(Q37876414)

24 August 2017

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title

Leprosy susceptibility: genetic variations regulate innate and adaptive immunity, and disease outcome (English)

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24 August 2017

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Milton Ozório Moraes

4

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author name string

Cynthia Chester Cardoso

series ordinal

1

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24 August 2017

Ana Carla Pereira

series ordinal

2

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24 August 2017

Carolinne de Sales Marques

series ordinal

3

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24 August 2017

publication date

1 May 2011

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24 August 2017

number of pages

17

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based on heuristic

inferred from page(s)

published in

Future Microbiology

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24 August 2017

volume

6

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24 August 2017

issue

5

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24 August 2017

page(s)

533-549

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24 August 2017

cites work

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21 January 2018

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21 January 2018

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The continuing challenges of leprosy

21 January 2018

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Leprosy as a genetic disease

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Genetic epidemiology of the susceptibility to leprosy

21 January 2018

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A major gene controls leprosy susceptibility in a hyperendemic isolated population from north of Brazil

21 January 2018

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The natural resistance-associated macrophage protein and susceptibility to intracellular pathogens

21 January 2018

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High-resolution linkage map in the vicinity of the host resistance locus Bcg.

21 January 2018

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Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg

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Enumeration of Mycobacterium leprae using real-time PCR

21 January 2018

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Host resistance to malaria: using mouse models to explore the host response

21 January 2018

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Tumor necrosis factor promoter polymorphism and susceptibility to lepromatous leprosy

21 January 2018

1 reference

Missense mutations of the interleukin-12 receptor beta 1(IL12RB1) and interferon-gamma receptor 1 (IFNGR1) genes are not associated with susceptibility to lepromatous leprosy in Korea

21 January 2018

1 reference

Susceptibility to leprosy is associated with PARK2 and PACRG.

21 January 2018

1 reference

IFNG +874T/A, IL10 -1082G/A and TNF -308G/A polymorphisms in association with tuberculosis susceptibility: a meta-analysis study

21 January 2018

1 reference

Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for -819C/T in leprosy susceptibility.

21 January 2018

1 reference

Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction

21 January 2018

1 reference

Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states

21 January 2018

1 reference

Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes

21 January 2018

1 reference

The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm

21 January 2018

1 reference

Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy

21 January 2018

1 reference

Evidence for a cluster of genes on chromosome 17q11-q21 controlling susceptibility to tuberculosis and leprosy in Brazilians

21 January 2018

1 reference

Mycobacterium leprae downregulates the expression of PHEX in Schwann cells and osteoblasts.

21 January 2018

1 reference

A common human TLR1 polymorphism regulates the innate immune response to lipopeptides

21 January 2018

1 reference

Leprosy and the adaptation of human toll-like receptor 1.

21 January 2018

1 reference

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

Toll-like receptors control autophagy.

21 January 2018

1 reference

Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling

21 January 2018

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Genomewide association study of leprosy

21 January 2018

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Leprosy as a genetic model for susceptibility to common infectious diseases

21 January 2018

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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

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Autophagy gene variant IRGM -261T contributes to protection from tuberculosis caused by Mycobacterium tuberculosis but not by M. africanum strains

21 January 2018

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NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

21 January 2018

1 reference

Nod1 and Nod2 in innate immunity and human inflammatory disorders

21 January 2018

1 reference

Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population

21 January 2018

1 reference

C-type lectins and phagocytosis

21 January 2018

1 reference

Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility

21 January 2018

1 reference

DC-SIGN (CD209) Promoter -336 A/G polymorphism is associated with dengue hemorrhagic fever and correlated to DC-SIGN expression and immune augmentation

21 January 2018

1 reference

A variant in the CD209 promoter is associated with severity of dengue disease

21 January 2018

1 reference

Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes

21 January 2018

1 reference

SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis

21 January 2018

1 reference

TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

21 January 2018

1 reference

Low serum levels of cathelicidin LL-37 in leprosy

21 January 2018

1 reference

IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway

21 January 2018

1 reference

Divergence of macrophage phagocytic and antimicrobial programs in leprosy

21 January 2018

1 reference

Vitamin D receptor gene polymorphisms in relation to Vitamin D related disease states

21 January 2018

1 reference

Association between the TaqI polymorphism of the vitamin D receptor gene and lepromatous leprosy in a Mexican population sample

21 January 2018

1 reference

Interaction of TaqI polymorphism at exon 9 of the vitamin D receptor gene with the negative lepromin response may favor the occurrence of leprosy

21 January 2018

1 reference

SNP 668C (-44) alters a NF-kappaB1 putative binding site in non-coding strand of human beta-defensin 1 (DEFB1) and is associated with lepromatous leprosy

21 January 2018

1 reference

Association study of major risk single nucleotide polymorphisms in the common regulatory region of PARK2 and PACRG genes with leprosy in an Indian population

21 January 2018

1 reference

Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release

21 January 2018

1 reference

Parkin mono-ubiquitinates Bcl-2 and regulates autophagy

21 January 2018

1 reference

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

21 January 2018

1 reference

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

1 reference

21 January 2018

Autophagy in infection

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Ancient ubiquitous protein 1 (AUP1) localizes to lipid droplets and binds the E2 ubiquitin conjugase G2 (Ube2g2) via its G2 binding region

21 January 2018

1 reference

The lta4h locus modulates susceptibility to mycobacterial infection in zebrafish and humans

21 January 2018

1 reference

Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death

21 January 2018

1 reference

Host-derived oxidized phospholipids and HDL regulate innate immunity in human leprosy

21 January 2018

1 reference

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

21 January 2018

1 reference

Lipid droplet formation in leprosy: Toll-like receptor-regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis

21 January 2018

1 reference

Modulation of lipid droplets by Mycobacterium leprae in Schwann cells: a putative mechanism for host lipid acquisition and bacterial survival in phagosomes.

21 January 2018

1 reference

Expression of adipose differentiation-related protein (ADRP) and perilipin in macrophages infected with Mycobacterium leprae

21 January 2018

1 reference

Autophagy regulates lipid metabolism

21 January 2018

1 reference

Comparative pathogenesis of Mycobacterium marinum and Mycobacterium tuberculosis

21 January 2018

1 reference

Lymphotoxin-alpha and TNF have essential but independent roles in the evolution of the granulomatous response in experimental leprosy

21 January 2018

1 reference

Influence of TNF and IL10 gene polymorphisms in the immunopathogenesis of leprosy in the south of Brazil.

21 January 2018

1 reference

Allele-specific repression of lymphotoxin-alpha by activated B cell factor-1

21 January 2018

1 reference

Genetic deficiencies of innate immune signalling in human infectious disease

21 January 2018

1 reference

The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases

21 January 2018

1 reference

In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene.

21 January 2018

1 reference

The 3'UTR 1188 A/C polymorphism in the interleukin-12p40 gene (IL-12B) is associated with lepromatous leprosy in the west of Mexico.

21 January 2018

1 reference

Polymorphism of the 5' flanking region of the IL-12 receptor beta2 gene partially determines the clinical types of leprosy through impaired transcriptional activity

21 January 2018

1 reference

Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project

21 January 2018

1 reference

Major Transplantation Antigens in Host Responses to Infection

21 January 2018

1 reference

HLA and infectious diseases

21 January 2018

1 reference

HLA and leprosy in Koreans

21 January 2018

1 reference

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

21 January 2018

1 reference

HLA-DRB1*04 and DRB1*10 are associated with resistance and susceptibility, respectively, in Brazilian and Vietnamese leprosy patients

21 January 2018

1 reference

Immunogenetics of mycobacterial infections in the North Indian population

21 January 2018

1 reference

Molecular mechanisms of MHC linked susceptibility in leprosy: towards the development of synthetic vaccines

21 January 2018

1 reference

Arginine at positions 13 or 70-71 in pocket 4 of HLA-DRB1 alleles is associated with susceptibility to tuberculoid leprosy

21 January 2018

1 reference

Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.

21 January 2018

1 reference

Defining protective responses to pathogens: cytokine profiles in leprosy lesions

21 January 2018

1 reference

Cytokine patterns at the site of mycobacterial infection

21 January 2018

1 reference

Immunological cytokine correlates of protective immunity and pathogenesis in leprosy

21 January 2018

1 reference

Interleukin-10 promoter single-nucleotide polymorphisms as markers for disease susceptibility and disease severity in leprosy

21 January 2018

1 reference

IL-10 promoter single nucleotide polymorphisms are significantly associated with resistance to leprosy.

21 January 2018

1 reference

Massive gene decay in the leprosy bacillus

21 January 2018

1 reference

Implications of high level pseudogene transcription in Mycobacterium leprae

21 January 2018

1 reference

Adjusting to a new home: Mycobacterium tuberculosis gene expression in response to an intracellular lifestyle

21 January 2018

1 reference

Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli

21 January 2018

1 reference

TB: screening for responses to a vile visitor

21 January 2018

1 reference

Penitentiary or penthouse condo: the tuberculous granuloma from the microbe's point of view

21 January 2018

1 reference

Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions

21 January 2018

1 reference

Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage

21 January 2018

1 reference

Human genetics of infectious diseases: a unified theory

21 January 2018

1 reference

Seropositivity to anti-phenolic glycolipid-I in leprosy cases, contacts and no known contacts of leprosy in an endemic and a non-endemic area in northeast Brazil

21 January 2018

1 reference

Stepwise replication identifies a low-producing lymphotoxin-α allele as a major risk factor for early-onset leprosy

21 January 2018

1 reference

Segregation of HLA/TNF region is linked to leprosy clinical spectrum in families displaying mixed leprosy subtypes

21 January 2018

1 reference

A major susceptibility locus for leprosy in India maps to chromosome 10p13

21 January 2018

1 reference

Comparative genomic and phylogeographic analysis of Mycobacterium leprae

21 January 2018

1 reference

IFNG +874 T>A single nucleotide polymorphism is associated with leprosy among Brazilians

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FMB.11.39

1 reference

24 August 2017

1 reference