(Q37910303)

25 August 2017

1 reference

title

TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis? (English)

1 reference

amyotrophic lateral sclerosis

25 August 2017

main subject

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author name string

Michael J Strong

series ordinal

1

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25 August 2017

Kathryn Volkening

series ordinal

2

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25 August 2017

language of work or name

English

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publication date

6 September 2011

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25 August 2017

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25 August 2017

volume

278

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25 August 2017

issue

19

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25 August 2017

page(s)

3569-3577

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

25 August 2017

cites work

1 reference

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21 January 2018

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21 January 2018

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21 January 2018

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TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

21 January 2018

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TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

21 January 2018

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Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

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The evidence for altered RNA metabolism in amyotrophic lateral sclerosis (ALS).

21 January 2018

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Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

21 January 2018

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Identification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexes

21 January 2018

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Domain architectures and characterization of an RNA-binding protein, TLS

21 January 2018

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Eukaryotic stress granules: the ins and outs of translation

21 January 2018

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Dynein and kinesin regulate stress-granule and P-body dynamics

21 January 2018

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P bodies and the control of mRNA translation and degradation

21 January 2018

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Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

21 January 2018

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The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements

21 January 2018

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RNA-quality control by the exosome

21 January 2018

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

21 January 2018

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MicroRNA: Biogenesis, Function and Role in Cancer

21 January 2018

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TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration.

21 January 2018

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The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

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MicroRNAs: biogenesis and molecular functions.

21 January 2018

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MicroRNA function: multiple mechanisms for a tiny RNA?

21 January 2018

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MicroRNAs (miRNAs) in neurodegenerative diseases

21 January 2018

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MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

21 January 2018

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Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Building specificity with nonspecific RNA-binding proteins

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

hnRNP complexes: composition, structure, and function

21 January 2018

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TDP-43: new aspects of autoregulation mechanisms in RNA binding proteins and their connection with human disease

21 January 2018

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Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP-43 regulates its mRNA levels through a negative feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP-43 is a developmentally regulated protein essential for early embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Identification of an RNA binding specificity for the potential splicing factor TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Fused in sarcoma/translocated in liposarcoma: a multifunctional DNA/RNA binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Human 75-kDa DNA-pairing protein is identical to the pro-oncoprotein TLS/FUS and is able to promote D-loop formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TLS facilitates transport of mRNA encoding an actin-stabilizing protein to dendritic spines

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP43 depletion rescues aberrant CFTR exon 9 skipping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Nuclear factor TDP-43 binds to the polymorphic TG repeats in CFTR intron 8 and causes skipping of exon 9: a functional link with disease penetrance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP-43 overexpression enhances exon 7 inclusion during the survival of motor neuron pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Characterization of an RNA granule from developing brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Higher order arrangement of the eukaryotic nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP-43 is recruited to stress granules in conditions of oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL-/- mice: support for a role for TDP-43 in the physiological response to neuronal injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Mutant copper-zinc superoxide dismutase binds to and destabilizes human low molecular weight neurofilament mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TLS, EWS and TAF15: a model for transcriptional integration of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Implications of the prion-related Q/N domains in TDP-43 and FUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08277.X

10.1111/J.1742-4658.2011.08277.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference