(Q39890770)

15 September 2017

title

Tripchlorolide protects neuronal cells from microglia-mediated beta-amyloid neurotoxicity through inhibiting NF-kappaB and JNK signaling (English)

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15 September 2017

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Xiao-Dong Pan

1

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15 September 2017

Xiao-Chun Chen

2

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15 September 2017

Yuan-Gui Zhu

3

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15 September 2017

Li-Min Chen

4

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15 September 2017

Jing Zhang

5

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15 September 2017

Tian-Wen Huang

6

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15 September 2017

Qin-Yong Ye

7

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15 September 2017

Hua-Pin Huang

8

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15 September 2017

publication date

1 August 2009

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15 September 2017

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15 September 2017

volume

57

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15 September 2017

issue

11

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15 September 2017

page(s)

1227-1238

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Amyloid Peptide-Induced Cytokine and Chemokine Expression in THP-1 Monocytes Is Blocked by Small Inhibitory RNA Duplexes for Early Growth Response-1 Messenger RNA

15 September 2017

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Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells

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Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

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Inflammation and Alzheimer's disease

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NF-kappa B: ten years after

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Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity.

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Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

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7 January 2021

Frequency of stages of Alzheimer-related lesions in different age categories

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7 January 2021

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

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7 January 2021

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

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7 January 2021

Triptolide inhibits COX-2 expression via NF-kappa B pathway in astrocytes

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7 January 2021

Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice

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7 January 2021

Inducible nitric oxide synthase and argininosuccinate synthetase: co-induction in brain tissue of patients with Alzheimer's dementia and following stimulation with beta-amyloid 1-42 in vitro

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7 January 2021

Interleukin-1beta signals through a c-Jun N-terminal kinase-dependent inducible nitric oxide synthase and nitric oxide production pathway in Sertoli epithelial cells.

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7 January 2021

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease

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7 January 2021

Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1 beta production

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7 January 2021

Triptolide inhibits murine-inducible nitric oxide synthase expression by down-regulating lipopolysaccharide-induced activity of nuclear factor-kappa B and c-Jun NH2-terminal kinase

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7 January 2021

Balance between NF- B and JNK/AP-1 activity controls dendritic cell life and death

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7 January 2021

Neurotrophic and neuroprotective effects of tripchlorolide, an extract of Chinese herb Tripterygium wilfordii Hook F, on dopaminergic neurons

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7 January 2021

Inhibition by naloxone stereoisomers of beta-amyloid peptide (1-42)-induced superoxide production in microglia and degeneration of cortical and mesencephalic neurons

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7 January 2021

Signal transduction through NF-kappa B.

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7 January 2021

Neuroprotective role of tripchlorolide on inflammatory neurotoxicity induced by lipopolysaccharide-activated microglia

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7 January 2021

HIV-1-infected and/or immune-activated macrophage-secreted TNF-alpha affects human fetal cortical neural progenitor cell proliferation and differentiation

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7 January 2021

Neuroprotective actions of endogenous interleukin-1 receptor antagonist (IL-1ra) are mediated by glia.

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7 January 2021

System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40.

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7 January 2021

Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation

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7 January 2021

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease.

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7 January 2021

Inhibition of NF-KB does not induce c-Jun N-terminal kinase-mediated apoptosis in reperfusion injury

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7 January 2021

Involvement of c-Jun N-terminal kinase in rF1 mediated activation of murine peritoneal macrophages in vitro

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7 January 2021

Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide.

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7 January 2021

Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide.

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7 January 2021

Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.

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7 January 2021

Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

1 reference

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7 January 2021

Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20844

7 January 2021

Inhibition of inducible nitric-oxide synthase expression by (5R)-5-hydroxytriptolide in interferon-gamma- and bacterial lipopolysaccharide-stimulated macrophages

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20844

7 January 2021

Identifiers

DOI

10.1002/GLIA.20844

1 reference

15 September 2017

1 reference