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Death and dessert: nutrient signalling pathways and ageing
scientific article published on 09 August 2011
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Europe PubMed Central
PMCID
4335171
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25 August 2017
review article
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title
Death and dessert: nutrient signalling pathways and ageing
(English)
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PMCID
4335171
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25 August 2017
author
Nazif Alic
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1
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PMCID
4335171
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25 August 2017
Linda Partridge
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Linda Partridge
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English
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publication date
9 August 2011
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PMCID
4335171
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25 August 2017
published in
Current Opinion in Cell Biology
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PMCID
4335171
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25 August 2017
volume
23
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PMCID
4335171
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25 August 2017
page(s)
738-743
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PMCID
4335171
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25 August 2017
issue
6
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PMCID
4335171
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25 August 2017
cites work
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6 September 2017
Dynamic coordination of innate immune signaling and insulin signaling regulates systemic responses to localized DNA damage
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6 September 2017
Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan
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PubMed Central
reference URL
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6 September 2017
dFOXO-independent effects of reduced insulin-like signaling in Drosophila
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PubMed Central
reference URL
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6 September 2017
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6 September 2017
The plate half-full: status of research on the mechanisms of dietary restriction in Drosophila melanogaster
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Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor
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Lifespan extension by preserving proliferative homeostasis in Drosophila
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6 September 2017
Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network
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A neuromedin U receptor acts with the sensory system to modulate food type-dependent effects on C. elegans lifespan
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Carbon dioxide sensing modulates lifespan and physiology in Drosophila
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6 September 2017
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6 September 2017
DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition
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Reduced IGF-1 signaling delays age-associated proteotoxicity in mice
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6 September 2017
Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
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6 September 2017
4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
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6 September 2017
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
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6 September 2017
Caloric restriction delays disease onset and mortality in rhesus monkeys
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PubMed Central
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6 September 2017
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
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PubMed Central
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6 September 2017
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
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6 September 2017
Regulation of the longevity response to temperature by thermosensory neurons in Caenorhabditis elegans
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6 September 2017
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity
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6 September 2017
Anti-aging activity of the Ink4/Arf locus.
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6 September 2017
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
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6 September 2017
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6 September 2017
Caloric restriction and aging: studies in mice and monkeys
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6 September 2017
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6 September 2017
Unravelling the tumor-suppressive functions of FOXO proteins
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6 September 2017
Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans
1 reference
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PubMed Central
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6 September 2017
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
1 reference
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PubMed Central
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6 September 2017
Cancer and ageing: convergent and divergent mechanisms
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PubMed Central
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6 September 2017
Brain IRS2 signaling coordinates life span and nutrient homeostasis
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6 September 2017
Aging, adiposity, and calorie restriction
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PubMed Central
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6 September 2017
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Opposing activities protect against age-onset proteotoxicity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
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PubMed Central
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6 September 2017
Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
SOD2 functions downstream of Sch9 to extend longevity in yeast
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Extended longevity in mice lacking the insulin receptor in adipose tissue
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Oncogenic kinase signalling
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PubMed Central
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6 September 2017
A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Regulation of longevity and stress resistance by Sch9 in yeast
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
A C. elegans mutant that lives twice as long as wild type
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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6 September 2017
Specific insulin-like peptides encode sensory information to regulate distinct developmental processes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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23 June 2018
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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23 June 2018
FoxO transcription factors suppress Myc-driven lymphomagenesis via direct activation of Arf.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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23 June 2018
Regulation of lifespan by sensory perception in Caenorhabditis elegans
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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23 June 2018
Regulation of Drosophila life span by olfaction and food-derived odors.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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1 September 2018
Long-lived Drosophila with overexpressed dFOXO in adult fat body.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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1 September 2018
Regulation of C. elegans longevity by specific gustatory and olfactory neurons
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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1 September 2018
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335171
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3 December 2018
Food, reproduction and L'ongevity: Is the extended lifespan of calorie-restricted animals an evolutionary adaptation?
1 reference
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PubMed Central
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3 December 2018
Loss of pregnancy-associated plasma protein A extends lifespan in mice
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21835601
retrieved
12 December 2020
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Identifiers
DOI
10.1016/J.CEB.2011.07.006
1 reference
stated in
Europe PubMed Central
PMCID
4335171
retrieved
25 August 2017
PMCID
4335171
1 reference
stated in
Europe PubMed Central
PMCID
4335171
retrieved
25 August 2017
PubMed ID
21835601
1 reference
stated in
Europe PubMed Central
PMCID
4335171
retrieved
25 August 2017
ResearchGate publication ID
51565682
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