(Q37895674)

24 August 2017

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title

Cyclooxygenase-2 inhibitors: a literature and patent review (2009 - 2010). (English)

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24 August 2017

Sai Kiran Sharma

2

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author name string

Baker Jawabrah Al-Hourani

series ordinal

1

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24 August 2017

Mavanur Suresh

series ordinal

3

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24 August 2017

Frank Wuest

series ordinal

4

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24 August 2017

language of work or name

English

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publication date

29 June 2011

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Expert Opinion on Therapeutic Patents

24 August 2017

published in

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24 August 2017

volume

21

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24 August 2017

issue

9

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24 August 2017

page(s)

1339-1432

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Cyclooxygenase enzymes: catalysis and inhibition

24 August 2017

cites work

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Cyclooxygenase enzymes: regulation and function

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Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?

21 January 2018

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The 2.0 A resolution crystal structure of prostaglandin H2 synthase-1: structural insights into an unusual peroxidase

21 January 2018

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The structures of prostaglandin endoperoxide H synthases-1 and -2.

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Current status of COX-2 inhibitors

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The search for new COX-2 inhibitors: a review of 2002 - 2008 patents

21 January 2018

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Cyclooxygenase inhibitory natural products: current status

21 January 2018

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Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity.

21 January 2018

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Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide

21 January 2018

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Nitrooxymethyl-substituted analogues of celecoxib: synthesis and pharmacological characterization

21 January 2018

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Nitrooxymethyl-substituted analogues of rofecoxib: synthesis and pharmacological characterization

21 January 2018

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Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.

21 January 2018

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Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.

21 January 2018

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Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies

21 January 2018

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A novel 1,5-diarylpyrazole derivative exerts its anti-inflammatory effect by inhibition of cyclooxygenase-2 activity as a prodrug

21 January 2018

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Novel nitro-oxy derivatives of celecoxib for the regulation of colon cancer cell growth

21 January 2018

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Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives

21 January 2018

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Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib

21 January 2018

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Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors

21 January 2018

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Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors.

21 January 2018

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Synthesis and biological evaluation of novel pyrazole compounds

21 January 2018

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A novel COX-2 inhibitor pyrazole derivative proven effective as an anti-inflammatory and analgesic drug.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Design, synthesis, and biological evaluation of 1,5-diaryl-1,2,4-triazole derivatives as selective cyclooxygenase-2 inhibitors

21 January 2018

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1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells

21 January 2018

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Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

3-arylidene-5-(4-isobutylphenyl)-2(3H)-furanones: a new series of anti-inflammatory and analgesic compounds having antimicrobial activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Pyrazolo[3,4-d]pyrimidine derivatives as COX-2 selective inhibitors: synthesis and molecular modelling studies.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and cyclooxygenase inhibitory activities of some N-acylhydrazone derivatives of isoxazolo[4,5-d]pyridazin-4(5H)-ones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo[1,2-a]pyridine symbiotic prototypes

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors

21 January 2018

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Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammat

21 January 2018

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Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.

21 January 2018

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Design and synthesis of new 1,3-benzthiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.

21 January 2018

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Mono-, di-, and triaryl substituted tetrahydropyrans as cyclooxygenase-2 and tumor growth inhibitors. Synthesis and biological evaluation.

21 January 2018

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The novel benzopyran class of selective cyclooxygenase-2 inhibitors-part I: the first clinical candidate.

21 January 2018

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The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: the second clinical candidate having a shorter and favorable human half-life

21 January 2018

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The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part III: The three microdose candidates

21 January 2018

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Inhibition of prostaglandin E2 production by synthetic wogonin analogs

21 January 2018

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New anti-inflammatory synthetic biflavonoid with C-C (6-6") linkage: differential effects on cyclooxygenase-2 and inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis, biological evaluation and docking studies of novel benzopyranone congeners for their expected activity as anti-inflammatory, analgesic and antipyretic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and biological evaluation of new 4-carboxyl quinoline derivatives as cyclooxygenase-2 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Design, synthesis, and biological evaluation of ketoprofen analogs as potent cyclooxygenase-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Design, synthesis and biological evaluation of new 2,3-diarylquinoline derivatives as selective cyclooxygenase-2 inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and pharmacological activities of some sesquiterpene quinones and hydroquinones

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and biological evaluation of nitrogen-containing chalcones as possible anti-inflammatory and antioxidant agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Design, synthesis and biological evaluation of new (E)- and (Z)-1,2,3-triaryl-2-propen-1-ones as selective COX-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

In vitro anti-inflammatory activity of carvacrol: Inhibitory effect on COX-2 catalyzed prostaglandin E(2) biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Cyclooxygenase-2 inhibitory and antioxidant compounds from the truffle Elaphomyces granulatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Sesquiterpenes from Ainsliaea fragrans and their inhibitory activities against cyclooxygenases-1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Anti-inflammatory, cyclooxygenase (COX)-2, COX-1 inhibitory and antioxidant effects of Dysophylla stellata Benth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Phenolic compounds with radical scavenging and cyclooxygenase-2 (COX-2) inhibitory activities from Dioscorea opposita

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Identification of a novel compound that inhibits iNOS and COX-2 expression in LPS-stimulated macrophages from Schisandra chinensis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide release studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and evaluation of a radioiodinated lumiracoxib derivative for the imaging of cyclooxygenase-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Acyclic triaryl olefins possessing a sulfohydroxamic acid pharmacophore: synthesis, nitric oxide/nitroxyl release, cyclooxygenase inhibition, and anti-inflammatory studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and anti-inflammatory activity of novel (substituted)benzylidene acetone oxime ether derivatives: molecular modeling study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

KO-202125, a sauristolactam derivate, induces apoptosis to prevent KB human oral squamous carcinoma cells through inhibition of cyclooxygenase-2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Design and synthesis of acyclic triaryl (Z)-olefins: a novel class of cyclooxygenase-2 (COX-2) inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

In-vitro evaluation of 5-lipoxygenase and cyclo-oxygenase inhibitors using bovine neutrophils and platelets and HPLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Effect of wogonin, a plant flavone from Scutellaria radix, on the suppression of cyclooxygenase-2 and the induction of inducible nitric oxide synthase in lipopolysaccharide-treated RAW 264.7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

The cyclooxygenase-2 inhibitor GW406381X [2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] is effective in animal models of neuropathic pain and central sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Design, Synthesis, and Biological Evaluation of 6-Substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: A Novel Class of Diarylheterocyclic Selective Cyclooxygenase-2 Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

The role of cyclooxygenase and lipoxygenase in cancer chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Bruguiesulfurol, a new sulfur compound from Bruguiera gymnorrhiza

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

Synthesis and evaluation of radioiodinated cyclooxygenase-2 inhibitors as potential SPECT tracers for cyclooxygenase-2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

A new class of acyclic 2-alkyl-1,1,2-triaryl (Z)-olefins as selective cyclooxygenase-2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2011.593510

A New Cyclooxygenase Inhibitor from Incarvillea arguta

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1515/ZNB-2009-0414

Identifiers

DOI

10.1517/13543776.2011.593510

1 reference

24 August 2017

1 reference