(Q37905128)

25 August 2017

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title

Alzheimer's disease genetics: lessons to improve disease modelling (English)

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25 August 2017

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2

John Hardy

1 reference

25 August 2017

Rita J Guerreiro

1

1 reference

25 August 2017

1 August 2011

1 reference

Biochemical Society Transactions

25 August 2017

1 reference

25 August 2017

39

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25 August 2017

4

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25 August 2017

910-916

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Progress in the modeling of neurodegenerative diseases in transgenic mice

25 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

APOE genotype effects on Alzheimer's disease onset and epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

A genome-wide association study for late-onset Alzheimer's disease using DNA pooling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide analysis of genetic loci associated with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The genetic architecture of Alzheimer's disease: beyond APP, PSENs and APOE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-Wide Association Studies in Alzheimer Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Sample tracking and use in published genome-wide association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Replication of CLU, CR1, and PICALM associations with alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genetic variation and neuroimaging measures in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Alzheimer's disease genetics: current knowledge and future challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Challenges in phenotype definition in the whole-genome era: multivariate models of memory and intelligence

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Finding the missing heritability of complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

After GWAS: searching for genetic risk for schizophrenia and bipolar disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Voxelwise genome-wide association study (vGWAS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The number of trait loci in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

A knowledge-based weighting framework to boost the power of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

NSAIDs: small molecules for prevention of Alzheimer's disease or precursors for future drug development?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Bin1 ablation increases susceptibility to cancer during aging, particularly lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Phylogenetic analysis of the MS4A and TMEM176 gene families

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Putative dual role of ephrin-Eph receptor interactions in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Synapse development and plasticity: roles of ephrin/Eph receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The structural era of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The amphiphysin family of proteins and their role in endocytosis at the synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The BAR domain proteins: molding membranes in fission, fusion, and phagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Distribution and expression of picalm in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Evidence for CALM in directing VAMP2 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

T-cell activation and immunologic synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

CD2AP/CMS regulates endosome morphology and traffic to the degradative pathway through its interaction with Rab4 and c-Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Role of ATP-binding cassette transporters in brain lipid transport and neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

ApoE promotes the proteolytic degradation of Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Complement activation and inhibition: a delicate balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Siglec receptors and hiding plaques in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Traumatic brain injury-induced acute gene expression changes in rat cerebral cortex identified by GeneChip analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Interleukin 1 regulates synthesis of amyloid beta-protein precursor mRNA in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Stress-induced transcription of the clusterin/apoJ gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST0390910

21 January 2018

Identifiers

DOI

10.1042/BST0390910

1 reference

25 August 2017

1 reference

PubMed ID

21787322