(Q37869470)

24 August 2017

1 reference

title

Determining the chemical mechanisms of enzyme-catalyzed reactions by kinetic studies (English)

2 references

24 August 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21524

19 March 2022

author name string

W. W. Cleland

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21524

19 March 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21524

19 March 2022

publication date

1 January 1977

1 reference

full work available at URL

24 August 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F9780470122907.ch4

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

https://onlinelibrary.wiley.com/doi/full/10.1002/9780470122907.ch4

19 March 2022

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Advances in Enzymology and Related Areas of Molecular Biology

19 March 2022

published in

1 reference

24 August 2017

45

1 reference

24 August 2017

273-387

1 reference

Partition analysis and concept of net rate constants as tools in enzyme kinetics

24 August 2017

5

14

3220

Cleland

1975

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Determination of the rate-limiting steps for malic enzyme by the use of isotope effects and other kinetic studies

19 March 2022

9

16

571

Schimerlik

1977

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetics of dithionite ion utilization and ATP hydrolysis for reactions catalyzed by the nitrogenase complex from Azotobacter vinelandii

19 March 2022

10

16

264

Watt

1977

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

On the mechanism of action of fructose 1,6-diphosphatase. Inhibition by structural analogs of fructose 1,6-diphosphate.

19 March 2022

16

10

4881

Benkovic

1971

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Preparation and properties of chromium (3)-nucleotide complexes for use in the study of enzyme mechanisms

19 March 2022

17

12

3714

DePamphilis

1973

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Use of chromium-adenosine triphosphate and lyxose to elucidate the kinetic mechanism and coordination state of the nucleotide substrate for yeast hexokinase

19 March 2022

20

14

28

Danenberg

1975

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Use of isotope competition and alternative substrates for studying the kinetic mechanism of enzyme action. I. Experiments with hexokinase and alcohol dehydroeenase.

19 March 2022

21

9

4660

Rudolph

1970

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

19 March 2022

22

67

173

Cleland

1963

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Evaluation of the phosphoryl-enzyme intermediate concept in the acetate kinase and hexokinase reactions from kinetic studies.

19 March 2022

23

149

307

Purich

1972

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The mechanism of the reaction catalysed by adenosine triphosphate-creatine phosphotransferase

19 March 2022

24

97

37

Morrison

0 references

The kinetics of enzyme-catalyzed reactions with two or more substrates or products

27

67

104

Cleland

1963

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Inhibition and alternate-substrate studies on the mechanism of malic enzyme

19 March 2022

29

16

565

Schimerlik

1977

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The Effect of Structural Modifications of ATP on the Yeast-Hexokinase Reaction

19 March 2022

33

31

180

Hohnadel

1973

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Inhibition of hexokinase by multisubstrate analogs

19 March 2022

34

480

351

Danenberg

1977

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Reaction parameters and order of substrate addition

19 March 2022

37

10

4804

Santi

1971

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The kinetics and mechanism of liver alcohol dehydrogenase with primary and secondary alcohols as substrates

19 March 2022

38

100

34

Dalziel

1966

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The use of competitive inhibitors in studying the mechanism of action of some enzyme systems utilizing three substrates

19 March 2022

41

139

221

Fromm

1967

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

STUDIES ON LIVER ALCOHOL HYDROGENASE COMPLEXES. 3. MULTIPLE INHIBITION KINETICS IN THE PRESENCE OF TWO COMPETITIVE INHIBITORS

19 March 2022

43

106

243

Yonetani

1964

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange.

19 March 2022

45

29

620

Santi

1974

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetic studies of Escherichia coli galactokinase

19 March 2022

53

7

566

Gulbinsky

1968

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Steady-state analysis of kinetic isotope effects in enzymic reactions

19 March 2022

56

14

2644

Northrop

1975

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Equilibrium perturbation by isotope substitution

19 March 2022

59

14

5347

Schimerlik

1975

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Deuterium isotope effects on initial rates of the liver alcohol dehydrogenase reaction

19 March 2022

63

12

4802

Bush

1973

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Fumarase activity in deuterium oxide

19 March 2022

66

90

1

Thomson

1960

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The pH variation of the kinetic parameters and the catalytic mechanism of malic enzyme

19 March 2022

69

16

576

Schimerlik

1977

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group

19 March 2022

70

14

5274

Hartman

1975

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

pH-dependence of the triose phosphate isomerase reaction

19 March 2022

71

129

311

Plant

1972

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Purification and mechanism of action of proline racemase

19 March 2022

72

7

3970

Cardinale

1968

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Mechanism of the .alpha.-chymotrypsin-catalyzed hydrolysis of specific amide substrates

19 March 2022

73

94

293

Fersht

1972

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Triosephosphate isomerase: isotope studies on the mechanistic pathway

19 March 2022

74

36

157

Knowles

1971

0 references

Secondary isotope effects in the dehydration of malic acid by fumarate hydratase

75

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Divalent cation and pH-dependent primary isotope effects in the enolase reaction

19 October 2022

79

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Nuclear relaxation and kinetic studies of the role of Mn 2+ in the mechanism of enolase

19 October 2022

83

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Isotope and solvent effects of deuterium on aconitase

19 October 2022

86

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5Å resolution: using amino acid sequence data

19 October 2022

87

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The amino acid sequence of rabbit muscle triose phosphate isomerase

19 October 2022

88

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Haloacetol phosphates. Characterization of the active site of rabbit muscle triose phosphate isomerase

19 October 2022

89

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The active centre of rabbit muscle triose phosphate isomerase. The site that is labelled by glycidol phosphate

19 October 2022

90

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Active-site labelling of triose phosphate isomerase. The reaction of bromohydroxyacetone phosphate with a unique glutamic acid residue and the migration of the label to tyrosine

19 October 2022

91

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The pK of the carboxyl group at the active centre of triose phosphate isomerase

19 October 2022

92

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The free energy of hydrolysis of the phosphoryl-enzyme intermediate in alkaline phosphatase catalyzed reactions

19 October 2022

95

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The active site and mechanism of action of bovine pancreatic ribonuclease. 5. The charge types at the active centre

19 October 2022

96

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The active site and mechanism of action of bovine pancreatic ribonuclease. 7. The catalytic mechanism

19 October 2022

98

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Cobalt(III) carboxypeptidase A

19 October 2022

101

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetics and electron paramagnetic resonance spectra of vanadyl(IV) carboxypeptidase A.

19 October 2022

102

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Carboxypeptidase A. Differences in the mechanisms of ester and peptide hydrolysis

19 October 2022

103

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Nuclear magnetic resonance study of the binding of fluoride ions to carboxypeptidase A

19 October 2022

104

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Mechanism of action of carboxypeptidase A in ester hydrolysis

19 October 2022

105

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Effect of D2O on the carboxypeptidase-catalyzed hydrolysis of O-(trans-cinnamoyl)-L-beta-phenyllactate and N-(N-benzoylglycyl)-L-phenylalanine

19 October 2022

107

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetics of carboxypeptidase A. The pH dependence of tripeptide hydrolysis catalyzed by zinc, cobalt, and manganese enzymes

19 October 2022

109

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetics of carboxypeptidase A. pH and temperature dependence of tripeptide hydrolysis

19 October 2022

110

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The pH dependence of the nitrotyrosine-248 and arsanilazotyrosine-248 carboxypeptidase A catalyzed hydrolysis of O-(trans-p-chlorocinnamoyl)-L-.beta.-phenyllactate

19 October 2022

111

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

pH Dependence and competitive product inhibition of the carboxypeptidase A catalyzed hydrolysis of O-(trans-cinnamoyl) L-.beta.-phenyllactate

19 October 2022

112

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

pH Dependence of the Hydrolysis of O-Acetyl-L-mandelate Catalyzed by Carboxypeptidase A. A Critical Examination1,2

19 October 2022

113

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

The effect of raney nickel on the covalent thymidylate synthetase-5-fluoro-2'-deoxyuridylate-5,10-methylenetetrahydrofolate complex

19 October 2022

116

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Essential carboxyl groups in yeast hexokinase

19 October 2022

117

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Structure-function relationships in lactate dehydrogenase

19 October 2022

118

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Nuclear magnetic resonance studies of substrate interaction with cobalt substituted alcohol dehydrogenase from liver

19 October 2022

120

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Role of arginyl residues in directing carboxymethylation of horse liver alcohol dehydrogenase

19 October 2022

121

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Role of zinc in horse liver alcohol dehydrogenase. Influence on structure and conformational changes

19 October 2022

122

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Crystal and molecular structure of the salt (1-methylnicotinamide)(+) aden-9-ylacetate(-) dihydrate. A model for the intramolecular interactions of oxidized nicotinamide adenine dinucleotide

19 October 2022

125

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Structure of analogs of nicotinamide-adenine dinucleotide. I. Crystal structure of N-(3-(aden-9-yl)propyl)-3-carbamoylpyridinium bromide trihydrate, (Ade-C3-Nic+)Br-3H2O

19 October 2022

126

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Structures of analogs of nicotinamide-adenine dinucleotide. II. Crystal structure of N-(3-(Aden-9-yl) propyl)-3-carbamoylpyridinium bromide hydrobromide dihydrate, (AdeH plus-C3-Nic+)2Br-2H2O

19 October 2022

127

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Structures of analogs of nicotinamide-adenine dinucleotide. 3. Crystal structure of 1,1'-trimethylenebisnicotinamide dichloride monohydrate, (Nic plus-C3-Nic+)2CL-H2O.

19 October 2022

128

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Proton magnetic resonance study of the intramolecular association and conformation of the alpha and beta pyridine mononucleotides and nucleosides

19 October 2022

130

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Kinetic analysis of the individual reductive steps catalyzed by β-hydroxy-β-methylglutaryl-coenzyme A reductase obtained from yeast

19 October 2022

131

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

SOME STEREOSPECIFICITY STUDIES WITH TRITIATED PYRIDINE NUCLEOTIDES

19 October 2022

133

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Magnetic resonance studies of the proximity and spatial arrangement of propionyl coenzyme A and pyruvate on a biotin-metalloenzyme, transcarboxylase

19 October 2022

139

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

Stereochemistry of propionyl-coenzyme A and pyruvate carboxylations catalyzed by transcarboxylase

19 October 2022

140

1 reference

https://api.crossref.org/works/10.1002/9780470122907.CH4

19 October 2022

Identifiers

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21524

19 October 2022

1 reference