(Q37880077)

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Chronic obstructive pulmonary disease: patho-physiology, current methods of treatment and the potential for simvastatin in disease management

scientific article published on 26 May 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 August 2017

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Europe PubMed Central

Chronic obstructive pulmonary disease: patho-physiology, current methods of treatment and the potential for simvastatin in disease management (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

chronic obstructive pulmonary disease

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based on heuristic

inferred from title

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1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

5

object named as

Daniela Traini

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Europe PubMed Central

PubMed publication ID

24 August 2017

author name string

Laura Marin

1

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

Paolo Colombo

2

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Europe PubMed Central

PubMed publication ID

24 August 2017

Paul M Young

4

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Europe PubMed Central

PubMed publication ID

24 August 2017

language of work or name

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publication date

26 May 2011

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Europe PubMed Central

PubMed publication ID

24 August 2017

Expert Opinion on Drug Delivery

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Europe PubMed Central

PubMed publication ID

24 August 2017

8

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Europe PubMed Central

PubMed publication ID

24 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

1205-1220

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Chronic bronchitis before age 50 years predicts incident airflow limitation and mortality risk

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Treatment of chronic obstructive pulmonary disease and its comorbidities.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statin use is associated with reduced mortality in COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statin use reduces decline in lung function: VA Normative Aging Study

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Alveolar macrophages as orchestrators of COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Endotoxin tolerance: new mechanisms, molecules and clinical significance

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Role of nuclear factor-kappaB in the immune system and bone

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Two tumour necrosis factor receptors: structure and function.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

JNK or IKK, AP-1 or NF-kappaB, which are the targets for MEK kinase 1 action?

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Alveolar macrophage replication. One mechanism for the expansion of the mononuclear phagocyte population in the chronically inflamed lung

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

The macrophage in chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Matrix metalloproteinase-9 promoter polymorphism associated with upper lung dominant emphysema

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Development of cell adhesion molecule antagonists as therapeutics for asthma and COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Structural basis for selectin mechanochemistry

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Inhalation therapy: technological milestones in asthma treatment

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

The TORCH (towards a revolution in COPD health) survival study protocol

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT trial

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Future treatments for chronic obstructive pulmonary disease and its comorbidities

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pharmacological actions of statins: potential utility in COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Exercise capacity and cytochrome oxidase activity in muscle mitochondria of COPD patients

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Cardiovascular mortality and morbidity in chronic obstructive pulmonary disease: the impact of bronchodilator treatment

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Tiotropium for stable chronic obstructive pulmonary disease: A meta-analysis

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

The effects of fluticasone with or without salmeterol on systemic biomarkers of inflammation in chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Potential benefits of statins on morbidity and mortality in chronic obstructive pulmonary disease: a review of the evidence

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Bacteria, antibiotics and COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Delivery of antibiotics to the respiratory tract: an update

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Cospray dried antibiotics for dry powder lung delivery

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

PDE4 inhibitors in COPD--a more selective approach to treatment

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Role of HDAC2 in the pathophysiology of COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Angiotensin II and inflammation: the effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Treating systemic effects of COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Potential therapeutic role for statins in respiratory disease

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Squalene synthase: a critical enzyme in the cholesterol biosynthesis pathway

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pleiotropic effects of statins

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Simvastatin attenuates experimental small airway remodelling in rats

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statins inhibit matrix metalloproteinase release from human lung fibroblasts

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statins: mechanism of action and effects.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Rho GTPases and the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

The influence of SLCO1B1 (OATP1B1) gene polymorphisms on response to statin therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Magnesium cation effect on passive diffusion of statin molecules: molecular chromatography approach

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pharmacokinetics of the CYP 3A substrate simvastatin following administration of delayed versus immediate release oral dosage forms

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Human carboxylesterase isozymes: catalytic properties and rational drug design

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Cytochrome P-450 3A4: regulation and role in drug metabolism

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

The human hepatic metabolism of simvastatin hydroxy acid is mediated primarily by CYP3A, and not CYP2D6.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pharmacology of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins), including rosuvastatin and pitavastatin

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statin safety: an overview and assessment of the data--2005.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statins and hepatotoxicity: focus on patients with fatty liver

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Statin safety: lessons from new drug applications for marketed statins.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

New insights into mechanisms of statin-associated myotoxicity

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Rhabdomyolysis and HMG-CoA reductase inhibitors

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

An overview of statin-associated proteinuria

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

A controlled trial of 6-weeks' treatment with a novel inhaled phosphodiesterase type-4 inhibitor in COPD.

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Pharmacology of a potent and selective inhibitor of PDE4 for inhaled administration

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Structure and catalytic properties of carboxylesterase isozymes involved in metabolic activation of prodrugs

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Expression and localization of CYP3A4 and CYP3A5 in human lung

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.588697

21 January 2018

Identifiers

10.1517/17425247.2011.588697

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 August 2017

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