(Q53377986)

PubMed publication ID

16554485

13 May 2018

http://europepmc.org/abstract/MED/16554485

title

System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

0 references

1 reference

1 reference

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

author name string

Si Qin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

Catherine Colin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

Ina Hinners

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

Annie Gervais

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

Michel Mallat

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

1 March 2006

1 reference

PubMed publication ID

16554485

13 May 2018

http://europepmc.org/abstract/MED/16554485

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

page(s)

3345-3356

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

Specific regional transcription of apolipoprotein E in human brain neurons

11 May 2020

cites work

1 reference

12 December 2020

Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

1 reference

12 December 2020

Association of microglia with amyloid plaques in brains of APP23 transgenic mice

1 reference

12 December 2020

Glutamate release from microglia via glutamate transporter is enhanced by amyloid-beta peptide

1 reference

12 December 2020

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease

1 reference

12 December 2020

A mechanism for the neuroprotective effect of apolipoprotein E: isoform-specific modification by the lipid peroxidation product 4-hydroxynonenal

1 reference

12 December 2020

Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase

1 reference

12 December 2020

The cytotoxicity of chronic neuroinflammation upon basal forebrain cholinergic neurons of rats can be attenuated by glutamatergic antagonism or cyclooxygenase-2 inhibition

1 reference

12 December 2020

Effect of oxygen on induction of the cystine transporter by bacterial lipopolysaccharide in mouse peritoneal macrophages

1 reference

12 December 2020

ApoE protects cortical neurones against neurotoxicity induced by the non-fibrillar C-terminal domain of the amyloid-beta peptide.

1 reference

12 December 2020

Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function.

1 reference

12 December 2020

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

1 reference

12 December 2020

Regulation of microglial development: a novel role for thyroid hormone.

1 reference

12 December 2020

Apolipoprotein E receptors: linking brain development and Alzheimer's disease

1 reference

12 December 2020

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

1 reference

12 December 2020

Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

1 reference

12 December 2020

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

12 December 2020

Apolipoprotein E: far more than a lipid transport protein

1 reference

12 December 2020

Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells

1 reference

12 December 2020

Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.

1 reference

12 December 2020

Cytotoxic Effect of Brain Macrophages on Developing.

1 reference

12 December 2020

Different pathways for iNOS-mediated toxicity in vitro dependent on neuronal maturation and NMDA receptor expression

1 reference

12 December 2020

Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid-beta-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site

1 reference

12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

12 December 2020

Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain.

1 reference

12 December 2020

Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

1 reference

12 December 2020

Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease

1 reference

12 December 2020

Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

1 reference

12 December 2020

Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species.

1 reference

12 December 2020

Neuroprotection by memantine against neurodegeneration induced by beta-amyloid(1-40).

1 reference

12 December 2020

In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.

1 reference

12 December 2020

Memantine in moderate-to-severe Alzheimer's disease

1 reference

12 December 2020

Amyloid precursor protein-processing products affect mononuclear phagocyte activation: pathways for sAPP- and Abeta-mediated neurotoxicity.

1 reference

12 December 2020

Asymmetry of glutamine transporters in cultured neural cells

1 reference

12 December 2020

Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide

1 reference

12 December 2020

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

12 December 2020

Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid

1 reference

12 December 2020

Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice

1 reference

12 December 2020

L-serine-mediated release of apolipoprotein E and lipids from microglial cells.

1 reference

12 December 2020

Immunohistochemical study of distribution of apolipoproteins E and D in human cerebral beta amyloid deposits.

1 reference

12 December 2020

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

1 reference

12 December 2020

NMDA receptor antagonists. A new therapeutic approach for Alzheimer's disease.

1 reference

12 December 2020

Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E receptor 2 is involved in neuritic plaque formation in APP sw mice.

1 reference

12 December 2020

Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease

1 reference

12 December 2020

Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

1 reference

12 December 2020

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

12 December 2020

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

1 reference

12 December 2020

Production of basic fibroblast growth factor in cultured rat brain microglia

1 reference

12 December 2020

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

1 reference

12 December 2020

Beta-amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

1 reference

12 December 2020

Demonstration of microglial cells in and around senile (neuritic) plaques in the Alzheimer brain. An immunohistochemical study using a novel monoclonal antibody

1 reference

12 December 2020

Induction of cystine transport activity in human fibroblasts by oxygen

1 reference

12 December 2020

Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease.

1 reference

12 December 2020

Induction of cystine transport activity in mouse peritoneal macrophages

1 reference

12 December 2020

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1 reference

12 December 2020

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

12 December 2020

ApoE immunoreactivity and microglial cells in Alzheimer's disease brain.

1 reference

12 December 2020

Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brain.

1 reference

12 December 2020

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

12 December 2020

An improved fluorescence assay for the determination of lymphocyte-mediated cytotoxicity using flow cytometry

1 reference

12 December 2020

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1 reference

12 December 2020

Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons

1 reference

12 December 2020

A simple and efficient procedure for non-isotopic in situ hybridization to sectioned material.

1 reference

12 December 2020

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

12 December 2020

A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis

1 reference

12 December 2020

Association of A beta 40-positive senile plaques with microglial cells in the brains of patients with Alzheimer's disease and in non-demented aged individuals.

1 reference

12 December 2020

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

12 December 2020

Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by A beta-related peptides

1 reference

12 December 2020

A thrombin cleavage fragment of apolipoprotein E exhibits isoform-specific neurotoxicity.

1 reference

12 December 2020

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures

1 reference

12 December 2020

Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro

1 reference

12 December 2020

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

1 reference

12 December 2020

Basic FGF attenuates amyloid beta-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons.

1 reference

12 December 2020

Neurons promote macrophage proliferation by producing transforming growth factor-beta2.

1 reference

12 December 2020

Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor

1 reference

12 December 2020

beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate

1 reference

12 December 2020

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

1 reference

12 December 2020

Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.

1 reference

12 December 2020

Relationship between apolipoprotein E and the amyloid deposits and dystrophic neurites of Alzheimer's disease.

1 reference

12 December 2020

Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo.

1 reference

12 December 2020

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

1 reference

12 December 2020

Membrane transport of neuronal nitric oxide synthase substrate L-arginine is constitutively expressed with CAT1 and 4F2hc, but not CAT2 or rBAT.

1 reference

12 December 2020

Neuron loss in APP transgenic mice

1 reference

12 December 2020

10.1523/JNEUROSCI.5186-05.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674113&resulttype=core&format=json

11 May 2020

PubMed publication ID

16554485

1 reference