(Q37878247)

24 August 2017

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title

Discovering imaging endophenotypes for major depression (English)

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24 August 2017

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G Hasler

1

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author name string

G Northoff

series ordinal

2

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PubMed ID

21602829

24 August 2017

language of work or name

English

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publication date

1 June 2011

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24 August 2017

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24 August 2017

16

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24 August 2017

6

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24 August 2017

604-619

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https://scigraph.springernature.com/pub.10.1038/mp.2011.23

24 August 2017

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Gender differences in the rates of exposure to stressful life events and sensitivity to their depressogenic effects

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Exposure to novelty and forced swimming evoke stressor-dependent changes in extracellular GABA in the rat hippocampus.

21 January 2018

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Area-dependent changes in GABAergic function after acute and chronic cold stress.

21 January 2018

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Extracellular levels of serotonin and GABA in the hippocampus after chronic mild stress in rats. A microdialysis study in an animal model of depression.

21 January 2018

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Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography

21 January 2018

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GABAA receptors mediate the changes produced by stress on GABA function and locomotor activity.

21 January 2018

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Chronic stress regulates levels of mRNA transcripts encoding beta subunits of the GABA(A) receptor in the rat stress axis.

21 January 2018

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Differential effects of olfactory bulbectomy on GABAA and GABAB receptors in the rat brain.

21 January 2018

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Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy.

21 January 2018

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The complex roles of neurosteroids in depression and anxiety disorders.

21 January 2018

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Comparison of plasma input and reference tissue models for analysing [(11)C]flumazenil studies

21 January 2018

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Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder

21 January 2018

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Getting excited about GABA and sex differences in the brain

21 January 2018

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Sex differences in GABA/benzodiazepine receptor changes and corticosterone release after acute stress in rats.

21 January 2018

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Sex-differences and stress: effects on regional high and low affinity [3H]GABA binding

21 January 2018

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13C magnetic resonance spectroscopy studies of alterations in glutamate neurotransmission

21 January 2018

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Alcohol, allopregnanolone and aggression in mice

21 January 2018

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Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region.

21 January 2018

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Altered Organization of GABA(A) Receptor mRNA Expression in the Depressed Suicide Brain

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21 January 2018

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Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia

21 January 2018

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21 January 2018

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Increased brain GABA concentrations following acute administration of a selective serotonin reuptake inhibitor

21 January 2018

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21 January 2018

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Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase

21 January 2018

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Association between glutamic acid decarboxylase genes and anxiety disorders, major depression, and neuroticism

21 January 2018

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Reduced level of glutamic acid decarboxylase-67 kDa in the prefrontal cortex in major depression.

21 January 2018

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Reduced density of calbindin immunoreactive GABAergic neurons in the occipital cortex in major depression: relevance to neuroimaging studies

21 January 2018

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GABAergic neurons immunoreactive for calcium binding proteins are reduced in the prefrontal cortex in major depression

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Stress and GABA receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Serotonin transporter and GABAA alpha 6 receptor variants are associated with neuroticism

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Evidence of association between gamma-aminobutyric acid type A receptor genes located on 5q34 and female patients with mood disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Possible association between a haplotype of the GABA-A receptor alpha 1 subunit gene (GABRA1) and mood disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

The gamma amino butyric acid (GABA) receptor alpha-3 subunit gene polymorphism in unipolar depressive disorder: a genetic association study

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Serotonin as a modulator of glutamate- and GABA-mediated neurotransmission: implications in physiological functions and in pathology

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Differential regional and cellular distribution of dopamine D2-like receptors: an immunocytochemical study of subtype-specific antibodies in rat and human brain

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Metabolic changes within the left dorsolateral prefrontal cortex occurring with electroconvulsive therapy in patients with treatment resistant unipolar depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Proton MR spectroscopy of the hippocampus at 3 T in patients with unipolar major depressive disorder: correlates and predictors of treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

The relationship between aberrant neuronal activation in the pregenual anterior cingulate, altered glutamatergic metabolism, and anhedonia in major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Hippocampal metabolic abnormalities at first onset and with recurrent episodes of a major depressive disorder: a proton magnetic resonance spectroscopy study

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Emerging role of glutamate in the pathophysiology of major depressive disorder.

21 January 2018

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The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Magnetic resonance spectroscopy studies of glutamate-related abnormalities in mood disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Neurotrophic effects of electroconvulsive therapy: a proton magnetic resonance study of the left amygdalar region in patients with treatment-resistant depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Stress activation of glutamate neurotransmission in the prefrontal cortex: implications for dopamine-associated psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Temporal dynamics of glutamate efflux in the prefrontal cortex and in the hippocampus following repeated stress: effects of pretreatment with saline or diazepam.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Corticotropin-releasing hormone, glutamate, and γ-aminobutyric acid in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Gating of information flow within the limbic system and the pathophysiology of schizophrenia

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Anatomical substrates for glutamate-dopamine interactions: evidence for specificity of connections and extrasynaptic actions

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Gliogenesis and glial pathology in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Altered prefrontal glutamate-glutamine-gamma-aminobutyric acid levels and relation to low cognitive performance and depressive symptoms in type 1 diabetes mellitus.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Striatal excitatory amino acid transporter transcript expression in schizophrenia, bipolar disorder, and major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression

21 January 2018

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AMPA receptor subunit 1 (GluR-A) knockout mice model the glutamate hypothesis of depression.

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Abnormal glutamate receptor expression in the medial temporal lobe in schizophrenia and mood disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Reduced levels of NR2A and NR2B subunits of NMDA receptor and PSD-95 in the prefrontal cortex in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

A default mode of brain function

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Neurobiology of emotion perception II: Implications for major psychiatric disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Positron emission tomography imaging in depression: a neural systems perspective

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Modulating limbic-cortical circuits in depression: targets of antidepressant treatments

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Targeted electrode-based modulation of neural circuits for depression

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

Imaging phenotypes of major depressive disorder: genetic correlates

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.23

A meta-analytic study of changes in brain activation in depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Neurocircuitry of mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Altered negative BOLD responses in the default-mode network during emotion processing in depressed subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Neural response to catecholamine depletion in unmedicated subjects with major depressive disorder in remission and healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Psychopathology and pathophysiology of the self in depression - neuropsychiatric hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

In search of the depressive self: extended medial prefrontal network during self-referential processing in major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Increased self-focus in major depressive disorder is related to neural abnormalities in subcortical-cortical midline structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Self-referential processing in our brain--a meta-analysis of imaging studies on the self

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Is our self nothing but reward? Neuronal overlap and distinction between reward and personal relevance and its relation to human personality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Resting GABA concentration predicts peak gamma frequency and fMRI amplitude in response to visual stimulation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Rest-stimulus interaction in the brain: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Evidence of cortical inhibitory deficits in major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Deep brain stimulation for OCD and major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

A review of systems and networks of the limbic forebrain/limbic midbrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Neural connectivity as an intermediate phenotype: brain networks under genetic control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Intermediate phenotypes and genetic mechanisms of psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Neural mechanisms of a genome-wide supported psychosis variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Resting state corticolimbic connectivity abnormalities in unmedicated bipolar disorder and unipolar depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Resting state default-mode network connectivity in early depression using a seed region-of-interest analysis: decreased connectivity with caudate nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Limbic-frontal circuitry in major depression: a path modeling metanalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Exploratory structural equation modeling of resting-state fMRI: applicability of group models to individual subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Increased neural resources recruitment in the intrinsic organization in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Anatomical Connectivity of the Subgenual Cingulate Region Targeted with Deep Brain Stimulation for Treatment-Resistant Depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Resting-state functional connectivity reflects structural connectivity in the default mode network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Genetic control over the resting brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Decreased regional homogeneity in insula and cerebellum: a resting-state fMRI study in patients with major depression and subjects at high risk for major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Orbitofrontal cortical dysfunction in akinetic catatonia: a functional magnetic resonance imaging study during negative emotional stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Functional connectivity bias of the orbitofrontal cortex in drug-free patients with major depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Neural substrates of increased memory sensitivity for negative stimuli in major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Self-referential processing of negative stimuli within the ventral anterior cingulate gyrus and right amygdala

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Fronto-cingulate effective connectivity in major depression: a study with fMRI and dynamic causal modeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Aberrant functional connectivity of dorsolateral prefrontal and cingulate networks in patients with major depression during working memory processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

5-HTT genotype effect on prefrontal-amygdala coupling differs between major depression and controls.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

The neuropsychology of mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Clock Mutants of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Searching for genes underlying behavior: lessons from circadian rhythms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

Desipramine does not alter plasma GABA in patients with major depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Stability of plasma GABA at four-year follow-up in patients with primary unipolar depression

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Sex differences in GABA turnover and glutamic acid decarboxylase (GAD(65) and GAD(67)) mRNA in the rat hypothalamus

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Tiagabine for rage, aggression, and anxiety

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Positive and negative motivation in nucleus accumbens shell: bivalent rostrocaudal gradients for GABA-elicited eating, taste "liking"/"disliking" reactions, place preference/avoidance, and fear.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Plasma GABA in affective illness. A preliminary investigation

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Genetic modulation of GABA levels in the anterior cingulate cortex by GAD1 and COMT

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Positive association between the GABRA5 gene and unipolar recurrent major depression

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Hippocampal interneurons are excited via serotonin-gated ion channels.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Inhibitory control of the GABAergic transmission in the rat neostriatum by D2 dopamine receptors

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Bidirectional dopamine modulation of GABAergic inhibition in prefrontal cortical pyramidal neurons.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Negative affectivity, self-referential processing and the cortical midline structures

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Therapeutic brain stimulation and cortical excitability in depressed patients

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Investigating neural primacy in Major Depressive Disorder: multivariate Granger causality analysis of resting-state fMRI time-series data

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.23

7 January 2021

Identifiers

DOI

10.1038/MP.2011.23

1 reference

24 August 2017

1 reference

PubMed ID

21602829