(Q37887493)

24 August 2017

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title

Epigenetics of haematopoietic cell development (English)

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24 August 2017

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Howard Cedar

1

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PubMed ID

21660052

24 August 2017

Yehudit Bergman

series ordinal

2

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24 August 2017

10 June 2011

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Nature Reviews Immunology

24 August 2017

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24 August 2017

11

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24 August 2017

478-488

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24 August 2017

7

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Epigenetic control of recombination in the immune system

24 August 2017

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Chromosomal subunits in active genes have an altered conformation

31 March 2020

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Synthesis of globin ribonucleic acid from duck-reticulocyte chromatin in vitro

31 March 2020

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Chromatin architecture and the generation of antigen receptor diversity

31 March 2020

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Eucaryotic DNA: organization of the genome for replication

31 March 2020

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31 March 2020

Replicating by the clock

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Mapping of DNAase I sensitive regions on mitotic chromosomes

31 March 2020

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Establishment of transcriptional competence in early and late S phase

31 March 2020

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Sp1 elements protect a CpG island from de novo methylation

31 March 2020

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Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

31 March 2020

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DNA methylation affects the formation of active chromatin

31 March 2020

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DNA methylation patterns and epigenetic memory

31 March 2020

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Histones: annotating chromatin

31 March 2020

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Epigenetic regulators and histone modification

31 March 2020

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A model for transmission of the H3K27me3 epigenetic mark

31 March 2020

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

31 March 2020

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Role of the polycomb protein EED in the propagation of repressive histone marks

31 March 2020

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Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2)

31 March 2020

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The DNA-encoded nucleosome organization of a eukaryotic genome

31 March 2020

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Intrinsic histone-DNA interactions are not the major determinant of nucleosome positions in vivo

31 March 2020

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Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.

31 March 2020

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

31 March 2020

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A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

31 March 2020

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Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin

31 March 2020

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Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells

31 March 2020

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

31 March 2020

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

31 March 2020

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Direct reprogramming of human neural stem cells by OCT4.

31 March 2020

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Establishment of a normal hematopoietic and leukemia stem cell hierarchy.

31 March 2020

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The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

31 March 2020

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Flk-2 is a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells

31 March 2020

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Reductive isolation from bone marrow and blood implicates common lymphoid progenitors as the major source of thymopoiesis

31 March 2020

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Flk2+ common lymphoid progenitors possess equivalent differentiation potential for the B and T lineages

31 March 2020

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Identification of clonogenic common lymphoid progenitors in mouse bone marrow.

31 March 2020

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

31 March 2020

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Hematopoiesis: an evolving paradigm for stem cell biology

31 March 2020

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Delineating the cellular pathways of hematopoietic lineage commitment

31 March 2020

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Load and lock: the molecular mechanisms of B-lymphocyte commitment.

31 March 2020

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Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

31 March 2020

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Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

31 March 2020

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Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

31 March 2020

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

31 March 2020

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Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

31 March 2020

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Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages

31 March 2020

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Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system

31 March 2020

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Transcription control of early B cell differentiation

31 March 2020

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Densely interconnected transcriptional circuits control cell states in human hematopoiesis

31 March 2020

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Comprehensive methylome map of lineage commitment from haematopoietic progenitors

31 March 2020

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Targets and dynamics of promoter DNA methylation during early mouse development.

31 March 2020

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A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

31 March 2020

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

31 March 2020

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

31 March 2020

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Acquired mutations in TET2 are common in myelodysplastic syndromes

31 March 2020

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Mutation in TET2 in myeloid cancers

31 March 2020

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A common genetic mechanism in malignant bone marrow diseases.

31 March 2020

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Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

31 March 2020

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DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

31 March 2020

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The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis.

31 March 2020

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The Polycomb group protein EZH2 directly controls DNA methylation

31 March 2020

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DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

31 March 2020

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DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells

31 March 2020

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Induction of Tumors in Mice by Genomic Hypomethylation

31 March 2020

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De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells

31 March 2020

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Polycomb complexes and epigenetic states

31 March 2020

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Stem cell regulation by polycomb repressors: postponing commitment

31 March 2020

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Polycomb response elements and targeting of Polycomb group proteins in Drosophila.

31 March 2020

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A vertebrate Polycomb response element governs segmentation of the posterior hindbrain

31 March 2020

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A region of the human HOXD cluster that confers polycomb-group responsiveness

31 March 2020

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Inactive yet indispensable: the tale of Jarid2.

31 March 2020

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Genome-wide identification of polycomb-associated RNAs by RIP-seq

31 March 2020

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Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.

31 March 2020

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

31 March 2020

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Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells

31 March 2020

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Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

31 March 2020

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

31 March 2020

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High-resolution profiling of histone methylations in the human genome

31 March 2020

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Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation

31 March 2020

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Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells.

31 March 2020

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Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors

31 March 2020

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Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

31 March 2020

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Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.

31 March 2020

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Epigenetic characterization of hematopoietic stem cell differentiation using miniChIP and bisulfite sequencing analysis

31 March 2020

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Differential H3K4 methylation identifies developmentally poised hematopoietic genes

31 March 2020

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Lymphoid-affiliated genes are associated with active histone modifications in human hematopoietic stem cells

31 March 2020

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A unique H3K4me2 profile marks tissue-specific gene regulation

31 March 2020

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From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment

31 March 2020

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Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells

31 March 2020

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Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.

31 March 2020

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Stem cell-specific epigenetic priming and B cell-specific transcriptional activation at the mouse Cd19 locus

31 March 2020

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Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells

31 March 2020

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Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells

31 March 2020

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Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase

31 March 2020

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Chromatin remodeling at the Ig loci prior to V(D)J recombination

31 March 2020

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Stepwise activation of the immunoglobulin mu heavy chain gene locus

31 March 2020

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Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments

31 March 2020

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Activation of V(D)J recombination at the IgH chain JH locus occurs within a 6-kilobase chromatin domain and is associated with nucleosomal remodeling

31 March 2020

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Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4

31 March 2020

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Repeat organization and epigenetic regulation of the DH-Cmu domain of the immunoglobulin heavy-chain gene locus

31 March 2020

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Epigenetic ontogeny of the Igk locus during B cell development

31 March 2020

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The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling

31 March 2020

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Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.

31 March 2020

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A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement

31 March 2020

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

31 March 2020

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H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations

31 March 2020

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The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci.

31 March 2020

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Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development

31 March 2020

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Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites

31 March 2020

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CTCF: master weaver of the genome

31 March 2020

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The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions.

31 March 2020

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Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

31 March 2020

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Yin Yang 1 is a critical regulator of B-cell development

31 March 2020

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Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.

31 March 2020

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The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells

31 March 2020

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C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5'-nontranslatable exon

31 March 2020

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Immunoglobulin heavy chain germ-line JH-C mu transcription in human precursor B lymphocytes initiates in a unique region upstream of DQ52.

31 March 2020

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Impaired immunoglobulin gene rearrangement in mice lacking the IL-7 receptor

31 March 2020

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Initiation and processing of two kappa immunoglobulin germ line transcripts in mouse B cells

31 March 2020

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Biallelic germline transcription at the kappa immunoglobulin locus

31 March 2020

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Antisense intergenic transcription in V(D)J recombination.

31 March 2020

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Cutting edge: SWI/SNF mediates antisense Igh transcription and locus-wide accessibility in B cell precursors

31 March 2020

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The mouse immunoglobulin heavy chain V-D intergenic sequence contains insulators that may regulate ordered V(D)J recombination

31 March 2020

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Kappa chain monoallelic demethylation and the establishment of allelic exclusion

31 March 2020

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Differential accessibility at the kappa chain locus plays a role in allelic exclusion

31 March 2020

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Cytidine deaminases: AIDing DNA demethylation?

31 March 2020

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5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

31 March 2020

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Chance, necessity and antibody gene dynamics

31 March 2020

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Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

31 March 2020

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RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

31 March 2020

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Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

31 March 2020

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A recombination silencer that specifies heterochromatin positioning and ikaros association in the immunoglobulin kappa locus

31 March 2020

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Asynchronous replication and allelic exclusion in the immune system

31 March 2020

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Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments

31 March 2020

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Monoallelic expression of multiple genes in the CNS.

31 March 2020

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Widespread monoallelic expression on human autosomes

31 March 2020

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Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed.

31 March 2020

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Asynchronous replication and autosome-pair non-equivalence in human embryonic stem cells

31 March 2020

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Allelic inactivation of rDNA loci

31 March 2020

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31 March 2020

SnapShot: hematopoiesis

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21660052

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Histone acetylation and X inactivation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21660052

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Active DNA demethylation: many roads lead to Rome.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21660052

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRI2991

1 reference

24 August 2017

1 reference

PubMed ID

21660052