(Q44968991)

English

Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide.

scientific article published in July 2004

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scholarly article

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Europe PubMed Central

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30 December 2019

Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15240796%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

microglial inhibitor

0 references

long-term potentiation

1 reference

based on heuristic

inferred from title

Michael J Rowan

2

1 reference

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30 December 2019

author name string

Qinwen Wang

1

1 reference

Europe PubMed Central

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30 December 2019

Roger Anwyl

3

1 reference

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30 December 2019

language of work or name

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publication date

1 July 2004

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30 December 2019

Journal of Neuroscience

1 reference

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30 December 2019

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30 December 2019

6049-6056

1 reference

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1 reference

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30 December 2019

p38 kinase is activated in the Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-amyloid activates the O-2 forming NADPH oxidase in microglia, monocytes, and neutrophils. A possible inflammatory mechanism of neuronal damage in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MAP kinase pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LTP promotes formation of multiple spine synapses between a single axon terminal and a dendrite.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of aggregated beta-amyloid in the rat hippocampus impairs synaptic transmission and plasticity and causes memory deficits

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease and Abeta toxicity: from top to bottom

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spines: structure, dynamics and regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular basis of CaMKII function in synaptic and behavioural memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease is a synaptic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New life in an old idea: the synaptic plasticity and memory hypothesis revisited

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paradoxical Actions of Hydrogen Peroxide on Long-Term Potentiation in Transgenic Superoxide Dismutase-1 Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An NMDAR-independent LTP mediated by group II metabotropic glutamate receptors and p42/44 MAP kinase in the dentate gyrus in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two components of long-term potentiation induced by different patterns of afferent activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mechanisms in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two forms of long-term potentiation in area CA1 activate different signal transduction cascades.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neuronal death in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthase in reactive astrocytes adjacent to beta-amyloid plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for superoxide in protein kinase C activation and induction of long-term potentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for postsynaptic induction and expression of NMDA receptor independent LTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15240796

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0233-04.2004

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15240796%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15240796%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15240796%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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