(Q37912224)

25 August 2017

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title

Screening strategies for discovery of antibacterial natural products (English)

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25 August 2017

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Sheo B Singh

1

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25 August 2017

Katherine Young

series ordinal

2

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25 August 2017

Lynn Miesel

series ordinal

3

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25 August 2017

publication date

1 August 2011

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Expert Review of Anti-infective Therapy

25 August 2017

published in

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25 August 2017

volume

9

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25 August 2017

issue

8

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25 August 2017

page(s)

589-613

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Empirical antibacterial drug discovery--foundation in natural products

25 August 2017

cites work

1 reference

National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004.

21 January 2018

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Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America

21 January 2018

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The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America

21 January 2018

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Combating antimicrobial resistance: policy recommendations to save lives

21 January 2018

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Invasive methicillin-resistant Staphylococcus aureus infections in the United States

21 January 2018

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

21 January 2018

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Did DNA replication evolve twice independently?

21 January 2018

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Replisome mechanics: insights into a twin DNA polymerase machine

21 January 2018

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The DNA replication machine of a gram-positive organism.

21 January 2018

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DNA replication initiation: mechanisms and regulation in bacteria

21 January 2018

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21 January 2018

Bacterial RNA polymerase

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The regulation of bacterial transcription initiation

21 January 2018

1 reference

RNA polymerase: the vehicle of transcription

21 January 2018

1 reference

A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae

21 January 2018

1 reference

Global transposon mutagenesis and a minimal Mycoplasma genome

21 January 2018

1 reference

Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.

21 January 2018

1 reference

Essential Bacillus subtilis genes

21 January 2018

1 reference

An array of target-specific screening strains for antibacterial discovery

21 January 2018

1 reference

Staphylococcus aureus promoter-lux reporters for drug discovery

21 January 2018

1 reference

Quinolone Resistance Due to Reduced Target Enzyme Expression

21 January 2018

1 reference

Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

The discovery of cell wall active antibacterial antibiotics

21 January 2018

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Does the cell wall of bacteria remain a viable source of targets for novel antibiotics?

21 January 2018

1 reference

BACTERIAL PROTOPLASTS INDUCED BY PENICILLIN.

21 January 2018

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Targets and assays for discovering novel antibacterial agents.

21 January 2018

1 reference

An oldie but a goodie - cell wall biosynthesis as antibiotic target pathway

21 January 2018

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Antibacterial agents that inhibit lipid A biosynthesis.

21 January 2018

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Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala.

21 January 2018

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Multidrug resistance in Gram-negative bacteria.

21 January 2018

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Efflux-mediated drug resistance in Gram-positive bacteria

21 January 2018

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Discovery of FabH/FabF inhibitors from natural products

21 January 2018

1 reference

Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

21 January 2018

1 reference

Identification and characterization of new inhibitors of the Escherichia coli MurA enzyme

21 January 2018

1 reference

A novel inhibitor that suspends the induced fit mechanism of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA).

21 January 2018

1 reference

Phenyl thiazolyl urea and carbamate derivatives as new inhibitors of bacterial cell-wall biosynthesis

21 January 2018

1 reference

3,5-dioxopyrazolidines, novel inhibitors of UDP-N- acetylenolpyruvylglucosamine reductase (MurB) with activity against gram-positive bacteria

21 January 2018

1 reference

4-Alkyl and 4,4'-dialkyl 1,2-bis(4-chlorophenyl)pyrazolidine-3,5-dione derivatives as new inhibitors of bacterial cell wall biosynthesis

21 January 2018

1 reference

Pulvinones as bacterial cell wall biosynthesis inhibitors

21 January 2018

1 reference

Discovery of the first antibacterial small molecule inhibitors of MurB.

21 January 2018

1 reference

Biochemical characterization of an inhibitor of Escherichia coli UDP-N-acetylmuramyl-l-alanine ligase

21 January 2018

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Identification of an inhibitor of the MurC enzyme, which catalyzes an essential step in the peptidoglycan precursor synthesis pathway

21 January 2018

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Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase

21 January 2018

1 reference

A MurF inhibitor that disrupts cell wall biosynthesis in Escherichia coli

21 January 2018

1 reference

Fluorescence detection-based functional assay for high-throughput screening for MraY.

21 January 2018

1 reference

Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention.

21 January 2018

1 reference

Scintillation proximity assay for inhibitors of Escherichia coli MurG and, optionally, MraY.

21 January 2018

1 reference

A-102395, a new inhibitor of bacterial translocase I, produced by Amycolatopsis sp. SANK 60206.

21 January 2018

1 reference

A-94964, a novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. I. Taxonomy, isolation and biological activity

21 January 2018

1 reference

A novel assay of bacterial peptidoglycan synthesis for natural product screening

21 January 2018

1 reference

SOS chromotest, a direct assay of induction of an SOS function in Escherichia coli K-12 to measure genotoxicity

21 January 2018

1 reference

After 30 years of study, the bacterial SOS response still surprises us

21 January 2018

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The Escherichia coli K-12 SOS chromotest agar spot test for simple, rapid detection of genotoxic agents.

21 January 2018

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Mechanisms of quinolone action and microbial response

21 January 2018

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Quinolone effects in the SOS chromotest and the synthesis of biomacromolecules.

21 January 2018

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Determination of selectivity and efficacy of fatty acid synthesis inhibitors

21 January 2018

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Role of the murein precursor UDP-N-acetylmuramyl-L-Ala-gamma-D-Glu-meso-diaminopimelic acid-D-Ala-D-Ala in repression of beta-lactamase induction in cell division mutants

21 January 2018

1 reference

Microtiter plate bioassay to monitor the interference of antibiotics with the lipid II cycle essential for peptidoglycan biosynthesis

21 January 2018

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Panel of Bacillus subtilis reporter strains indicative of various modes of action

21 January 2018

1 reference

Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347.

21 January 2018

1 reference

DnaA: controlling the initiation of bacterial DNA replication and more

21 January 2018

1 reference

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

21 January 2018

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Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system

21 January 2018

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A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication

21 January 2018

1 reference

Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling

21 January 2018

1 reference

Chemical genetic identification of peptidoglycan inhibitors potentiating carbapenem activity against methicillin-resistant Staphylococcus aureus

21 January 2018

1 reference

The Pfam protein families database

21 January 2018

1 reference

Involvement of an essential gene, mviN, in murein synthesis in Escherichia coli

21 January 2018

1 reference

Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli

21 January 2018

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Streptococcus pyogenes YtgP (Spy_0390) complements Escherichia coli strains depleted of the putative peptidoglycan flippase MurJ.

21 January 2018

1 reference

Novel lipoglycopeptides as inhibitors of bacterial signal peptidase I.

21 January 2018

1 reference

Crystallographic and biophysical analysis of a bacterial signal peptidase in complex with a lipopeptide-based inhibitor

21 January 2018

1 reference

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors

21 January 2018

1 reference

A-94964, novel inhibitor of bacterial translocase I, produced by Streptomyces sp. SANK 60404. II. Physico-chemical properties and structure elucidation

21 January 2018

1 reference

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

21 January 2018

1 reference

Discovery of bacterial fatty acid synthase inhibitors from a Phoma species as antimicrobial agents using a new antisense-based strategy.

21 January 2018

1 reference

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

21 January 2018

1 reference

Pseudopyronines A and B, alpha-pyrones produced by a marine Pseudomonas sp. F92S91, and evidence for the conversion of 4-hydroxy-alpha-pyrone to 3-furanone

21 January 2018

1 reference

Conformation and absolute configuration of nocathiacin I determined by NMR spectroscopy and chiral capillary electrophoresis

21 January 2018

1 reference

Antibacterial evaluations of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa

21 January 2018

1 reference

Isolation and structure elucidation of thiazomycin- a potent thiazolyl peptide antibiotic from Amycolatopsis fastidiosa

21 January 2018

1 reference

The bacterial ribosome as a target for antibiotics

21 January 2018

1 reference

Ribosome structure and the mechanism of translation

21 January 2018

1 reference

Insights into the decoding mechanism from recent ribosome structures

21 January 2018

1 reference

The rpsD gene, encoding ribosomal protein S4, is autogenously regulated in Bacillus subtilis

21 January 2018

1 reference

Discovery of lucensimycins A and B from Streptomyces lucensis MA7349 using an antisense strategy

21 January 2018

1 reference

Isolation, structure, and antibacterial activities of lucensimycins D-G, discovered from Streptomyces lucensis MA7349 using an antisense strategy

21 January 2018

1 reference

Isolation, structure, and antibacterial activity of phaeosphenone from a Phaeosphaeria sp. discovered by antisense strategy.

21 January 2018

1 reference

Discovery and antibacterial activity of glabramycin A-C from Neosartorya glabra by an antisense strategy

21 January 2018

1 reference

Abyssomicins, inhibitors of the para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18-032.

21 January 2018

1 reference

Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway

21 January 2018

1 reference

Cyclothialidine and its congeners: a new class of DNA gyrase inhibitors

21 January 2018

1 reference

Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. Part 3: Chemical derivatization.

21 January 2018

1 reference

Antibiotics GE23077, novel inhibitors of bacterial RNA polymerase. I. Taxonomy, isolation and characterization

21 January 2018

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Mode of action of the microbial metabolite GE23077, a novel potent and selective inhibitor of bacterial RNA polymerase

21 January 2018

1 reference

Progress in targeting bacterial transcription

21 January 2018

1 reference

Lipiarmycin: An antibiotic inhibiting nucleic acid polymerases

21 January 2018

1 reference

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

21 January 2018

1 reference

Mutation in the Bacillus subtilis RNA polymerase beta' subunit confers resistance to lipiarmycin

21 January 2018

1 reference

The RNA polymerase "switch region" is a target for inhibitors

21 January 2018

1 reference

Stemphones, novel potentiators of imipenem activity against methicillin-resistant staphylococcus aureus, produced by Aspergillus sp. FKI-2136.

21 January 2018

1 reference

Cyslabdan, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. II. Biological activities

21 January 2018

1 reference

Cyslabdan, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. I. Taxonomy, fermentation, isolation and structural elucidation

21 January 2018

1 reference

Xanthoradone C, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2.

21 January 2018

1 reference

The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp.

21 January 2018

1 reference

Antisense-guided isolation and structure elucidation of pannomycin, a substituted cis-decalin from Geomyces pannorum

21 January 2018

1 reference

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

21 January 2018

1 reference

Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

21 January 2018

1 reference

Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad-Spectrum Antibiotic Activity

21 January 2018

1 reference

Discovery and antibacterial activity of lucensimycin C from Streptomyces lucensis

21 January 2018

1 reference

Discovery of okilactomycin and congeners from Streptomyces scabrisporus by antisense differential sensitivity assay targeting ribosomal protein S4

21 January 2018

1 reference

A new member of the class of antibiotics with thiotetronic acid structure isolated fromStreptomyces olivaceus Tü 3010

21 January 2018

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1002/JLAC.198819881105

Nocathiacins, new thiazolyl peptide antibiotics from Nocardia sp. I. Taxonomy, fermentation and biological activities.

9 March 2024

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.56.226

Novel alpha-pyrones produced by a marine Pseudomonas sp. F92S91: taxonomy and biological activities

12 April 2024

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.56.1033

The myxopyronins, new inhibitors of bacterial RNA synthesis from Myxococcus fulvus (Myxobacterales).

12 April 2024

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.36.1651

Tiacumicins, a novel complex of 18-membered macrolide antibiotics. I. Taxonomy, fermentation and antibacterial activity.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.40.567

Lipiarmycin, a new antibiotic from Actinoplanes. I. Description of the producer strain and fermentation studies.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.28.247

Identifiers

DOI

10.1586/ERI.11.81

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25 August 2017

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