(Q37895102)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

review article

3 references

3 November 2020

19 January 2021

Keeping an eye on myocilin: a complex molecule associated with primary open-angle glaucoma susceptibility (English)

1 reference

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6 February 2020

1 reference

3 November 2020

1 reference

3 November 2020

1 reference

19 January 2021

Farid Menaa

1

1 reference

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6 February 2020

Carolina Ayumi Braghini

2

1 reference

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6 February 2020

Jose Paulo Cabral De Vasconcellos

3

1 reference

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6 February 2020

Bouzid Menaa

4

1 reference

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6 February 2020

Vital Paulino Costa

5

1 reference

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6 February 2020

Eugênio Santana De Figueiredo

6

1 reference

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6 February 2020

Monica Barbosa De Melo

7

1 reference

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6 February 2020

language of work or name

English

0 references

publication date

27 June 2011

3 references

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6 February 2020

3 November 2020

19 January 2021

20

1 reference

inferred from page(s)

published in

Molecules

3 references

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6 February 2020

3 November 2020

19 January 2021

16

1 reference

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6 February 2020

issue

7

1 reference

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6 February 2020

page(s)

5402-5421

1 reference

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Creative Commons Attribution

6 February 2020

copyright license

2 references

3 November 2020

19 January 2021

0 references

Founder TIGR/myocilin mutations for glaucoma in the Québec population.

1 reference

12 December 2020

Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis

1 reference

12 December 2020

The management of complicated glaucoma

1 reference

12 December 2020

Molecular and clinical evaluation of a patient hemizygous for TIGR/MYOC.

1 reference

12 December 2020

Characterization and differential expression of a human gene family of olfactomedin-related proteins

1 reference

12 December 2020

Interaction of recombinant myocilin with the matricellular protein SPARC: functional implications

1 reference

12 December 2020

Association of a single nucleotide polymorphism in the TIGR/MYOCILIN gene promoter with the severity of primary open-angle glaucoma.

1 reference

12 December 2020

Myocilin mt.1 gene promoter single nucleotide polymorphism (-1000C>G) in Brazilian patients with primary open angle glaucoma

1 reference

12 December 2020

Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis

1 reference

12 December 2020

Olfactomedin domain-containing proteins: possible mechanisms of action and functions in normal development and pathology

1 reference

12 December 2020

Four structurally distinct neuron-specific olfactomedin-related glycoproteins produced by differential promoter utilization and alternative mRNA splicing from a single gene

1 reference

12 December 2020

Rescue of glaucoma-causing mutant myocilin thermal stability by chemical chaperones

1 reference

12 December 2020

Dorsalization of the neural tube by Xenopus tiarin, a novel patterning factor secreted by the flanking nonneural head ectoderm

1 reference

12 December 2020

Using CLUSTAL for multiple sequence alignments

1 reference

12 December 2020

Glaucoma: genes, phenotypes, and new directions for therapy

1 reference

12 December 2020

Interaction of myocilin with the C-terminal region of hevin

1 reference

12 December 2020

I-TASSER server for protein 3D structure prediction

1 reference

12 December 2020

1 reference

12 December 2020

A cellular assay distinguishes normal and mutant TIGR/myocilin protein

1 reference

12 December 2020

The number of people with glaucoma worldwide in 2010 and 2020

1 reference

12 December 2020

Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium

1 reference

12 December 2020

Functional analysis of the glaucoma-causing TIGR/myocilin protein: integrity of amino-terminal coiled-coil regions and olfactomedin homology domain is essential for extracellular adhesion and secretion

1 reference

12 December 2020

Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.

1 reference

12 December 2020

Localization of MYOC transcripts in human eye and optic nerve by in situ hybridization

1 reference

12 December 2020

Mutations including the promoter region of myocilin/TIGR gene

1 reference

12 December 2020

Digenic inheritance of early-onset glaucoma: CYP1B1, a potential modifier gene

1 reference

12 December 2020

Apolipoprotein E-promoter single-nucleotide polymorphisms affect the phenotype of primary open-angle glaucoma and demonstrate interaction with the myocilin gene

1 reference

12 December 2020

Primary open-angle glaucoma

1 reference

12 December 2020

The presence and properties of myocilin in the aqueous humor

1 reference

12 December 2020

Interaction between two glaucoma genes, optineurin and myocilin

1 reference

12 December 2020

Identification of a gene that causes primary open angle glaucoma.

1 reference

12 December 2020

Analysis of glucocorticoid-induced MYOC expression in human trabecular meshwork cells

1 reference

12 December 2020

Functional role of proteolytic processing of recombinant myocilin in self-aggregation

1 reference

12 December 2020

Genome-wide expression profile of human trabecular meshwork cultured cells, nonglaucomatous and primary open angle glaucoma tissue.

1 reference

12 December 2020

Association of the myocilin mt.1 promoter variant with the worsening of glaucomatous disease over time.

1 reference

12 December 2020

Biological properties of trabecular meshwork cells

1 reference

12 December 2020

Myocilin and glaucoma: facts and ideas.

1 reference

12 December 2020

Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma

1 reference

12 December 2020

Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyte

1 reference

12 December 2020

Elucidation of subfamily segregation and intramolecular coevolution of the olfactomedin-like proteins by comprehensive phylogenetic analysis and gene expression pattern assessment.

1 reference

12 December 2020

Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4

1 reference

12 December 2020

Interaction of myocilin with gamma-synuclein affects its secretion and aggregation

1 reference

12 December 2020

1 reference

12 December 2020

Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma

1 reference

12 December 2020

Myocilin binding to Hep II domain of fibronectin inhibits cell spreading and incorporation of paxillin into focal adhesions

1 reference

12 December 2020

Bioinformatic approaches for identification and characterization of olfactomedin related genes with a potential role in pathogenesis of ocular disorders.

1 reference

12 December 2020

Protein interactions with myocilin

1 reference

12 December 2020

I-TASSER: a unified platform for automated protein structure and function prediction

1 reference

12 December 2020

Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants

1 reference

12 December 2020

Post-transcriptional modification of the gene genetically linked to juvenile open-angle glaucoma; novel transcripts in human ocular tissues

1 reference

12 December 2020

Cloning and characterization of subtracted cDNAs from a human ciliary body library encoding TIGR, a protein involved in juvenile open angle glaucoma with homology to myosin and olfactomedin.

1 reference

12 December 2020

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function

1 reference

12 December 2020

Open-angle glaucoma -- an epidemiologic overview

1 reference

12 December 2020

Elevated amounts of myocilin in the aqueous humor of transgenic mice cause significant changes in ocular gene expression

1 reference

12 December 2020

Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma

1 reference

12 December 2020

Structural changes of the trabecular meshwork in different kinds of glaucoma

1 reference

12 December 2020

TIGR/myocilin in human aqueous humor

1 reference

12 December 2020

Characterization of the mouse Myoc/Tigr gene.

1 reference

12 December 2020

Identification and characterization of CRG-L2, a new marker for liver tumor development

1 reference

12 December 2020

Characterization and comparison of the human and mouse GLC1A glaucoma genes

1 reference

12 December 2020

Penetrance and phenotype of the Cys433Arg myocilin mutation in a family pedigree with primary open-angle glaucoma

1 reference

12 December 2020

Age-dependent prevalence of mutations at the GLC1A locus in primary open-angle glaucoma

1 reference

12 December 2020

Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

1 reference

12 December 2020

Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product

1 reference

12 December 2020

Bioencapsulation of apomyoglobin in nanoporous organosilica sol-gel glasses: influence of the siloxane network on the conformation and stability of a model protein

1 reference

12 December 2020

Optimedin: a novel olfactomedin-related protein that interacts with myocilin

1 reference

12 December 2020

Recurrent mutations in a single exon encoding the evolutionarily conserved olfactomedin-homology domain of TIGR in familial open-angle glaucoma

1 reference

12 December 2020

Distribution of Myocilin and Extracellular Matrix Components in the Corneoscleral Meshwork of Human Eyes

1 reference

12 December 2020

Molecular cloning of olfactomedin, an extracellular matrix protein specific to olfactory neuroepithelium

1 reference

12 December 2020

Olfactomedin: purification, characterization, and localization of a novel olfactory glycoprotein

1 reference

12 December 2020

Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants

1 reference

12 December 2020

Localization of myocilin/trabecular meshwork--inducible glucocorticoid response protein in the human eye

1 reference

12 December 2020

Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma

1 reference

12 December 2020

The identification of myocilin-associated proteins in the human trabecular meshwork

1 reference

12 December 2020

Evaluation of the myocilin (MYOC) glaucoma gene in monkey and human steroid-induced ocular hypertension

1 reference

12 December 2020

Aggregated myocilin induces russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma

1 reference

12 December 2020

Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor

1 reference

12 December 2020

Characterization of the intracellular proteolytic cleavage of myocilin and identification of calpain II as a myocilin-processing protease.

1 reference

12 December 2020

Genomic organization of the human myocilin gene (MYOC) responsible for primary open angle glaucoma (GLC1A).

1 reference

12 December 2020

I-TASSER: fully automated protein structure prediction in CASP8

1 reference

12 December 2020

A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping

1 reference

12 December 2020

Zebrafish olfactomedin 1 regulates retinal axon elongation in vivo and is a modulator of Wnt signaling pathway

1 reference

12 December 2020

What is the present pathogenetic concept of glaucomatous optic neuropathy?

1 reference

12 December 2020

The RCSB Protein Data Bank: redesigned web site and web services

1 reference

12 December 2020

A conserved postsynaptic transmembrane protein affecting neuromuscular signaling in Caenorhabditis elegans.

1 reference

12 December 2020

Ocular perfusion pressure and glaucoma: clinical trial and epidemiologic findings

1 reference

12 December 2020

1 reference

12 December 2020

The trabecular meshwork outflow pathways: structural and functional aspects.

1 reference

12 December 2020

Currents on target intraocular pressure and intraocular pressure fluctuations in glaucoma management

1 reference

12 December 2020

Characterization of myocilin-myocilin interactions

1 reference

12 December 2020

A synthetic chaperone corrects the trafficking defect and disease phenotype in a protein misfolding disorder

1 reference

12 December 2020

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

12 December 2020

Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells

1 reference

12 December 2020

Complex genetics of glaucoma susceptibility

1 reference

12 December 2020

Amassin, an olfactomedin protein, mediates the massive intercellular adhesion of sea urchin coelomocytes

1 reference

12 December 2020

Identification of flotillin-1 as a protein interacting with myocilin: implications for the pathogenesis of primary open-angle glaucoma

1 reference

12 December 2020

Tissue differential microarray analysis of dexamethasone induction reveals potential mechanisms of steroid glaucoma

1 reference

12 December 2020

Genetic linkage of familial open angle glaucoma to chromosome 1q21–q31

1 reference

12 December 2020

Understanding mechanisms of pressure-induced optic nerve damage

1 reference

12 December 2020

Gene structure and properties of TIGR, an olfactomedin-related glycoprotein cloned from glucocorticoid-induced trabecular meshwork cells

1 reference

12 December 2020

Quality assurance for the query and distribution systems of the RCSB Protein Data Bank

1 reference

12 December 2020

Myocilin is a modulator of Wnt signaling

1 reference

12 December 2020

Noelin-1 is a secreted glycoprotein involved in generation of the neural crest

1 reference

12 December 2020

Neuronal death in glaucoma

1 reference

12 December 2020

Mutated mouse and human myocilins have similar properties and do not block general secretory pathway.

1 reference

12 December 2020

10.3390/MOLECULES16075402

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21709622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

21709622

1 reference