(Q44071719)

English

Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid-beta-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid-beta-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Alzheimer's disease

0 references

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author name string

George Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Harvey B Pollard

2

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Nelson Arispe

3

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

publication date

1 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

number of pages

15

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

1249-1263

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

Relation of age and apolipoprotein E to cognitive function in Down syndrome adults.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

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inferred from DOI database lookup

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Zn2+ interaction with Alzheimer amyloid beta protein calcium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Similarity in calcium channel activity of annexin V and matrix vesicles in planar lipid bilayers

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Vitamin E protects nerve cells from amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-function analysis of the ion channel selectivity filter in human annexin V

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The serpin-enzyme complex receptor recognizes soluble, nontoxic amyloid-beta peptide but not aggregated, cytotoxic amyloid-beta peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical relevance of the quantification of apolipoprotein E in cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoproteins in rat cerebrospinal fluid: A comparison with plasma lipoprotein metabolism and effect of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Possible role of apoptosis in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Annexin V: the key to understanding ion selectivity and voltage regulation?

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

ApoE protects cortical neurones against neurotoxicity induced by the non-fibrillar C-terminal domain of the amyloid-beta peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Theoretical models of the ion channel structure of amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Ionic effects of the Alzheimer's disease beta-amyloid precursor protein and its metabolic fragments

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurodegeneration mediated by glutamate and beta-amyloid peptide: a comparison and possible interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal apoptosis by apolipoprotein E4 through low-density lipoprotein receptor-related protein and heterotrimeric GTPases.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid peptide channels: blockade by zinc and inhibition by Congo red (amyloid channel block).

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of apolipoprotein E during nerve degeneration and regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Properties of cytotoxic peptide-formed ion channels

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Highly sensitive and stable phosphatidylserine liposome aggregation assay for annexins

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of beta amyloid peptides on neurons in hippocampal slice cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

X-ray diffraction analysis of brain lipid membrane structure in Alzheimer's disease and beta-amyloid peptide interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Beta-amyloid peptide interacts specifically with the carboxy-terminal domain of human apolipoprotein E: relevance to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E polymorphism and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium- and phospholipid-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Morphology and toxicity of Abeta-(1-42) dimer derived from neuritic and vascular amyloid deposits of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of annexins as calcium channels in biological membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical application of apolipoprotein E genotyping to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Aggregates of a beta-amyloid peptide are required to induce calcium currents in neuron-like human teratocarcinoma cells: relation to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Nature of mental retardation and dementia in Down syndrome: study with PET, CT, and neuropsychology

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The molecular pathology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: a central role for amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease: genotypes, phenotypes, and treatments

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The levels of cerebrospinal fluid Abeta40 and Abeta42(43) are regulated age-dependently.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular MTT reduction distinguishes the mechanism of action of beta-amyloid from that of tachykinin receptor peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Epistatic effect of APP717 mutation and apolipoprotein E genotype in familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease and possible gene interaction.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer beta-amyloid peptide 25-35: electrostatic interactions with phospholipid membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Displacement currents associated with the insertion of Alzheimer disease amyloid beta-peptide into planar bilayer membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Alzheimer's disease and soluble A beta

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Is Alzheimer's disease an apolipoprotein E amyloidosis?

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Fresh and nonfibrillar amyloid beta protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: evidence for AbetaP-channel-mediated cellular toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900060-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0196-9781(02)00060-8

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 November 2017

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