(Q37915623)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

review article

1 reference

title

Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

main subject

inflammation

0 references

Tripterygium wilfordii

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

author name string

Kwong-Fai Wong

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Yi Yuan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

publication date

1 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

Clinical and Experimental Pharmacology and Physiology

10 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

page(s)

311-320

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer.

10 February 2020

cites work

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Explaining marginal benefits to patients, when "marginal" means additional but not necessarily small.

21 January 2018

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Male infertility in cancer patients: Review of the literature

21 January 2018

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Traditional Chinese herbal medicines for treatment of liver fibrosis and cancer: from laboratory discovery to clinical evaluation.

21 January 2018

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Triptolide and its expanding multiple pharmacological functions

21 January 2018

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Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

21 January 2018

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Immunosuppressive effects of Tripterygium wilfordii polysaccharide on LPS-stimulated human monocytes.

21 January 2018

1 reference

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Suppression of cytokine production and cell adhesion molecule expression in human monocytic cell line THP-1 by Tripterygium wilfordii polysaccharide moiety.

21 January 2018

1 reference

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Immunochemical characterization of the functional constituents of Tripterygium wilfordii contributing to its anti-inflammatory property

21 January 2018

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Celastrol inhibits production of nitric oxide and proinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells

21 January 2018

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Tripchlorolide protects neuronal cells from microglia-mediated beta-amyloid neurotoxicity through inhibiting NF-kappaB and JNK signaling

21 January 2018

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Celastrol inhibits breast cancer cell invasion via suppression of NF-ĸB-mediated matrix metalloproteinase-9 expression

21 January 2018

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Tripterine prevents endothelial barrier dysfunction by inhibiting endogenous peroxynitrite formation

21 January 2018

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Triptolide attenuates endotoxin- and staphylococcal exotoxin-induced T-cell proliferation and production of cytokines and chemokines

21 January 2018

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Role of LPS/CD14/TLR4-mediated inflammation in necrotizing enterocolitis: pathogenesis and therapeutic implications

21 January 2018

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Endotoxin-neutralizing peptides as gram-negative sepsis therapeutics

21 January 2018

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MyD88-dependent and independent pathways of Toll-Like Receptors are engaged in biological activity of Triptolide in ligand-stimulated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Triptolide suppresses CD80 and CD86 expressions and IL-12 production in THP-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Therapeutic effect of tripterine on adjuvant arthritis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol attenuates hypertension-induced inflammation and oxidative stress in vascular smooth muscle cells via induction of heme oxygenase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated from Celastrus regelii

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Beneficial effect of tripterine on systemic lupus erythematosus induced by active chromatin in BALB/c mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol inhibits pro-inflammatory cytokine secretion in Crohn's disease biopsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Molecular targets of celastrol derived from Thunder of God Vine: potential role in the treatment of inflammatory disorders and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Helicobacter pylori and gastric cancer: the causal relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis

21 January 2018

1 reference

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Phase II trial of curcumin in patients with advanced pancreatic cancer

21 January 2018

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Nuclear factor-kappa B: from clone to clinic

21 January 2018

1 reference

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Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Triptolide down-regulates bcr-abl expression and induces apoptosis in chronic myelogenous leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts

21 January 2018

1 reference

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The role of mutant p53 in human cancer

21 January 2018

1 reference

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Triptolide, an inhibitor of the human heat shock response that enhances stress-induced cell death

21 January 2018

1 reference

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Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

RNA polymerase - an important molecular target of triptolide in cancer cells

21 January 2018

1 reference

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Cell death and hepatocarcinogenesis: Dysregulation of apoptosis signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Cytokines and hematopoietic stem cell mobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Reactive oxygen species: a breath of life or death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Role of reactive oxygen species (ROS) in apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol isolated from Tripterygium regelii induces apoptosis through both caspase-dependent and -independent pathways in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Radiosensitization by celastrol is mediated by modification of antioxidant thiol molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Induction of mitochondrion-mediated apoptosis of CHO cells by tripchlorolide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

c-Myc degradation induced by DNA damage results in apoptosis of CHO cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

PG490-88, a new immunosuppressant, effectively prevents acute and chronic rejection in rat renal allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

(5R)-5-hydroxytriptolide inhibits the immune response of human peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

(5R)-5-hydroxytriptolide inhibits IFN-gamma-related signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Anti-AIDS Agents, 4. Tripterifordin, a Novel Anti-HIV Principle from Tripterygium wilfordii: Isolation and Structural Elucidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Immunosuppressive diterpenoids from Tripterygium wilfordii

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Inhibition by triptoquinone-A of LPS- and IL-1 beta-primed induction of NO synthase in rat thoracic aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

Insecticidal sesquiterpene pyridine alkaloids from Maytenus chiapensis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1440-1681.2011.05586.X

10.1111/J.1440-1681.2011.05586.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21834865%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference