofactors in enzyme catalysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Mechanistic similarity and diversity among the guanidine-modifying members of the pentein superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes: implications for classification of enzyme function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Small Molecule Subgraph Detector (SMSD) toolkit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Automatic assignment of EC numbers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Markers of fitness in a successful enzyme superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Aldo-keto reductase (AKR) superfamily: genomics and annotation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
A mapping of drug space from the viewpoint of small molecule metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Annotating Enzymes of Uncertain Function: The Deacylation of d -Amino Acids by Members of the Amidohydrolase Superfamily ,
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Functional Annotation of Two New Carboxypeptidases from the Amidohydrolase Superfamily of Enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Using sequence similarity networks for visualization of relationships across diverse protein superfamilies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Retroviral integrase superfamily: the structural perspective
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Functional Annotation and Three-Dimensional Structure of Dr0930 from Deinococcus radiodurans , a Close Relative of Phosphotriesterase in the Amidohydrolase Superfamily † ‡
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
AnEnPi: identification and annotation of analogous enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Evolutionarily conserved substrate substructures for automated annotation of enzyme superfamilies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
A Protein Structure (or Function ?) Initiative.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Evolution of enzyme superfamilies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Hierarchical classification of hydrolases catalytic sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Leveraging enzyme structure-function relationships for functional inference and experimental design: the structure-function linkage database
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Charting biologically relevant chemical space: a structural classification of natural products (SCONP)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
EzCatDB: the Enzyme Catalytic-mechanism Database
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
SCOPEC: a database of protein catalytic domains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
PDBSprotEC: a Web-accessible database linking PDB chains to EC numbers via SwissProt
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
A structure-based anatomy of the E.coli metabolome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Definitions of enzyme function for the structural genomics era.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Maximum common subgraph isomorphism algorithms for the matching of chemical structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Divergent evolution of enzymatic function: mechanistically diverse superfamilies and functionally distinct suprafamilies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
SCOP: a structural classification of proteins database for the investigation of sequences and structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
Enzyme recruitment in evolution of new function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
6 September 2017
On the origin of enzymatic species
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
28 September 2017
Convergent evolution of enzyme active sites is not a rare phenomenon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
28 September 2017
Bacterial ammeline metabolism via guanine deaminase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
23 June 2018
Using reaction mechanism to measure enzyme similarity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
23 June 2018
Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
23 June 2018
Relationships between functional subclasses and information contained in active-site and ligand-binding residues in diverse superfamilies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Similarity perception of reactions catalyzed by oxidoreductases and hydrolases using different classification methods.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Mapping human metabolic pathways in the small molecule chemical space.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Automatic assignment of reaction operators to enzymatic reactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Assignment of EC numbers to enzymatic reactions with MOLMAP reaction descriptors and random forests.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
E-zyme: predicting potential EC numbers from the chemical transformation pattern of substrate-product pairs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Understanding the functional roles of amino acid residues in enzyme catalysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Investigations of enzyme-catalyzed reactions based on physicochemical descriptors applied to hydrolases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Genome-scale classification of metabolic reactions and assignment of EC numbers with self-organizing maps.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Metal ions in biological catalysis: from enzyme databases to general principles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
The chemistry of protein catalysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
PROCOGNATE: a cognate ligand domain mapping for enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
A ligand-centric analysis of the diversity and evolution of protein-ligand relationships in E.coli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Catalysing new reactions during evolution: economy of residues and mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
1 September 2018
Metal-MACiE: a database of metals involved in biological catalysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3551611
retrieved
3 December 2018
Systematic comparison of catalytic mechanisms of hydrolysis and transfer reactions classified in the EzCatDB database
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21489855
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Genome-wide analysis of enzyme structure-function combination across three domains of life
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21489855
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CBPA.2011.03.008
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
PMCID
3551611
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
PubMed ID
21489855
1 reference
stated in
Europe PubMed Central
PMCID
3551611
retrieved
24 August 2017
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
